Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Peter Tang + 735 word(s) 735 2020-12-30 02:33:35

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
No, upload directly Yes
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Tang, P. Intervertebral Disc Disease. Encyclopedia. Available online: https://encyclopedia.pub/entry/5945 (accessed on 25 September 2026).
Tang P. Intervertebral Disc Disease. Encyclopedia. Available at: https://encyclopedia.pub/entry/5945. Accessed September 25, 2026.
Tang, Peter. "Intervertebral Disc Disease" Encyclopedia, https://encyclopedia.pub/entry/5945 (accessed September 25, 2026).
Tang, P. (2020, December 31). Intervertebral Disc Disease. In Encyclopedia. https://encyclopedia.pub/entry/5945
Tang, Peter. "Intervertebral Disc Disease." Encyclopedia. Web. 31 December, 2020.
Intervertebral Disc Disease
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/intervertebral-disc-disease

Intervertebral disc disease is a common condition characterized by the breakdown (degeneration) of one or more of the discs that separate the bones of the spine (vertebrae), causing pain in the back or neck and frequently in the legs and arms. The intervertebral discs provide cushioning between vertebrae and absorb pressure put on the spine.

genetic conditions

References

  1. Feng Y, Egan B, Wang J. Genetic Factors in Intervertebral Disc Degeneration.Genes Dis. 2016 Sep;3(3):178-185. Epub 2016 Apr 23. Citation on PubMed or Free article on PubMed Central
  2. Hanaei S, Abdollahzade S, Khoshnevisan A, Kepler CK, Rezaei N. Genetic aspectsof intervertebral disc degeneration. Rev Neurosci. 2015;26(5):581-606. doi:10.1515/revneuro-2014-0077. Review. Citation on PubMed
  3. Ikegawa S. The genetics of common degenerative skeletal disorders:osteoarthritis and degenerative disc disease. Annu Rev Genomics Hum Genet.2013;14:245-56. doi: 10.1146/annurev-genom-091212-153427. Review. Citation on PubMed
  4. Janeczko Ł, Janeczko M, Chrzanowski R, Zieliński G. The role of polymorphisms of genes encoding collagen IX and XI in lumbar disc disease. Neurol NeurochirPol. 2014 Jan-Feb;48(1):60-2. doi: 10.1016/j.pjnns.2013.04.001. Epub 2014 Jan 23.Review. Citation on PubMed
  5. Kalb S, Martirosyan NL, Kalani MY, Broc GG, Theodore N. Genetics of thedegenerated intervertebral disc. World Neurosurg. 2012 Mar-Apr;77(3-4):491-501.doi: 10.1016/j.wneu.2011.07.014. Epub 2011 Nov 7. Review. Citation on PubMed
  6. Kepler CK, Ponnappan RK, Tannoury CA, Risbud MV, Anderson DG. The molecularbasis of intervertebral disc degeneration. Spine J. 2013 Mar;13(3):318-30. doi:10.1016/j.spinee.2012.12.003. Epub 2013 Feb 8. Review. Citation on PubMed
  7. Toktaş ZO, Ekşi MŞ, Yılmaz B, Demir MK, Özgen S, Kılıç T, Konya D. Associationof collagen I, IX and vitamin D receptor gene polymorphisms with radiologicalseverity of intervertebral disc degeneration in Southern European Ancestor. EurSpine J. 2015 Nov;24(11):2432-41. doi: 10.1007/s00586-015-4206-5. Epub 2015 Sep5. Citation on PubMed
  8. Zhang Y, Sun Z, Liu J, Guo X. Advances in susceptibility genetics ofintervertebral degenerative disc disease. Int J Biol Sci. 2008 Sep 2;4(5):283-90.Review. Citation on PubMed or Free article on PubMed Central
More
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.
Upload a video for this entry
Information
Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Peter Tang
View Times: 1.1K
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 31 Dec 2020
Table of Contents
    Notice
    You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
    OK
    Confirm
    Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
    Yes
    No
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    There is no comment~
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    ${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
    Submit
    Cancel
    Confirm
    Are you sure to Delete?
    Yes No
    Academic Video Service
    Feedback