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Zhong, J. Dialdehyde Cellulose. Encyclopedia. Available online: https://encyclopedia.pub/entry/61971 (accessed on 12 November 2026).
Zhong J. Dialdehyde Cellulose. Encyclopedia. Available at: https://encyclopedia.pub/entry/61971. Accessed November 12, 2026.
Zhong, Jack. "Dialdehyde Cellulose" Encyclopedia, https://encyclopedia.pub/entry/61971 (accessed November 12, 2026).
Zhong, J. (2026, November 05). Dialdehyde Cellulose. In Encyclopedia. https://encyclopedia.pub/entry/61971
Zhong, Jack. "Dialdehyde Cellulose." Encyclopedia. Web. 05 November, 2026.

Dialdehyde Cellulose

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Dialdehyde cellulose is cellulose whose anhydroglucose units carry two aldehyde groups at C2 and C3, produced by oxidative cleavage of the vicinal diols of the glucopyranose ring [1]. Cleavage opens the ring, so the product is a chain of 2,3-dialdehydic residues whose aldehyde content is expressed per anhydroglucose unit [1]. Because the aldehydes hydrate and form hemiacetals with neighbouring hydroxyls, the polymer is partly crosslinked and its crystallinity falls as oxidation proceeds [2]. The dialdehyde groups condense with amines and hydrazides to give imines and hydrazones, and that reactivity separates the material from carboxymethyl or hydroxyethyl cellulose [3]. Over-oxidation shortens the chain and introduces carboxyl groups [3].

2,3-dialdehyde cellulose periodate oxidation aldehyde content hemiacetal schiff base
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References

  1. Hashemzehi, M.; Håkansson, H.; Carlsson Kvarnlöf, G.; Henriksson, G.; Sjöstrand, B. Enzyme-Enhanced Manufacturing of Cationized Dialdehyde Cellulose. Biomacromolecules 2025, 26, 5581-5590. [CrossRef]
  2. Gao, C.; Wang, S.; Liu, B.; Yao, S.; Dai, Y.; Zhou, L.; Qin, C.; Fatehi, P. Sustainable Chitosan-Dialdehyde Cellulose Nanocrystal Film. Materials 2021, 14, 5851. [CrossRef]
  3. Kim, U.J.; Wada, M.; Kuga, S. Solubilization of dialdehyde cellulose by hot water. Carbohydrate Polymers 2004, 56, 7-10. [CrossRef]
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Update Date: 06 Nov 2026
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