EDA Gene

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Li, V. EDA Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/5246 (accessed on 22 September 2026).

Li V. EDA Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/5246. Accessed September 22, 2026.

Li, Vivi. "EDA Gene" Encyclopedia, https://encyclopedia.pub/entry/5246 (accessed September 22, 2026).

Li, V. (2020, December 24). EDA Gene. In Encyclopedia. https://encyclopedia.pub/entry/5246

Li, Vivi. "EDA Gene." Encyclopedia. Web. 24 December, 2020.

EDA Gene

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/eda

Ectodysplasin A: The EDA gene provides instructions for making a protein called ectodysplasin A.

genes

References

Cluzeau C, Hadj-Rabia S, Jambou M, Mansour S, Guigue P, Masmoudi S, Bal E,Chassaing N, Vincent MC, Viot G, Clauss F, Manière MC, Toupenay S, Le Merrer M,Lyonnet S, Cormier-Daire V, Amiel J, Faivre L, de Prost Y, Munnich A, BonnefontJP, Bodemer C, Smahi A. Only four genes (EDA1, EDAR, EDARADD, and WNT10A) accountfor 90% of hypohidrotic/anhidrotic ectodermal dysplasia cases. Hum Mutat. 2011Jan;32(1):70-2. doi: 10.1002/humu.21384.
Han D, Gong Y, Wu H, Zhang X, Yan M, Wang X, Qu H, Feng H, Song S. Novel EDAmutation resulting in X-linked non-syndromic hypodontia and the pattern ofEDA-associated isolated tooth agenesis. Eur J Med Genet. 2008Nov-Dec;51(6):536-46. doi: 10.1016/j.ejmg.2008.06.002.
Kowalczyk-Quintas C, Schneider P. Ectodysplasin A (EDA) - EDA receptorsignalling and its pharmacological modulation. Cytokine Growth Factor Rev. 2014Apr;25(2):195-203. doi: 10.1016/j.cytogfr.2014.01.004.
Song S, Han D, Qu H, Gong Y, Wu H, Zhang X, Zhong N, Feng H. EDA genemutations underlie non-syndromic oligodontia. J Dent Res. 2009 Feb;88(2):126-31. doi: 10.1177/0022034508328627.
Tarpey P, Pemberton TJ, Stockton DW, Das P, Ninis V, Edkins S, Andrew Futreal P, Wooster R, Kamath S, Nayak R, Stratton MR, Patel PI. A novel Gln358Glumutation in ectodysplasin A associated with X-linked dominant incisor hypodontia.Am J Med Genet A. 2007 Feb 15;143(4):390-4.
Vincent MC, Biancalana V, Ginisty D, Mandel JL, Calvas P. Mutational spectrum of the ED1 gene in X-linked hypohidrotic ectodermal dysplasia. Eur J Hum Genet.2001 May;9(5):355-63.
Wiśniewski SA, Kobielak A, Trzeciak WH, Kobielak K. Recent advances inunderstanding of the molecular basis of anhidrotic ectodermal dysplasia:discovery of a ligand, ectodysplasin A and its two receptors. J Appl Genet.2002;43(1):97-107. Review.
Wohlfart S, Hammersen J, Schneider H. Mutational spectrum in 101 patients withhypohidrotic ectodermal dysplasia and breakpoint mapping in independent cases of rare genomic rearrangements. J Hum Genet. 2016 Oct;61(10):891-897. doi:10.1038/jhg.2016.75.
Wright JT, Grange DK, Fete M. Hypohidrotic Ectodermal Dysplasia. 2003 Apr 28[updated 2017 Jun 1]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH,Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): Universityof Washington, Seattle; 1993-2020. Available fromhttp://www.ncbi.nlm.nih.gov/books/NBK1112/

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Subjects: Genetics & Heredity

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Update Date: 24 Dec 2020

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