Hot Most Recent
|Ver.||Summary||Created by||Modification||Content Size||Created at||Operation|
|1||+ 186 word(s)||186||2020-09-09 08:03:28||||
|2||-37 word(s)||149||2020-09-23 04:21:54||||
Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group of hereditary connective tissue disorders involving joint hyperlaxity, cutaneous hyperelasticity, and tissue fragility.
A revised classification containing 13 subtypes was published by the International EDS Consortium, with a number of clinical conditions to guide and improve the diagnosis of each subtype. In the European Union, a disease is considered ‘rare’ if it affects fewer than one in two thousand people. In the case of EDS, the prevalence varies, depending on the type: between 1:30,000 (classical type) and < 1:1,000,000 (arthrochalasia type), whereas for the rarest form (the periodontitis type), the prevalence is unknown.
EDS’ oral conditions have been described as periodontitis, temporomandibular dysfunctions, bleeding tendencies, enamel hypoplasia, shape abnormalities of the teeth and changes in the number of teeth, a high palate, dysgnathia, and malocclusion, as well as decreased effects of local anesthesia.