Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Yu Peng -- 138 2026-10-25 11:13:02 |
2 delete taxonomy path Yu Peng -12 word(s) 126 2026-10-25 11:13:16 |

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
No, upload directly Yes
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Peng, Y. Genetic Recombination. Encyclopedia. Available online: https://encyclopedia.pub/entry/61429 (accessed on 12 November 2026).
Peng Y. Genetic Recombination. Encyclopedia. Available at: https://encyclopedia.pub/entry/61429. Accessed November 12, 2026.
Peng, Yu. "Genetic Recombination" Encyclopedia, https://encyclopedia.pub/entry/61429 (accessed November 12, 2026).
Peng, Y. (2026, October 25). Genetic Recombination. In Encyclopedia. https://encyclopedia.pub/entry/61429
Peng, Yu. "Genetic Recombination." Encyclopedia. Web. 25 October, 2026.

Genetic Recombination

Edit

Genetic recombination is the formation of new arrangements of genetic information through exchange or rejoining of DNA segments. Homology-directed processes can begin at DNA breaks or gaps and coordinate strand exchange with repair or renewed DNA replication [1]. Recombination proteins form nucleoprotein filaments that promote pairing of related sequences and invasion of an intact DNA duplex [2]. At the chromosome level, recombination changes associations among alleles at different loci, reshuffling the combinations transmitted to descendants. Site-specific systems act at particular recognition sequences, where recombinases cleave and reconnect DNA strands to generate integration, excision, or inversion [3][4]. The participating sequences, their orientation, and the processing of DNA intermediates determine the resulting arrangement. Regulatory interactions restrict the timing and location of these molecular reactions [5].

DNA rearrangement strand exchange recombinases genetic variation
Help expand this entry Share your expertise by adding detailed content and references to improve this entry.
Add content

References

  1. Stephen C Kowalczykowski; Initiation of genetic recombination and recombination-dependent replication. Trends Biochem. Sci. 2000, 25, 156-165. [CrossRef]
  2. Peter Baumann; Stephen C West; Role of the human RAD51 protein in homologous recombination and double-stranded-break repair. Trends Biochem. Sci. 1998, 23, 247-251. [CrossRef]
  3. N. H. Barton; B. Charlesworth; Why Sex and Recombination?. Science 1998, 281, 1986-1990. [CrossRef]
  4. Nigel D.F. Grindley; Katrine L. Whiteson; Phoebe A. Rice; Mechanisms of Site-Specific Recombination. Annu. Rev. Biochem. 2006, 75, 567-605. [CrossRef]
  5. David P. Mathiasen; Michael Lisby; Cell cycle regulation of homologous recombination inSaccharomyces cerevisiae. FEMS Microbiol. Rev. 2014, 38, 172-184. [CrossRef]
More
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.
Upload a video for this entry
Information
Subjects: Biochemistry & Molecular Biology
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Yu Peng
View Times: 11
Entry Collection: Biosynthesis and Synthetic Biology
Revisions: 2 times (View History)
Update Date: 25 Oct 2026
Table of Contents
    Notice
    You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
    OK
    Confirm
    Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
    Yes
    No
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    There is no comment~
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    ${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
    Submit
    Cancel
    Confirm
    Are you sure to Delete?
    Yes No
    Write an Entry
    Feedback