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Li, V. EDN3 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/5266 (accessed on 22 September 2026).
Li V. EDN3 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/5266. Accessed September 22, 2026.
Li, Vivi. "EDN3 Gene" Encyclopedia, https://encyclopedia.pub/entry/5266 (accessed September 22, 2026).
Li, V. (2020, December 24). EDN3 Gene. In Encyclopedia. https://encyclopedia.pub/entry/5266
Li, Vivi. "EDN3 Gene." Encyclopedia. Web. 24 December, 2020.
EDN3 Gene
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/edn3

Endothelin 3: The EDN3 gene provides instructions for making a protein called endothelin 3. 

genes

References

  1. Baynash AG, Hosoda K, Giaid A, Richardson JA, Emoto N, Hammer RE, YanagisawaM. Interaction of endothelin-3 with endothelin-B receptor is essential fordevelopment of epidermal melanocytes and enteric neurons. Cell. 1994 Dec30;79(7):1277-85.
  2. Duan XL, Zhang XS, Li GW. Clinical relationship between EDN-3 gene, EDNRB geneand Hirschsprung's disease. World J Gastroenterol. 2003 Dec;9(12):2839-42.
  3. Gazquez E, Watanabe Y, Broders-Bondon F, Paul-Gilloteaux P, Heysch J, Baral V,Bondurand N, Dufour S. Endothelin-3 stimulates cell adhesion and cooperates with β1-integrins during enteric nervous system ontogenesis. Sci Rep. 2016 Dec1;6:37877. doi: 10.1038/srep37877.
  4. Heuckeroth RO. Finding your way to the end: a tale of GDNF and endothelin-3.Neuron. 2003 Dec 4;40(5):871-3. Review.
  5. Kapur RP, Gershon MD, Milla PJ, Pachnis V. The influence of Hox genes andthree intercellular signalling pathways on enteric neuromuscular development.Neurogastroenterol Motil. 2004 Apr;16 Suppl 1:8-13. Review.
  6. Pingault V, Bondurand N, Lemort N, Sancandi M, Ceccherini I, Hugot JP, JoukPS, Goossens M. A heterozygous endothelin 3 mutation in Waardenburg-Hirschsprung disease: is there a dosage effect of EDN3/EDNRB gene mutations onneurocristopathy phenotypes? J Med Genet. 2001 Mar;38(3):205-9.
  7. Shin MK, Levorse JM, Ingram RS, Tilghman SM. The temporal requirement forendothelin receptor-B signalling during neural crest development. Nature. 1999Dec 2;402(6761):496-501.
  8. Svensson PJ, Von Tell D, Molander ML, Anvret M, Nordenskjöld A. A heterozygousframeshift mutation in the endothelin-3 (EDN-3) gene in isolated Hirschsprung'sdisease. Pediatr Res. 1999 May;45(5 Pt 1):714-7.
  9. Sánchez-Mejías A, Fernández RM, López-Alonso M, Antiñolo G, Borrego S. Newroles of EDNRB and EDN3 in the pathogenesis of Hirschsprung disease. Genet Med.2010 Jan;12(1):39-43. doi: 10.1097/GIM.0b013e3181c371b0.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 880
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 24 Dec 2020
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