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Li, V. FLG Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/5537 (accessed on 21 September 2026).
Li V. FLG Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/5537. Accessed September 21, 2026.
Li, Vivi. "FLG Gene" Encyclopedia, https://encyclopedia.pub/entry/5537 (accessed September 21, 2026).
Li, V. (2020, December 25). FLG Gene. In Encyclopedia. https://encyclopedia.pub/entry/5537
Li, Vivi. "FLG Gene." Encyclopedia. Web. 25 December, 2020.
FLG Gene
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/flg

Filaggrin

genes

References

  1. Brown SJ, McLean WH. One remarkable molecule: filaggrin. J Invest Dermatol.2012 Mar;132(3 Pt 2):751-62. doi: 10.1038/jid.2011.393.
  2. Irvine AD, McLean WH, Leung DY. Filaggrin mutations associated with skin andallergic diseases. N Engl J Med. 2011 Oct 6;365(14):1315-27. doi:10.1056/NEJMra1011040. Review.
  3. Liang Y, Chang C, Lu Q. The Genetics and Epigenetics of AtopicDermatitis-Filaggrin and Other Polymorphisms. Clin Rev Allergy Immunol. 2016Dec;51(3):315-328. Review.
  4. Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR,Sandilands A, Campbell LE, Smith FJ, O'Regan GM, Watson RM, Cecil JE, Bale SJ,Compton JG, DiGiovanna JJ, Fleckman P, Lewis-Jones S, Arseculeratne G, SergeantA, Munro CS, El Houate B, McElreavey K, Halkjaer LB, Bisgaard H, Mukhopadhyay S, McLean WH. Common loss-of-function variants of the epidermal barrier proteinfilaggrin are a major predisposing factor for atopic dermatitis. Nat Genet. 2006 Apr;38(4):441-6.
  5. Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ,Irvine AD, Weidinger S. Meta-analysis of filaggrin polymorphisms in eczema andasthma: robust risk factors in atopic disease. J Allergy Clin Immunol. 2009Jun;123(6):1361-70.e7. doi: 10.1016/j.jaci.2009.03.036.
  6. Smith FJ, Irvine AD, Terron-Kwiatkowski A, Sandilands A, Campbell LE, Zhao Y, Liao H, Evans AT, Goudie DR, Lewis-Jones S, Arseculeratne G, Munro CS, SergeantA, O'Regan G, Bale SJ, Compton JG, DiGiovanna JJ, Presland RB, Fleckman P, McLeanWH. Loss-of-function mutations in the gene encoding filaggrin cause ichthyosisvulgaris. Nat Genet. 2006 Mar;38(3):337-42.
  7. Thyssen JP, Godoy-Gijon E, Elias PM. Ichthyosis vulgaris: the filaggrinmutation disease. Br J Dermatol. 2013 Jun;168(6):1155-66. doi: 10.1111/bjd.12219.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 1.1K
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 25 Dec 2020
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