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Tang, P. Brugada Syndrome. Encyclopedia. Available online: https://encyclopedia.pub/entry/5936 (accessed on 21 September 2026).
Tang P. Brugada Syndrome. Encyclopedia. Available at: https://encyclopedia.pub/entry/5936. Accessed September 21, 2026.
Tang, Peter. "Brugada Syndrome" Encyclopedia, https://encyclopedia.pub/entry/5936 (accessed September 21, 2026).
Tang, P. (2020, December 31). Brugada Syndrome. In Encyclopedia. https://encyclopedia.pub/entry/5936
Tang, Peter. "Brugada Syndrome." Encyclopedia. Web. 31 December, 2020.
Brugada Syndrome
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/brugada-syndrome

Brugada syndrome is a condition that causes a disruption of the heart's normal rhythm. Specifically, this disorder can lead to irregular heartbeats in the heart's lower chambers (ventricles), which is an abnormality called ventricular arrhythmia. If untreated, the irregular heartbeats can cause fainting (syncope), seizures, difficulty breathing, or sudden death. These complications typically occur when an affected person is resting or asleep.

genetic conditions

References

  1. Antzelevitch C, Brugada P, Borggrefe M, Brugada J, Brugada R, Corrado D,Gussak I, LeMarec H, Nademanee K, Perez Riera AR, Shimizu W, Schulze-Bahr E, Tan H, Wilde A. Brugada syndrome: report of the second consensus conference. HeartRhythm. 2005 Apr;2(4):429-40. Review. Erratum in: Heart Rhythm. 2005Aug;2(8):905. Citation on PubMed
  2. Antzelevitch C. Brugada syndrome: clinical, genetic, molecular, cellular andionic aspects. Expert Rev Cardiovasc Ther. 2003 Jul;1(2):177-85. Review. Citation on PubMed
  3. Brugada P, Brugada J. Right bundle branch block, persistent ST segmentelevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol. 1992 Nov 15;20(6):1391-6. Citation on PubMed
  4. Brugada R, Campuzano O, Sarquella-Brugada G, Brugada J, Brugada P. Brugadasyndrome. Methodist Debakey Cardiovasc J. 2014 Jan-Mar;10(1):25-8. Review. Citation on PubMed or Free article on PubMed Central
  5. Brugada R, Campuzano O, Sarquella-Brugada G, Brugada P, Brugada J, Hong K.Brugada Syndrome. 2005 Mar 31 [updated 2016 Nov 17]. In: Adam MP, Ardinger HH,Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews®[Internet]. Seattle (WA): University of Washington, Seattle; 1993-2020. Availablefrom http://www.ncbi.nlm.nih.gov/books/NBK1517/ Citation on PubMed
  6. Crotti L, Marcou CA, Tester DJ, Castelletti S, Giudicessi JR, Torchio M,Medeiros-Domingo A, Simone S, Will ML, Dagradi F, Schwartz PJ, Ackerman MJ.Spectrum and prevalence of mutations involving BrS1- through BrS12-susceptibilitygenes in a cohort of unrelated patients referred for Brugada syndrome genetictesting: implications for genetic testing. J Am Coll Cardiol. 2012 Oct9;60(15):1410-8. doi: 10.1016/j.jacc.2012.04.037. Epub 2012 Jul 25. Citation on PubMed or Free article on PubMed Central
  7. Francis J, Antzelevitch C. Brugada syndrome. Int J Cardiol. 2005 May25;101(2):173-8. Review. Citation on PubMed or Free article on PubMed Central
  8. Juang JM, Huang SK. Brugada syndrome--an under-recognized electrical diseasein patients with sudden cardiac death. Cardiology. 2004;101(4):157-69. Epub 2004 Feb 12. Review. Citation on PubMed
  9. Le Scouarnec S, Karakachoff M, Gourraud JB, Lindenbaum P, Bonnaud S, PorteroV, Duboscq-Bidot L, Daumy X, Simonet F, Teusan R, Baron E, Violleau J, Persyn E, Bellanger L, Barc J, Chatel S, Martins R, Mabo P, Sacher F, Haïssaguerre M, KyndtF, Schmitt S, Bézieau S, Le Marec H, Dina C, Schott JJ, Probst V, Redon R.Testing the burden of rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for Brugada syndrome. Hum Mol Genet. 2015May 15;24(10):2757-63. doi: 10.1093/hmg/ddv036. Epub 2015 Feb 3. Citation on PubMed
  10. Li A, Behr ER. Brugada syndrome: an update. Future Cardiol. 2013Mar;9(2):253-71. doi: 10.2217/fca.12.82. Review. Citation on PubMed
  11. Modell SM, Lehmann MH. The long QT syndrome family of cardiac ionchannelopathies: a HuGE review. Genet Med. 2006 Mar;8(3):143-55. Review. Citation on PubMed
  12. Shimizu W, Aiba T, Kamakura S. Mechanisms of disease: current understandingand future challenges in Brugada syndrome. Nat Clin Pract Cardiovasc Med. 2005Aug;2(8):408-14. Review. Citation on PubMed
  13. Shimizu W. Acquired forms of the Brugada syndrome. J Electrocardiol. 2005Oct;38(4 Suppl):22-5. Review. Citation on PubMed
  14. Vatta M, Dumaine R, Varghese G, Richard TA, Shimizu W, Aihara N, Nademanee K, Brugada R, Brugada J, Veerakul G, Li H, Bowles NE, Brugada P, Antzelevitch C,Towbin JA. Genetic and biophysical basis of sudden unexplained nocturnal deathsyndrome (SUNDS), a disease allelic to Brugada syndrome. Hum Mol Genet. 2002 Feb 1;11(3):337-45. Citation on PubMed
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Peter Tang
View Times: 982
Entry Collection: MedlinePlus
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Update Date: 31 Dec 2020
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