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Peng, Y. Plant Bioreactors. Encyclopedia. Available online: https://encyclopedia.pub/entry/61412 (accessed on 12 November 2026).
Peng Y. Plant Bioreactors. Encyclopedia. Available at: https://encyclopedia.pub/entry/61412. Accessed November 12, 2026.
Peng, Yu. "Plant Bioreactors" Encyclopedia, https://encyclopedia.pub/entry/61412 (accessed November 12, 2026).
Peng, Y. (2026, October 25). Plant Bioreactors. In Encyclopedia. https://encyclopedia.pub/entry/61412
Peng, Yu. "Plant Bioreactors." Encyclopedia. Web. 25 October, 2026.

Plant Bioreactors

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Plant bioreactors are controlled cultivation systems that maintain plant cells, tissues, organs, or organ-derived cultures while providing defined nutritional and physical conditions. The biological material may be suspended cells, hairy roots, shoots, embryos, or other organized structures producing biomass or specialized metabolites [1]. A plant bioreactor supplies liquid medium and regulates temperature, pH, gas exchange, mixing, and renewal of nutrients; illumination is added when photosynthetic or light-responsive material is used. Airlift, bubble-column, temporary-immersion, and mechanically agitated designs create different patterns of circulation and shear, affecting aggregation, differentiation, oxygen availability, and metabolite accumulation [2]. Plant cultures can be sensitive to mechanical stress and poor gas transfer, so vessel geometry and contact between tissue and medium must be selected carefully [1][3]. Operation may be batch, fed, or semi-continuous, with elicitors, precursors, hormones, or light changes used to redirect secondary metabolism. Evaluation includes growth rate, tissue quality, product concentration, genetic stability, contamination control, and reproducibility of harvested material [2][4].

plant cell culture hairy-root culture temporary immersion secondary metabolites
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References

  1. Shuang Zhang; Meibing Ma; Ying Liu; Heng Jiang; Jie Gao; Quan Yang; Kunhua Wei; Bioreactor Technology for Medicinal Plant In Vitro Cultures: Systems, Applications, and Future Perspectives. Biology 2026, 15, 1025. [CrossRef]
  2. Arun K. Sharma; Manoj K. Sharma; Plants as bioreactors: Recent developments and emerging opportunities. Biotechnol. Adv. 2009, 27, 811-832. [CrossRef]
  3. Maria Titova; Elena Popova; Alexander Nosov; Bioreactor Systems for Plant Cell Cultivation at the Institute of Plant Physiology of the Russian Academy of Sciences: 50 Years of Technology Evolution from Laboratory to Industrial Implications. Plants 2024, 13, 430. [CrossRef]
  4. Shuang Zhang; Meibing Ma; Ying Liu; Heng Jiang; Jie Gao; Quan Yang; Kunhua Wei; Bioreactor Technology for Medicinal Plant In Vitro Cultures: Systems, Applications, and Future Perspectives. Biology 2026, 15, 1025. [CrossRef]
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Subjects: Plant Sciences
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Yu Peng
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Update Date: 25 Oct 2026
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