Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Peter Tang + 1875 word(s) 1875 2020-12-30 02:43:04

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
No, upload directly Yes
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Tang, P. Chromosome 11. Encyclopedia. Available online: https://encyclopedia.pub/entry/6012 (accessed on 22 September 2026).
Tang P. Chromosome 11. Encyclopedia. Available at: https://encyclopedia.pub/entry/6012. Accessed September 22, 2026.
Tang, Peter. "Chromosome 11" Encyclopedia, https://encyclopedia.pub/entry/6012 (accessed September 22, 2026).
Tang, P. (2021, January 04). Chromosome 11. In Encyclopedia. https://encyclopedia.pub/entry/6012
Tang, Peter. "Chromosome 11." Encyclopedia. Web. 04 January, 2021.
Chromosome 11
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/chromosome/11

Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 11, one copy inherited from each parent, form one of the pairs.

chromosomes & mtDNA

References

  1. Abu-Amero S, Monk D, Frost J, Preece M, Stanier P, Moore GE. The geneticaetiology of Silver-Russell syndrome. J Med Genet. 2008 Apr;45(4):193-9. Epub2007 Dec 21. Review. Citation on PubMed
  2. Attiyeh EF, London WB, Mossé YP, Wang Q, Winter C, Khazi D, McGrady PW, SeegerRC, Look AT, Shimada H, Brodeur GM, Cohn SL, Matthay KK, Maris JM; Children'sOncology Group. Chromosome 1p and 11q deletions and outcome in neuroblastoma. NEngl J Med. 2005 Nov 24;353(21):2243-53. Citation on PubMed
  3. Brémond-Gignac D, Crolla JA, Copin H, Guichet A, Bonneau D, Taine L, LacombeD, Baumann C, Benzacken B, Verloes A. Combination of WAGR and Potocki-Shaffercontiguous deletion syndromes in a patient with an 11p11.2-p14 deletion. Eur JHum Genet. 2005 Apr;13(4):409-13. Citation on PubMed
  4. Choufani S, Shuman C, Weksberg R. Molecular findings in Beckwith-Wiedemannsyndrome. Am J Med Genet C Semin Med Genet. 2013 May;163C(2):131-40. doi:10.1002/ajmg.c.31363. Epub 2013 Apr 16. Review. Citation on PubMed
  5. Enklaar T, Zabel BU, Prawitt D. Beckwith-Wiedemann syndrome: multiplemolecular mechanisms. Expert Rev Mol Med. 2006 Jul 17;8(17):1-19. Review. Citation on PubMed
  6. Ensembl Human Map View
  7. Fischbach BV, Trout KL, Lewis J, Luis CA, Sika M. WAGR syndrome: a clinicalreview of 54 cases. Pediatrics. 2005 Oct;116(4):984-8. Review. Citation on PubMed
  8. Guo C, White PS, Weiss MJ, Hogarty MD, Thompson PM, Stram DO, Gerbing R,Matthay KK, Seeger RC, Brodeur GM, Maris JM. Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas. Oncogene. 1999 Sep 2;18(35):4948-57. Citation on PubMed
  9. Hall CR, Wu Y, Shaffer LG, Hecht JT. Familial case of Potocki-Shaffer syndromeassociated with microdeletion of EXT2 and ALX4. Clin Genet. 2001 Nov;60(5):356-9. Citation on PubMed
  10. Kim HG, Kim HT, Leach NT, Lan F, Ullmann R, Silahtaroglu A, Kurth I, Nowka A, Seong IS, Shen Y, Talkowski ME, Ruderfer D, Lee JH, Glotzbach C, Ha K, KjaergaardS, Levin AV, Romeike BF, Kleefstra T, Bartsch O, Elsea SH, Jabs EW, MacDonald ME,Harris DJ, Quade BJ, Ropers HH, Shaffer LG, Kutsche K, Layman LC, Tommerup N,Kalscheuer VM, Shi Y, Morton CC, Kim CH, Gusella JF. Translocations disruptingPHF21A in the Potocki-Shaffer-syndrome region are associated with intellectualdisability and craniofacial anomalies. Am J Hum Genet. 2012 Jul 13;91(1):56-72.doi: 10.1016/j.ajhg.2012.05.005. Epub 2012 Jul 5. Citation on PubMed or Free article on PubMed Central
  11. Kurahashi H, Shaikh TH, Hu P, Roe BA, Emanuel BS, Budarf ML. Regions ofgenomic instability on 22q11 and 11q23 as the etiology for the recurrentconstitutional t(11;22). Hum Mol Genet. 2000 Jul 1;9(11):1665-70. Citation on PubMed
  12. Mattina T, Perrotta CS, Grossfeld P. Jacobsen syndrome. Orphanet J Rare Dis.2009 Mar 7;4:9. doi: 10.1186/1750-1172-4-9. Review. Citation on PubMed or Free article on PubMed Central
  13. Montgomery ND, Turcott CM, Tepperberg JH, McDonald MT, Aylsworth AS. A 137-kb deletion within the Potocki-Shaffer syndrome interval on chromosome 11p11.2associated with developmental delay and hypotonia. Am J Med Genet A. 2013Jan;161A(1):198-202. doi: 10.1002/ajmg.a.35671. Epub 2012 Dec 13. Citation on PubMed
  14. Riggi N, Stamenkovic I. The Biology of Ewing sarcoma. Cancer Lett. 2007 Aug28;254(1):1-10. Epub 2007 Jan 23. Review. Citation on PubMed
  15. Romeike BF, Wuyts W. Proximal chromosome 11p contiguous gene deletion syndromephenotype: case report and review of the literature. Clin Neuropathol. 2007Jan-Feb;26(1):1-11. Review. Citation on PubMed
  16. Sankar S, Lessnick SL. Promiscuous partnerships in Ewing's sarcoma. CancerGenet. 2011 Jul;204(7):351-65. doi: 10.1016/j.cancergen.2011.07.008. Review. Citation on PubMed or Free article on PubMed Central
  17. Shaikh TH, Budarf ML, Celle L, Zackai EH, Emanuel BS. Clustered 11q23 and22q11 breakpoints and 3:1 meiotic malsegregation in multiple unrelated t(11;22)families. Am J Hum Genet. 1999 Dec;65(6):1595-607. Citation on PubMed or Free article on PubMed Central
  18. Smith AC, Choufani S, Ferreira JC, Weksberg R. Growth regulation, imprintedgenes, and chromosome 11p15.5. Pediatr Res. 2007 May;61(5 Pt 2):43R-47R. Review. Citation on PubMed
  19. Taylor TD, Noguchi H, Totoki Y, Toyoda A, Kuroki Y, Dewar K, Lloyd C, Itoh T, Takeda T, Kim DW, She X, Barlow KF, Bloom T, Bruford E, Chang JL, Cuomo CA,Eichler E, FitzGerald MG, Jaffe DB, LaButti K, Nicol R, Park HS, Seaman C,Sougnez C, Yang X, Zimmer AR, Zody MC, Birren BW, Nusbaum C, Fujiyama A, Hattori M, Rogers J, Lander ES, Sakaki Y. Human chromosome 11 DNA sequence and analysisincluding novel gene identification. Nature. 2006 Mar 23;440(7083):497-500. Citation on PubMed
  20. UCSC Genome Browser: Statistics
  21. Wakui K, Gregato G, Ballif BC, Glotzbach CD, Bailey KA, Kuo PL, Sue WC,Sheffield LJ, Irons M, Gomez EG, Hecht JT, Potocki L, Shaffer LG. Construction ofa natural panel of 11p11.2 deletions and further delineation of the criticalregion involved in Potocki-Shaffer syndrome. Eur J Hum Genet. 2005May;13(5):528-40. Citation on PubMed
  22. Wuyts W, Waeber G, Meinecke P, Schüler H, Goecke TO, Van Hul W, Bartsch O.Proximal 11p deletion syndrome (P11pDS): additional evaluation of the clinicaland molecular aspects. Eur J Hum Genet. 2004 May;12(5):400-6. Review. Citation on PubMed
  23. Xu S, Han JC, Morales A, Menzie CM, Williams K, Fan YS. Characterization of11p14-p12 deletion in WAGR syndrome by array CGH for identifying genescontributing to mental retardation and autism. Cytogenet Genome Res.2008;122(2):181-7. doi: 10.1159/000172086. Epub 2008 Dec 18. Erratum in:Cytogenet Genome Res. 2009;124(1):112. Citation on PubMed
More
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.
Upload a video for this entry
Information
Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Peter Tang
View Times: 1.2K
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 04 Jan 2021
Table of Contents
    Notice
    You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
    OK
    Confirm
    Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
    Yes
    No
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    There is no comment~
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    ${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
    Submit
    Cancel
    Confirm
    Are you sure to Delete?
    Yes No
    Academic Video Service
    Feedback