Aerosol-Mediated Non-Viral Lung Gene Therapy
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  • Release Date: 2022-03-25
  • aminoglycoside-based cationic lipids
  • cystic fibrosis
  • lipidic formulations
  • lung gene therapy
  • nebulization
  • structure-activity
  • in vivo
Video Introduction

This video is adapted from 10.3390/pharmaceutics14010025

The video shows the experimental procedure used to dose animals via aerosol, which allowed to highlight the potential of aminoglycoside-based cationic liposomes for non-viral lung gene therapy.

All procedures were carried out with personal licenses under protocols (APAFIS #22194-2019092711061392) approved by the Laboratory Animal Care Guidelines and the Institutional Animal Care and Research Advisory Committee at both the University of Oxford (United Kingdom) and the University of Brest (France).

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