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Zhong, J. Chitosan Derivatives. Encyclopedia. Available online: https://encyclopedia.pub/entry/61736 (accessed on 09 November 2026).
Zhong J. Chitosan Derivatives. Encyclopedia. Available at: https://encyclopedia.pub/entry/61736. Accessed November 09, 2026.
Zhong, Jack. "Chitosan Derivatives" Encyclopedia, https://encyclopedia.pub/entry/61736 (accessed November 09, 2026).
Zhong, J. (2026, November 02). Chitosan Derivatives. In Encyclopedia. https://encyclopedia.pub/entry/61736
Zhong, Jack. "Chitosan Derivatives." Encyclopedia. Web. 02 November, 2026.

Chitosan Derivatives

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Chitosan Derivatives are chitosans whose amino or hydroxyl groups have been substituted, grafted or quaternised, so a polymer soluble only in dilute acid becomes one whose solubility, charge and reactivity are set by the substituent. The degree and the position of substitution, on C2, C3 or C6, fix the properties more than the parent molecular weight does. Quaternisation of the amino group with glycidyltrimethylammonium chloride gives a permanently cationic chitosan that dissolves over a wider pH range [1]. Reviews of the preparation routes relate the substitution pattern to charge density and to the biological response [2]. Grafted derivatives form superabsorbent networks whose uptake follows the ionic content [3].

chitosan substitution substitution quaternary chitosan antibacterial polysaccharide superabsorbent
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References

  1. Žigrayová, D.; Mikušová, V.; Mikuš, P. Advances in Chitosan Derivatives: Preparation, Properties and Applications in Pharmacy and Medicine. Gels 2024, 10, 701. [CrossRef]
  2. Mi, Y.; Miao, Q.; Cui, J.; Tan, W.; Guo, Z. Novel 2-Hydroxypropyltrimethyl Ammonium Chitosan Derivatives: Synthesis, Characterization, Moisture Absorption and Retention Properties. Molecules 2021, 26, 4238. [CrossRef]
  3. Sorokin, A.; Lavlinskaya, M. Synthesis of the superabsobents enriched in chitosan derivatives with excellent water absorption properties. Polymer Bulletin 2022, 79, 407-427. [CrossRef]
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Subjects: Biochemistry & Molecular Biology
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Jack Zhong
View Times: 7
Entry Collection: Polymer Concepts
Revisions: 3 times (View History)
Update Date: 06 Nov 2026
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