Ollier Disease

Version	Summary	Created by	Modification	Content Size	Created at	Operation
1		Rita Xu	+ 507 word(s)	507	2020-12-15 07:33:46

Cite

If you have any further questions, please contact Encyclopedia Editorial Office.

Select a Style

Xu, R. Ollier Disease. Encyclopedia. Available online: https://encyclopedia.pub/entry/4741 (accessed on 27 September 2026).

Xu R. Ollier Disease. Encyclopedia. Available at: https://encyclopedia.pub/entry/4741. Accessed September 27, 2026.

Xu, Rita. "Ollier Disease" Encyclopedia, https://encyclopedia.pub/entry/4741 (accessed September 27, 2026).

Xu, R. (2020, December 24). Ollier Disease. In Encyclopedia. https://encyclopedia.pub/entry/4741

Xu, Rita. "Ollier Disease." Encyclopedia. Web. 24 December, 2020.

Ollier Disease

Edit

This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/ollier-disease

Ollier disease is a disorder characterized by multiple enchondromas, which are noncancerous (benign) growths of cartilage that develop within the bones. These growths most commonly occur in the limb bones, especially in the bones of the hands and feet; however, they may also occur in the skull, ribs, and bones of the spine (vertebrae). Enchondromas may result in severe bone deformities, shortening of the limbs, and fractures.

genetic conditions

References

Amary MF, Damato S, Halai D, Eskandarpour M, Berisha F, Bonar F, McCarthy S,Fantin VR, Straley KS, Lobo S, Aston W, Green CL, Gale RE, Tirabosco R, FutrealA, Campbell P, Presneau N, Flanagan AM. Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2. Nat Genet. 2011 Nov6;43(12):1262-5. doi: 10.1038/ng.994.
Herget GW, Strohm P, Rottenburger C, Kontny U, Krauß T, Bohm J, Sudkamp N, UhlM. Insights into Enchondroma, Enchondromatosis and the risk of secondaryChondrosarcoma. Review of the literature with an emphasis on the clinicalbehaviour, radiology, malignant transformation and the follow up. Neoplasma.2014;61(4):365-78. doi: 10.4149/neo_2014_046. Review.
Pansuriya TC, Kroon HM, Bovée JV. Enchondromatosis: insights on the different subtypes. Int J Clin Exp Pathol. 2010 Jun 26;3(6):557-69. Review.
Pansuriya TC, van Eijk R, d'Adamo P, van Ruler MA, Kuijjer ML, Oosting J,Cleton-Jansen AM, van Oosterwijk JG, Verbeke SL, Meijer D, van Wezel T, Nord KH, Sangiorgi L, Toker B, Liegl-Atzwanger B, San-Julian M, Sciot R, Limaye N,Kindblom LG, Daugaard S, Godfraind C, Boon LM, Vikkula M, Kurek KC, Szuhai K,French PJ, Bovée JV. Somatic mosaic IDH1 and IDH2 mutations are associated withenchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome. Nat Genet. 2011 Nov 6;43(12):1256-61. doi: 10.1038/ng.1004.
Silve C, Jüppner H. Ollier disease. Orphanet J Rare Dis. 2006 Sep 22;1:37.Review.
Superti-Furga A, Spranger J, Nishimura G. Enchondromatosis revisited: newclassification with molecular basis. Am J Med Genet C Semin Med Genet. 2012 Aug15;160C(3):154-64. doi: 10.1002/ajmg.c.31331.
Verdegaal SH, Bovée JV, Pansuriya TC, Grimer RJ, Ozger H, Jutte PC, San JulianM, Biau DJ, van der Geest IC, Leithner A, Streitbürger A, Klenke FM, Gouin FG,Campanacci DA, Marec-Berard P, Hogendoorn PC, Brand R, Taminiau AH. Incidence,predictive factors, and prognosis of chondrosarcoma in patients with Ollierdisease and Maffucci syndrome: an international multicenter study of 161patients. Oncologist. 2011;16(12):1771-9. doi: 10.1634/theoncologist.2011-0200.

©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.

Upload a video for this entry

Information

Subjects: Genetics & Heredity

Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Rita Xu

View Times: 877

Entry Collection: MedlinePlus

Update Date: 24 Dec 2020

Table of Contents

Video Upload Options

References