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Kang, H. Homogeneous Catalysis. Encyclopedia. Available online: https://encyclopedia.pub/entry/60345 (accessed on 03 October 2026).
Kang H. Homogeneous Catalysis. Encyclopedia. Available at: https://encyclopedia.pub/entry/60345. Accessed October 03, 2026.
Kang, Helena. "Homogeneous Catalysis" Encyclopedia, https://encyclopedia.pub/entry/60345 (accessed October 03, 2026).
Kang, H. (2026, September 23). Homogeneous Catalysis. In Encyclopedia. https://encyclopedia.pub/entry/60345
Kang, Helena. "Homogeneous Catalysis." Encyclopedia. Web. 23 September, 2026.
Homogeneous Catalysis
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Homogeneous catalysis occurs when the catalyst and reactants are present in the same macroscopic phase, most commonly as molecularly dispersed species in a liquid solution. The catalyst may be a neutral molecule, coordination complex, ion, or ion pair, but it undergoes a sequence of elementary steps that regenerates the catalytically active species. For metal complexes, these steps can include ligand association or dissociation, oxidative addition, migratory insertion, and reductive elimination; homogeneous organocatalysis instead proceeds through covalent or noncovalent activation by an organic catalyst. The defining criterion is phase and molecular dispersion, not catalyst composition: both metal and metal-free catalysts can be homogeneous. Molecular catalysts that transform carboxylic acids illustrate the breadth of substrates addressed by homogeneous cycles [1]. The concept is distinguished from heterogeneous catalysis, where the catalyst forms a separate phase and reaction occurs at an interface, although immobilized or biphasic systems can combine features of both classes [2].

homogeneous catalysis molecular catalysts solution-phase catalysis catalyst recovery

References

  1. Lukas J. Gooßen; Nuria Rodríguez; Käthe Gooßen; Carboxylic Acids as Substrates in Homogeneous Catalysis. Angew. Chem. Int. Ed. 2008, 47, 3100-3120. [CrossRef]
  2. David J. Cole-Hamilton; Homogeneous Catalysis--New Approaches to Catalyst Separation, Recovery, and Recycling. Science 2003, 299, 1702-1706. [CrossRef]
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Subjects: Chemistry, Organic
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Update Date: 23 Sep 2026
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