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Tang, P. Sickle Cell Disease. Encyclopedia. Available online: https://encyclopedia.pub/entry/5988 (accessed on 20 September 2026).
Tang P. Sickle Cell Disease. Encyclopedia. Available at: https://encyclopedia.pub/entry/5988. Accessed September 20, 2026.
Tang, Peter. "Sickle Cell Disease" Encyclopedia, https://encyclopedia.pub/entry/5988 (accessed September 20, 2026).
Tang, P. (2021, January 04). Sickle Cell Disease. In Encyclopedia. https://encyclopedia.pub/entry/5988
Tang, Peter. "Sickle Cell Disease." Encyclopedia. Web. 04 January, 2021.
Sickle Cell Disease
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/sickle-cell-disease

Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disease have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.

genetic conditions

References

  1. Ashley-Koch A, Yang Q, Olney RS. Sickle hemoglobin (HbS) allele and sicklecell disease: a HuGE review. Am J Epidemiol. 2000 May 1;151(9):839-45. Review. Citation on PubMed
  2. Gladwin MT, Sachdev V, Jison ML, Shizukuda Y, Plehn JF, Minter K, Brown B,Coles WA, Nichols JS, Ernst I, Hunter LA, Blackwelder WC, Schechter AN, RodgersGP, Castro O, Ognibene FP. Pulmonary hypertension as a risk factor for death inpatients with sickle cell disease. N Engl J Med. 2004 Feb 26;350(9):886-95. Citation on PubMed
  3. Powars DR, Chan LS, Hiti A, Ramicone E, Johnson C. Outcome of sickle cellanemia: a 4-decade observational study of 1056 patients. Medicine (Baltimore).2005 Nov;84(6):363-76. Citation on PubMed
  4. Schnog JB, Duits AJ, Muskiet FA, ten Cate H, Rojer RA, Brandjes DP. Sicklecell disease; a general overview. Neth J Med. 2004 Nov;62(10):364-74. Review. Citation on PubMed
  5. Serjeant GR. The emerging understanding of sickle cell disease. Br J Haematol.2001 Jan;112(1):3-18. Review. Citation on PubMed
  6. Stuart MJ, Nagel RL. Sickle-cell disease. Lancet. 2004 Oct9-15;364(9442):1343-60. Review. Citation on PubMed
  7. Vichinsky E. New therapies in sickle cell disease. Lancet. 2002 Aug24;360(9333):629-31. Review. Citation on PubMed
  8. Vichinsky EP. Pulmonary hypertension in sickle cell disease. N Engl J Med.2004 Feb 26;350(9):857-9. Citation on PubMed
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Peter Tang
View Times: 1.3K
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 04 Jan 2021
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