You're using an outdated browser. Please upgrade to a modern browser for the best experience.
Polar Chromosomes
  • View Times: 50
  • |
  • Release Date: 2022-05-26
  • mitosis
  • mitotic spindle
  • prometaphase
  • aneuploidy
  • chromosome congression
  • chromosome mis-segregation
Video Introduction

This video is adapted from 10.3390/cells11091531

The process of chromosome congression and alignment is at the core of mitotic fidelity. In this video, researchers discuss distinct spatial routes that the chromosomes take to align during prometaphase, which are characterized by distinct biomolecular requirements. Peripheral polar chromosomes are an intriguing case as their alignment depends on the activity of kinetochore motors, polar ejection forces, and a transition from lateral to end-on attachments to microtubules, all of which can result in the delayed alignment of these chromosomes.

Full Transcript
Video Production Service