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Office, E.E. Cervicovaginal Microbiome. Encyclopedia. Available online: https://encyclopedia.pub/entry/59059 (accessed on 21 October 2026).
Office EE. Cervicovaginal Microbiome. Encyclopedia. Available at: https://encyclopedia.pub/entry/59059. Accessed October 21, 2026.
Office, Encyclopedia Editorial. "Cervicovaginal Microbiome" Encyclopedia, https://encyclopedia.pub/entry/59059 (accessed October 21, 2026).
Office, E.E. (2025, September 25). Cervicovaginal Microbiome. In Encyclopedia. https://encyclopedia.pub/entry/59059
Office, Encyclopedia Editorial. "Cervicovaginal Microbiome." Encyclopedia. Web. 25 September, 2025.

Cervicovaginal Microbiome

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The cervicovaginal microbiome (CVM) denotes the microbial community that inhabits the lower female reproductive tract, principally the vaginal lumen and ectocervix, and the array of host–microbe interactions that occur there. The CVM includes bacteria, viruses, fungi, and eukaryotic microbes, plus metabolites and host immune factors present in cervicovaginal fluid. The composition and activity of this ecosystem influence local physiology, susceptibility to infections, reproductive outcomes, and long-term gynecologic health.

cervicovaginal microbiome vaginal microbiota 16S rRNA gene

References

  1. Ravel J, Gajer P, Abdo Z, et al. Vaginal microbiome of reproductive-age women. Proc Natl Acad Sci U S A. 2011;108 Suppl 1:4680–4687. https://doi.org/10.1073/pnas.1002611107.
  2. Gajer P, Brotman RM, Bai G, et al. Temporal dynamics of the human vaginal microbiota. Sci Transl Med. 2012;4(132):132ra52. https://doi.org/10.1126/scitranslmed.3003605.
  3. Mirmonsef P, Gilbert D, Zariffard MR, et al. The effects of commensal bacteria on innate immune responses in the female genital tract. Am J Reprod Immunol. 2011;65(3):190–195. https://doi.org/10.1111/j.1600-0897.2010.00942.x.
  4. Boris S, Barbés C. Role played by lactobacilli in controlling the population of vaginal pathogens. Microbes Infect. 2000;2(5):543–546. https://doi.org/10.1016/S1286-4579(00)00313-0.
  5. Ravel J, Brotman RM, Gajer P, et al. Daily temporal dynamics of vaginal microbiota before, during and after episodes of bacterial vaginosis. Microbiome. 2013;1:29. https://doi.org/10.1186/2049-2618-1-29.
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Subjects: Obstetrics & Gynaecology
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