Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 handwiki Dean Liu -- 1557 2022-11-22 01:34:48

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
HandWiki. Primary Polydipsia. Encyclopedia. Available online: https://encyclopedia.pub/entry/35793 (accessed on 25 September 2026).
HandWiki. Primary Polydipsia. Encyclopedia. Available at: https://encyclopedia.pub/entry/35793. Accessed September 25, 2026.
HandWiki. "Primary Polydipsia" Encyclopedia, https://encyclopedia.pub/entry/35793 (accessed September 25, 2026).
HandWiki. (2022, November 22). Primary Polydipsia. In Encyclopedia. https://encyclopedia.pub/entry/35793
HandWiki. "Primary Polydipsia." Encyclopedia. Web. 22 November, 2022.
Primary Polydipsia
Edit

Primary polydipsia, or psychogenic polydipsia, is a form of polydipsia characterised by excessive fluid intake in the absence of physiological stimuli to drink. Psychogenic polydipsia which is caused by psychiatric disorders, often schizophrenia, is often accompanied by the sensation of dry mouth. Some forms of polydipsia are explicitly non-psychogenic. Primary polydipsia is a diagnosis of exclusion.

polydipsia excessive fluid intake schizophrenia

References

  1. Gill, Melissa; McCauley, MacDara (2015-01-21). "Psychogenic Polydipsia: The Result, or Cause of, Deteriorating Psychotic Symptoms? A Case Report of the Consequences of Water Intoxication" (in en). Case Reports in Psychiatry 2015: 846459. doi:10.1155/2015/846459. ISSN 2090-682X. PMID 25688318.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4320790
  2. de Leon, Jose; Verghese, Cherian; Tracy, Joseph I.; Josiassen, Richard C.; Simpson, George M. (1994). "Polydipsia and water intoxication in psychiatric patients: A review of the epidemiological literature". Biological Psychiatry 35 (6): 408–419. doi:10.1016/0006-3223(94)90008-6. PMID 8018788.  https://dx.doi.org/10.1016%2F0006-3223%2894%2990008-6
  3. Hutcheon, Donald. "Psychogenic Polydipsia (Excessive Fluid seeking Behaviour)". http://www.apadivisions.org/division-31/publications/articles/british-columbia/psychogenic-polydipsia.pdf. 
  4. Hedges, D.; Jeppson, K.; Whitehead, P. (2003). "Antipsychotic medication and seizures: A review". Drugs of Today 39 (7): 551–557. doi:10.1358/dot.2003.39.7.799445. PMID 12973403.  https://dx.doi.org/10.1358%2Fdot.2003.39.7.799445
  5. Perch, Julia; O’Connor, Kevin M.. "Insatiable thirst: Managing polydipsia". Current Psychiatry 8 (7): 82. http://www.mdedge.com/currentpsychiatry/article/63646/insatiable-thirst-managing-polydipsia#bib2. 
  6. Ferrier, I N (1985-12-07). "Water intoxication in patients with psychiatric illness.". British Medical Journal (Clinical Research Ed.) 291 (6509): 1594–1596. doi:10.1136/bmj.291.6509.1594. ISSN 0267-0623. PMID 3935199.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1418423
  7. Moses, A. M.; Clayton, B.; Hochhauser, L. (1992-09-01). "Use of T1-weighted MR imaging to differentiate between primary polydipsia and central diabetes insipidus." (in en). American Journal of Neuroradiology 13 (5): 1273–1277. ISSN 0195-6108. PMID 1414815. http://www.ajnr.org/content/13/5/1273. 
  8. Nagashima, Tomohisa; Inoue, Makoto; Kitamura, Soichiro; Kiuchi, Kuniaki; Kosaka, Jun; Okada, Koji; Kishimoto, Naoko; Taoka, Toshiaki et al. (2012-01-01). "Brain structural changes and neuropsychological impairments in male polydipsic schizophrenia". BMC Psychiatry 12: 210. doi:10.1186/1471-244X-12-210. ISSN 1471-244X. PMID 23181904.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3532364
  9. "Polydipsia linked to brain alterations in schizophrenia". News-Medical.net. 2012-11-28. http://www.news-medical.net/news/20121128/Polydipsia-linked-to-brain-alterations-in-schizophrenia.aspx. 
  10. "Psychogenic polydipsia – Diagnosis – Approach". British Medical Journal. 5 May 2016. http://bestpractice.bmj.com/best-practice/monograph/865/diagnosis/step-by-step.html. Retrieved 29 October 2016. 
  11. "Primary polydipsia – General Practice Notebook". http://www.gpnotebook.co.uk/simplepage.cfm?ID=-2087059408. 
  12. Zerbe, R. L.; Robertson, G. L. (1981-12-24). "A comparison of plasma vasopressin measurements with a standard indirect test in the differential diagnosis of polyuria". The New England Journal of Medicine 305 (26): 1539–1546. doi:10.1056/NEJM198112243052601. ISSN 0028-4793. PMID 7311993.  https://dx.doi.org/10.1056%2FNEJM198112243052601
  13. Rippe, James M.; Irwin, Richard S. (2008). Irwin and Rippe's Intensive care medicine. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins. p. 909. ISBN 978-0-7817-9153-3. 
  14. "Psychotropic-induced dry mouth: Don't overlook this potentially serious side effect". Current Psychiatry 10 (12): 54–58. December 2011. http://www.mdedge.com/currentpsychiatry/article/64550/depression/psychotropic-induced-dry-mouth-dont-overlook-potentially. 
  15. Swift, R.; Davidson, D. (1998-01-01). "Alcohol hangover: mechanisms and mediators". Alcohol Health and Research World 22 (1): 54–60. ISSN 0090-838X. PMID 15706734.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=6761819
  16. Taivainen, H.; Laitinen, K.; Tähtelä, R.; Kilanmaa, K.; Välimäki, M. J. (1995-06-01). "Role of plasma vasopressin in changes of water balance accompanying acute alcohol intoxication". Alcoholism, Clinical and Experimental Research 19 (3): 759–762. doi:10.1111/j.1530-0277.1995.tb01579.x. ISSN 0145-6008. PMID 7573805.  https://dx.doi.org/10.1111%2Fj.1530-0277.1995.tb01579.x
  17. Fichman, M. P.; Kleeman, C. R.; Bethune, J. E. (1970-01-01). "Inhibition of Antidiuretic Hormone Secretion by Diphenylhydantoin" (in en). Archives of Neurology 22 (1): 45–53. doi:10.1001/archneur.1970.00480190049008. ISSN 0003-9942. PMID 5409600.  https://dx.doi.org/10.1001%2Farchneur.1970.00480190049008
  18. "Psychogenic polydipsia – Diagnosis – Differential diagnosis". British Medical Journal. 5 May 2016. http://bestpractice.bmj.com/best-practice/monograph/865/diagnosis/differential.html. Retrieved 29 October 2016. 
  19. Blum, Alexander (1984-11-23). "The Possible Role of Tobacco Cigarette Smoking in Hyponatremia of Long-term Psychiatric Patients". JAMA: The Journal of the American Medical Association 252 (20): 2864. doi:10.1001/jama.1984.03350200050022. ISSN 0098-7484.  https://dx.doi.org/10.1001%2Fjama.1984.03350200050022
  20. Jose, C. J.; Evenson, R. C. (1980-08-01). "Antecedents of self-induced water intoxication. A preliminary report". The Journal of Nervous and Mental Disease 168 (8): 498–500. doi:10.1097/00005053-198008000-00009. ISSN 0022-3018. PMID 7400803.  https://dx.doi.org/10.1097%2F00005053-198008000-00009
  21. de Leon, Jose (2003-02-01). "Polydipsia—a study in a long-term psychiatric unit". European Archives of Psychiatry and Clinical Neuroscience 253 (1): 37–39. doi:10.1007/s00406-003-0403-z. ISSN 0940-1334. PMID 12664312.  https://dx.doi.org/10.1007%2Fs00406-003-0403-z
  22. "Psychogenic polydipsia – Theory – Aetiology". British Medical Journal. 5 May 2016. http://bestpractice.bmj.com/best-practice/monograph/865/basics/aetiology.html. Retrieved 29 October 2016. 
  23. Mayo Clinic internal medicine board review.. Ghosh, Amit., Mayo Foundation for Medical Education and Research., Mayo Clinic. (9th ed.). [Rochester, MN.]: Mayo Clinic Scientific Press. 2010. pp. 192. ISBN 9780199755691. OCLC 646395464.  http://www.worldcat.org/oclc/646395464
  24. Assessment (Lippincott Manual Handbook). Springhouse Publishing Co. 2006. pp. 189. ISBN 978-1582559391. 
  25. Leadbetter, Shutty Jr., Higgins, Pavalonis, Robert, Michael, Patricia, Diane (1994). "Multidisciplinary Approach to Psychosis, Intermittent Hyponatremia, and Polydipsia". Schizophrenia Bulletin 20 (2): 375–385. doi:10.1093/schbul/20.2.375. PMID 8085139.  https://dx.doi.org/10.1093%2Fschbul%2F20.2.375
  26. Dundas, Brian; Harris, Melissa; Narasimhan, Meera (2007-07-03). "Psychogenic polydipsia review: Etiology, differential, and treatment" (in en). Current Psychiatry Reports 9 (3): 236–241. doi:10.1007/s11920-007-0025-7. ISSN 1523-3812. PMID 17521521.  https://dx.doi.org/10.1007%2Fs11920-007-0025-7
  27. "Psychogenic polydipsia – Management – Step by step". British Medical Journal. 5 May 2016. http://bestpractice.bmj.com/best-practice/monograph/865/treatment/details.html. Retrieved 29 October 2016. 
  28. Bowen, L.; Glynn, S. M.; Marshall, B. D.; Kurth, C. L.; Hayden, J. L. (1990-03-01). "Successful behavioral treatment of polydipsia in a schizophrenic patient". Journal of Behavior Therapy and Experimental Psychiatry 21 (1): 53–61. doi:10.1016/0005-7916(90)90049-q. ISSN 0005-7916. PMID 2373769. (Subscription content?) https://dx.doi.org/10.1016%2F0005-7916%2890%2990049-q
  29. Costanzo, Erin S.; Antes, Lisa M.; Christensen, Alan J. (2016-11-01). "Behavioral and medical treatment of chronic polydipsia in a patient with schizophrenia and diabetes insipidus". Psychosomatic Medicine 66 (2): 283–286. doi:10.1097/01.psy.0000116717.42624.68. ISSN 1534-7796. PMID 15039516. (Subscription content?) https://dx.doi.org/10.1097%2F01.psy.0000116717.42624.68
  30. Lee, H. S.; Kwon, K. Y.; Alphs, L. D.; Meltzer, H. Y. (1991-06-01). "Effect of clozapine on psychogenic polydipsia in chronic schizophrenia". Journal of Clinical Psychopharmacology 11 (3): 222–223. doi:10.1097/00004714-199106000-00022. ISSN 0271-0749. PMID 2066464.  https://dx.doi.org/10.1097%2F00004714-199106000-00022
  31. Kruse, D.; Pantelis, C.; Rudd, R.; Quek, J.; Herbert, P.; McKinley, M. (2001-02-01). "Treatment of psychogenic polydipsia: comparison of risperidone and olanzapine, and the effects of an adjunctive angiotensin-II receptor blocking drug (irbesartan)". The Australian and New Zealand Journal of Psychiatry 35 (1): 65–68. doi:10.1046/j.1440-1614.2001.00847.x. ISSN 0004-8674. PMID 11270459. (Subscription content?) https://dx.doi.org/10.1046%2Fj.1440-1614.2001.00847.x
  32. Goh, Kian Peng (2004-05-15). "Management of Hyponatremia – American Family Physician". American Family Physician 69 (10): 2387–2394. http://www.aafp.org/afp/2004/0515/p2387.html. Retrieved 2016-10-29. 
  33. "Psychogenic polydipsia – Management – Emerging treatments". British Medical Journal. 5 May 2016. http://bestpractice.bmj.com/best-practice/monograph/865/treatment/emerging.html. Retrieved 29 October 2016. 
  34. Greendyke, Robert M.; Bernhardt, Alan J.; Tasbas, Hedy E.; Lewandowski, Kathleen S. (1998-04-01). "Polydipsia in Chronic Psychiatric Patients: Therapeutic Trials of Clonidine and Enalapril" (in en). Neuropsychopharmacology 18 (4): 272–281. doi:10.1016/S0893-133X(97)00159-0. ISSN 0893-133X. PMID 9509495.  https://dx.doi.org/10.1016%2FS0893-133X%2897%2900159-0
  35. Shevitz, S. A.; Jameison, R. C.; Petrie, W. M.; Crook, J. E. (1980-04-01). "Compulsive water drinking treated with high dose propranolol". The Journal of Nervous and Mental Disease 168 (4): 246–248. doi:10.1097/00005053-198004000-00011. ISSN 0022-3018. PMID 7365485.  https://dx.doi.org/10.1097%2F00005053-198004000-00011
  36. Douglas, Ivor (2006-09-01). "Hyponatremia: why it matters, how it presents, how we can manage it". Cleveland Clinic Journal of Medicine 73 Suppl 3: S4–12. doi:10.3949/ccjm.73.suppl_3.s4. ISSN 0891-1150. PMID 16970147. https://semanticscholar.org/paper/cd1f8147bc7b4d54ed6efad03eb10fe65304a919. 
  37. Takagi, Shunsuke; Watanabe, Yutaka; Imaoka, Takefumi; Sakata, Masuhiro; Watanabe, Masako (2017-02-01). "Treatment of psychogenic polydipsia with acetazolamide: a report of 5 cases". Clinical Neuropharmacology 34 (1): 5–7. doi:10.1097/WNF.0b013e318205070b. ISSN 1537-162X. PMID 21242740. (Subscription content?) https://dx.doi.org/10.1097%2FWNF.0b013e318205070b
  38. Meulendijks, Didier; Mannesse, Cyndie K.; Jansen, Paul A. F.; van Marum, Rob J.; Egberts, Toine C. G. (2010-02-01). "Antipsychotic-induced hyponatraemia: a systematic review of the published evidence". Drug Safety 33 (2): 101–114. doi:10.2165/11319070-000000000-00000. ISSN 1179-1942. PMID 20082537. (Subscription content?) https://dx.doi.org/10.2165%2F11319070-000000000-00000
  39. "Non-psychogenic primary polydipsia in autoimmune chronic active hepatitis with severe hyperglobulinaemia". Gut 29 (4): 548–9. April 1988. doi:10.1136/gut.29.4.548. PMID 3371724.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1433532
  40. Falk, John L. (1969-05-01). "Conditions Producing Psychogenic Polydipsia in Animals*" (in en). Annals of the New York Academy of Sciences 157 (2): 569–593. doi:10.1111/j.1749-6632.1969.tb12908.x. ISSN 1749-6632. PMID 5255630. Bibcode: 1969NYASA.157..569F.  https://dx.doi.org/10.1111%2Fj.1749-6632.1969.tb12908.x
More
Upload a video for this entry
Information
Subjects: Others
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register :
View Times: 1.8K
Entry Collection: HandWiki
Revision: 1 time (View History)
Update Date: 22 Nov 2022
Notice
You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
OK
Confirm
Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
Yes
No
${ textCharacter }/${ maxCharacter }
Submit
Cancel
There is no comment~
${ textCharacter }/${ maxCharacter }
Submit
Cancel
${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
Submit
Cancel
Confirm
Are you sure to Delete?
Yes No
Academic Video Service