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HandWiki is the world's largest wiki-style encyclopedia dedicated to science, technology and computing. It allows you to create and edit articles as long as you have external citations and login account. In addition, this is a content management environment that can be used for collaborative editing of original scholarly content, such as books, manuals, monographs and tutorials.

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Ghauri (Missile)
The Ghauri–I (Urdu: غوری-ا‎; official codename: Hatf–5 Ghauri–I) is a land-based surface-to-surface medium-range ballistic missile, in current service with the Pakistan Army's Strategic Forces Command— a subordinate command of Strategic Plans Division. Influenced from the design of Nodong-1 of North Korea, its extensive modification and engineering took place in Kahuta Research Laboratories (KRL) in 1990s with an objective of developing an electronic system that uses a single stage liquid fuel rocket motor to carry a payload of 700 kg to a range of 1,500 km. This is enough to reach most, if not all of India. Two variants of the Ghauri were produced under the secretive missile research programme started in 1987 and the development of a third variant was cancelled. The Ghauri-II uses increased motor assembly length and improved propellants for an increased range of 2,300 km (1,400 mi). The missile is named after Shahabuddin Muhammad Ghauri, while the "Hatf" designation originates from the name of the sword or lance of the Islamic prophet Muhammad.
  • 8.0K
  • 09 Nov 2022
Topic Review
Uniaxial Tensile Test
Tensile testing, also known as tension testing, is a fundamental materials science and engineering test in which a sample is subjected to a controlled tension until failure. Properties that are directly measured via a tensile test are ultimate tensile strength, breaking strength, maximum elongation and reduction in area. From these measurements the following properties can also be determined: Young's modulus, Poisson's ratio, yield strength, and strain-hardening characteristics. Uniaxial tensile testing is the most commonly used for obtaining the mechanical characteristics of isotropic materials. Some materials use biaxial tensile testing. The main difference between these testing machines being how load is applied on the materials.
  • 10.4K
  • 07 Nov 2022
Topic Review
Lustre (File System)
Lustre is a type of parallel distributed file system, generally used for large-scale cluster computing. The name Lustre is a portmanteau word derived from Linux and cluster. Lustre file system software is available under the GNU General Public License (version 2 only) and provides high performance file systems for computer clusters ranging in size from small workgroup clusters to large-scale, multi-site systems. Since June 2005, Lustre has consistently been used by at least half of the top ten, and more than 60 of the top 100 fastest supercomputers in the world, including the world's No. 1 ranked TOP500 supercomputer in June 2020, Fugaku, as well as previous top supercomputers such as Titan and Sequoia. Lustre file systems are scalable and can be part of multiple computer clusters with tens of thousands of client nodes, tens of petabytes (PB) of storage on hundreds of servers, and more than a terabyte per second (TB/s) of aggregate I/O throughput. This makes Lustre file systems a popular choice for businesses with large data centers, including those in industries such as meteorology, simulation, oil and gas, life science, rich media, and finance. The I/O performance of Lustre has widespread impact on these applications and has attracted broad attention.
  • 2.4K
  • 07 Nov 2022
Topic Review
Water Intoxication
Water intoxication, also known as water poisoning, hyperhydration, overhydration, or water toxemia, is a potentially fatal disturbance in brain functions that results when the normal balance of electrolytes in the body is pushed outside safe limits by excessive water intake. Under normal circumstances, accidentally consuming too much water is exceptionally rare. Nearly all deaths related to water intoxication in normal individuals have resulted either from water-drinking contests, in which individuals attempt to consume large amounts of water, or from long bouts of exercise during which excessive amounts of fluid were consumed. In addition, water cure, a method of torture in which the victim is forced to consume excessive amounts of water, can cause water intoxication. Water, just like any other substance, can be considered a poison when over-consumed in a brief period of time. Water intoxication mostly occurs when water is being consumed in a high quantity without adequate electrolyte intake. Excess of body water may also be a result of a medical condition or improper treatment; see "hyponatremia" for some examples. Water is considered one of the least toxic chemical compounds, with an LD50 of over 150 ml/kg in rats.
  • 1.7K
  • 07 Nov 2022
Topic Review
Pathogenic Bacteria
Pathogenic bacteria are bacteria that can cause disease. This article focuses on the bacteria that are pathogenic to humans. Most species of bacteria are harmless and are often beneficial but others can cause infectious diseases. The number of these pathogenic species in humans is estimated to be fewer than a hundred. By contrast, several thousand species are part of the gut flora present in the digestive tract. The body is continually exposed to many species of bacteria, including beneficial commensals, which grow on the skin and mucous membranes, and saprophytes, which grow mainly in the soil and in decaying matter. The blood and tissue fluids contain nutrients sufficient to sustain the growth of many bacteria. The body has defence mechanisms that enable it to resist microbial invasion of its tissues and give it a natural immunity or innate resistance against many microorganisms. Pathogenic bacteria are specially adapted and endowed with mechanisms for overcoming the normal body defences, and can invade parts of the body, such as the blood, where bacteria are not normally found. Some pathogens invade only the surface epithelium, skin or mucous membrane, but many travel more deeply, spreading through the tissues and disseminating by the lymphatic and blood streams. In some rare cases a pathogenic microbe can infect an entirely healthy person, but infection usually occurs only if the body's defence mechanisms are damaged by some local trauma or an underlying debilitating disease, such as wounding, intoxication, chilling, fatigue, and malnutrition. In many cases, it is important to differentiate infection and colonization, which is when the bacteria are causing little or no harm. Caused by Mycobacterium tuberculosis bacteria, one of the diseases with the highest disease burden is tuberculosis, which killed 1.4 million people in 2019, mostly in sub-Saharan Africa. Pathogenic bacteria contribute to other globally important diseases, such as pneumonia, which can be caused by bacteria such as Streptococcus, Pneumococcus and Pseudomonas, and foodborne illnesses, which can be caused by bacteria such as Shigella, Campylobacter, and Salmonella. Pathogenic bacteria also cause infections such as tetanus, typhoid fever, diphtheria, syphilis, and leprosy. Pathogenic bacteria are also the cause of high infant mortality rates in developing countries. Most pathogenic bacteria can be grown in cultures and identified by Gram stain and other methods. Bacteria grown in this way are often tested to find which antibiotics will be an effective treatment for the infection. For hitherto unknown pathogens, Koch's postulates are the standard to establish a causative relationship between a microbe and a disease.
  • 7.5K
  • 07 Nov 2022
Topic Review
Compression of Genomic Sequencing Data
High-throughput sequencing technologies have led to a dramatic decline of genome sequencing costs and to an astonishingly rapid accumulation of genomic data. These technologies are enabling ambitious genome sequencing endeavours, such as the 1000 Genomes Project and 1001 (Arabidopsis thaliana) Genomes Project. The storage and transfer of the tremendous amount of genomic data have become a mainstream problem, motivating the development of high-performance compression tools designed specifically for genomic data. A recent surge of interest in the development of novel algorithms and tools for storing and managing genomic re-sequencing data emphasizes the growing demand for efficient methods for genomic data compression.
  • 1.2K
  • 07 Nov 2022
Topic Review
Arba'een
Template:HusaynTemplate:Islamic Culture Arba'ein (Arabic: الأربعين), Chehellom (Persian: چهلم‎, "the fortieth day") is a Shia religious observance that occurs forty days after the Day of Ashura. It commemorates the martyrdom of Al-Husayn ibn Ali, the grandson of Muhammad, who was martyred on the 10th day of the month of Muharram.Imam Hussain ibn Ali and 71 of his companions were martyred by Ubayd Allah ibn Ziyad's army under the governance of Yazeed Malhoon in the Battle of Karbala in 61 AH (680 CE). Arba'ein or forty days is also the usual length of mourning after the death of a family member or loved one in many Muslim traditions. Arba'ein is the largest annual pilgrimage in the world, in which up to 40 million (In reality, there are no reliable methods for tallying the number of site visitors. This is an entirely estimated set of statistics. Logically, it is possible to gather 40m persons on a small city) people go to the city of Karbala in Iraq.
  • 3.7K
  • 07 Nov 2022
Topic Review
History of Emerging Infectious Diseases
The discovery of disease-causing pathogens is an important activity in the field of medical science. Many viruses, bacteria, protozoa, fungi, helminthes and prions are identified as a confirmed or potential pathogen. In the United States, a Centers for Disease Control program, begun in 1995, identified over a hundred patients with life-threatening illnesses that were considered to be of an infectious cause, but that could not be linked to a known pathogen. The association of pathogens with disease can be a complex and controversial process, in some cases requiring decades or even centuries to achieve.
  • 1.4K
  • 07 Nov 2022
Topic Review
SpiderMonkey (JavaScript Engine)
SpiderMonkey is the first JavaScript engine, written by Brendan Eich at Netscape Communications, later released as open source and currently maintained by the Mozilla Foundation. It is still used in the Firefox web browser.
  • 3.0K
  • 07 Nov 2022
Topic Review
Sound Reduction Index
The sound reduction index is used to measure the level of sound insulation provided by a structure such as a wall, window, door, or ventilator. It is defined in the series of international standards ISO 16283 (parts 1-3) and the older ISO 140 (parts 1-14), or the regional or national variants on these standards. In the United States, the sound transmission class rating is generally used instead. The basic method for both the actual measurements and the mathematical calculations behind both standards is similar, however they diverge to a significant degree in the detail, and in the numerical results produced. Standardized methods exist for measuring the sound insulation produced by various structures in both laboratory and field (actual functional buildings and building sites) environments. A number of indexes are defined which each offer various benefits for different situations.
  • 1.5K
  • 07 Nov 2022
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