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Tang, P. Gorlin Syndrome. Encyclopedia. Available online: https://encyclopedia.pub/entry/5940 (accessed on 21 September 2026).
Tang P. Gorlin Syndrome. Encyclopedia. Available at: https://encyclopedia.pub/entry/5940. Accessed September 21, 2026.
Tang, Peter. "Gorlin Syndrome" Encyclopedia, https://encyclopedia.pub/entry/5940 (accessed September 21, 2026).
Tang, P. (2020, December 31). Gorlin Syndrome. In Encyclopedia. https://encyclopedia.pub/entry/5940
Tang, Peter. "Gorlin Syndrome." Encyclopedia. Web. 31 December, 2020.
Gorlin Syndrome
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/gorlin-syndrome

Gorlin syndrome, also known as nevoid basal cell carcinoma syndrome, is a condition that affects many areas of the body and increases the risk of developing various cancerous and noncancerous tumors.

genetic conditions

References

  1. Bale AE, Yu KP. The hedgehog pathway and basal cell carcinomas. Hum Mol Genet.2001 Apr;10(7):757-62. Review. Citation on PubMed
  2. Evans DG, Farndon PA. Nevoid Basal Cell Carcinoma Syndrome. 2002 Jun 20[updated 2018 Mar 29]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): Universityof Washington, Seattle; 1993-2020. Available fromhttp://www.ncbi.nlm.nih.gov/books/NBK1151/ Citation on PubMed
  3. Evans DG, Howard E, Giblin C, Clancy T, Spencer H, Huson SM, Lalloo F. Birthincidence and prevalence of tumor-prone syndromes: estimates from a UK familygenetic register service. Am J Med Genet A. 2010 Feb;152A(2):327-32. doi:10.1002/ajmg.a.33139. Citation on PubMed
  4. Gorlin RJ. Nevoid basal cell carcinoma (Gorlin) syndrome. Genet Med. 2004Nov-Dec;6(6):530-9. Review. Citation on PubMed
  5. Guenther LC, Barber K, Searles GE, Lynde CW, Janiszewski P, Ashkenas J;Canadian Non-melanoma Skin Cancer Guidelines Committee. Non-melanoma Skin Cancer in Canada Chapter 1: Introduction to the Guidelines. J Cutan Med Surg. 2015May-Jun;19(3):205-15. doi: 10.1177/1203475415588652. Epub 2015 May 27. Erratumin: J Cutan Med Surg. 2015 Nov-Dec;19(6):604. Citation on PubMed
  6. High A, Zedan W. Basal cell nevus syndrome. Curr Opin Oncol. 2005Mar;17(2):160-6. Review. Citation on PubMed
  7. Lo Muzio L, Pastorino L, Levanat S, Musani V, Situm M, Scarra GB. Clinicalutility gene card for: Gorlin syndrome. Eur J Hum Genet. 2011 Aug;19(8). doi:10.1038/ejhg.2011.9. Epub 2011 Feb 9. Citation on PubMed or Free article on PubMed Central
  8. Madras J, Lapointe H. Keratocystic odontogenic tumour: reclassification of theodontogenic keratocyst from cyst to tumour. J Can Dent Assoc. 2008Mar;74(2):165-165h. Citation on PubMed
  9. Muller EA, Aradhya S, Atkin JF, Carmany EP, Elliott AM, Chudley AE, Clark RD, Everman DB, Garner S, Hall BD, Herman GE, Kivuva E, Ramanathan S, Stevenson DA,Stockton DW, Hudgins L. Microdeletion 9q22.3 syndrome includes metopiccraniosynostosis, hydrocephalus, macrosomia, and developmental delay. Am J MedGenet A. 2012 Feb;158A(2):391-9. doi: 10.1002/ajmg.a.34216. Epub 2011 Dec 21. Citation on PubMed
  10. Smith MJ, Beetz C, Williams SG, Bhaskar SS, O'Sullivan J, Anderson B, Daly SB,Urquhart JE, Bholah Z, Oudit D, Cheesman E, Kelsey A, McCabe MG, Newman WG, EvansDG. Germline mutations in SUFU cause Gorlin syndrome-associated childhoodmedulloblastoma and redefine the risk associated with PTCH1 mutations. J ClinOncol. 2014 Dec 20;32(36):4155-61. doi: 10.1200/JCO.2014.58.2569. Epub 2014 Nov17. Citation on PubMed
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Peter Tang
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Entry Collection: MedlinePlus
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Update Date: 31 Dec 2020
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