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Human Skin Microbiome
The skin is the common coat of the body and is the largest organ of the human organism. Its role is to provide an optimal environment for deeper tissues, by separating them from the external environment, and at the same time ensuring contact with it by exchanging substances and receiving stimuli.
Figure 1. The intrinsic and extrinsic factors that influence the skin microbiome.
2. Microorganisms Inhabiting the Skin
3. Interactions between Skin Microorganisms
The dominant resident species of skin bacteria are commensals. Together with immune cells and keratinized skin cells (replaced every four weeks), these are responsible for the appropriate skin immune barrier functioning . There are diverse mechanisms of skin immune system support that are associated with the activity of the microorganisms. While a properly functioning microbiome of healthy skin supports the body’s immune barrier, its transition into a dysbiosis state may lead to numerous systemic disorders. Dysbiosis, which is a disturbance of the structural and functional balance of the normal microbiome, is caused by internal and external stressors. Factors used in the fight against dysbiosis and helping to restore the balance of the skin microbiota include the use of probiotics and prebiotics. Dysbiosis alters the proportions of organisms in the healthy skin microbiome and may trigger the pathogenic potential of the commensals. Examples of diseases associated with the skin microbiome composition disturbance include acne, atopic dermatitis (AD), and dandruff .
4. Skin Disinfection and Its Influence on the Microbiome Condition
The entry is from 10.3390/microorganisms9030543
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