Summary

HandWiki is the world's largest wiki-style encyclopedia dedicated to science, technology and computing. It allows you to create and edit articles as long as you have external citations and login account. In addition, this is a content management environment that can be used for collaborative editing of original scholarly content, such as books, manuals, monographs and tutorials.

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List of Objects at Lagrangian Points
This is a list of known objects which occupy, have occupied, or are planned to occupy any of the five Lagrangian points of two-body systems in space.
  • 2.6K
  • 08 Nov 2022
Topic Review
SCORE
SCORE is a scorewriter program, written in FORTRAN for MS-DOS by Stanford University Professor Leland Smith (1925–2013) with a reputation for producing very high-quality results. It was widely used in engraving during the 1980s and 1990s and continues to have a small, dedicated following of engravers, many of whom regard it as the world's best music-engraving program due to its ability to position symbols precisely on the page. Several publications set using SCORE have earned Paul Revere and German Musikpresse engraving awards.
  • 2.1K
  • 08 Nov 2022
Topic Review
Paedotherium
Paedotherium is an extinct, potentially paraphyletic genus of Notoungulate, belonging to the family Hegetotheriidae, composed of small-sized, rodent or lagomorph-like South American ungulates. Four species are unambiguously recognized, from the Late Miocene to the Pleistocene of Argentina , and from the late Miocene of Bolivia and Chile .
  • 630
  • 08 Nov 2022
Topic Review
List of Sequence Alignment Software
This list of sequence alignment software is a compilation of software tools and web portals used in pairwise sequence alignment and multiple sequence alignment. See structural alignment software for structural alignment of proteins.
  • 1.4K
  • 08 Nov 2022
Topic Review
Agouti (Gene)
The agouti gene encodes the agouti-signaling protein (ASIP), responsible for the distribution of melanin pigment in mammals. Agouti interacts with the melanocortin 1 receptor to determine whether the melanocyte (pigment cell) produces phaeomelanin (a red to yellow pigment), or eumelanin (a brown to black pigment). This interaction is responsible for making distinct light and dark bands in the hairs of animals such as the agouti. In other species such as horses, the agouti gene is responsible for determining which parts of the body will be black. Horses can either have black distributed across its body or can have black only in certain locations such as the tail, ears, mane, and the lower legs. In mice, the agouti gene determines whether the animal will be yellow or grey and brown. The agouti-signaling protein (ASIP) is a competitive antagonist with alpha-Melanocyte-stimulating hormone (α-MSH) to bind with melanocortin 1 receptor (MC1R) proteins. Activation by α-MSH causes production of the darker eumelanin, while activation by ASIP causes production of the redder phaeomelanin. This means that if agouti is expressed then the phenotype will be yellow and if it's not expressed then the phenotype would be grey.
  • 2.5K
  • 08 Nov 2022
Topic Review
List of Aviation, Aerospace and Aeronautical Abbreviations
This is a list of aviation, aerospace, aeronautical and avionics abbreviations.
  • 1.2K
  • 08 Nov 2022
Topic Review
Facilitation (Business)
Facilitation in business, organizational development (OD) and consensus decision-making refers to the process of designing and running a meeting according to a previously agreed set of requirements. Facilitation concerns itself with all the tasks needed to reach a productive and impartial meeting outcome that reflects the agreed objectives and deliverables defined upfront by the meeting owner or client.
  • 567
  • 08 Nov 2022
Topic Review
Multidimensional Filter Design and Implementation
Many concepts in one–dimensional signal processing are similar to concepts in multidimensional signal processing. However, many familiar one–dimensional procedures do not readily generalize to the multidimensional case and some important issues associated with multidimensional signals and systems do not appear in the one–dimensional special case.
  • 1.4K
  • 10 Nov 2022
Topic Review
Bell's Mania
Bell's mania, also known as delirious mania, refers to an acute neurobehavioral syndrome. This is usually characterized by an expeditious onset of delirium, mania, psychosis, followed by grandiosity, emotional lability, altered consciousness, hyperthermia, and in extreme cases, death. It is sometimes misdiagnosed as excited delirium (EXD) or catatonia due to the presence of overlapping symptoms. Pathophysiology studies reveal elevated dopamine levels in the neural circuit as the underlying mechanism. Psychostimulant users as well as individuals experiencing severe manic episodes are more prone to the manifestation of this condition. Management solutions such as sedation and ketamine injections have been discussed for medical professionals and individuals with the condition. Bell's mania cases are commonly reported in countries like the United States and Canada and are commonly associated with psychostimulant use and abuse.
  • 2.3K
  • 08 Nov 2022
Topic Review
2019 in Politics and Government
Events pertaining to world affairs in 2019, national politics, public policy, government, world economics, and international business, that took place in various nations, regions, organizations, around the world in 2019.
  • 2.1K
  • 08 Nov 2022
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