Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Catherine Yang + 526 word(s) 526 2020-12-15 07:18:19

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
No, upload directly Yes
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Yang, C. CHMP2B-Related Frontotemporal Dementia. Encyclopedia. Available online: https://encyclopedia.pub/entry/5067 (accessed on 21 September 2026).
Yang C. CHMP2B-Related Frontotemporal Dementia. Encyclopedia. Available at: https://encyclopedia.pub/entry/5067. Accessed September 21, 2026.
Yang, Catherine. "CHMP2B-Related Frontotemporal Dementia" Encyclopedia, https://encyclopedia.pub/entry/5067 (accessed September 21, 2026).
Yang, C. (2020, December 24). CHMP2B-Related Frontotemporal Dementia. In Encyclopedia. https://encyclopedia.pub/entry/5067
Yang, Catherine. "CHMP2B-Related Frontotemporal Dementia." Encyclopedia. Web. 24 December, 2020.
CHMP2B-Related Frontotemporal Dementia
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/chmp2b-related-frontotemporal-dementia

CHMP2B-related frontotemporal dementia is a progressive brain disorder that affects personality, behavior, and language. The symptoms of this disorder usually become noticeable in a person's fifties or sixties, and affected people survive about 3 to 21 years after the appearance of symptoms.

genetic conditions

References

  1. Brown J, Ashworth A, Gydesen S, Sorensen A, Rossor M, Hardy J, Collinge J.Familial non-specific dementia maps to chromosome 3. Hum Mol Genet. 1995Sep;4(9):1625-8.
  2. Brown J, Gydesen S, Johannsen P, Gade A, Skibinski G, Chakrabarti L, Brun A,Spillantini M, Yancopoulou D, Thusgaard T, Sorensen A, Fisher E, Collinge J;FReJA (Frontotemporal Dementia Research in Jutland Association). Frontotemporaldementia linked to chromosome 3. Dement Geriatr Cogn Disord. 2004;17(4):274-6.
  3. Brown J. Chromosome 3-linked frontotemporal dementia. Cell Mol Life Sci. 1998 Sep;54(9):925-7. Review.
  4. Gydesen S, Brown JM, Brun A, Chakrabarti L, Gade A, Johannsen P, Rossor M,Thusgaard T, Grove A, Yancopoulou D, Spillantini MG, Fisher EM, Collinge J,Sorensen SA. Chromosome 3 linked frontotemporal dementia (FTD-3). Neurology. 2002Nov 26;59(10):1585-94.
  5. Holm IE, Englund E, Mackenzie IR, Johannsen P, Isaacs AM. A reassessment ofthe neuropathology of frontotemporal dementia linked to chromosome 3. JNeuropathol Exp Neurol. 2007 Oct;66(10):884-91.
  6. Lindquist SG, Braedgaard H, Svenstrup K, Isaacs AM, Nielsen JE; FReJAConsortium. Frontotemporal dementia linked to chromosome 3 (FTD-3)--currentconcepts and the detection of a previously unknown branch of the Danish FTD-3family. Eur J Neurol. 2008 Jul;15(7):667-70. doi:10.1111/j.1468-1331.2008.02144.x.
  7. Roos P, Holm IE, Nielsen JE, Nielsen TT, Brown JM, Johannsen P, Isaacs AM.CHMP2B Frontotemporal Dementia. 2007 Aug 23 [updated 2020 Jul 2]. In: Adam MP,Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors.GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle;1993-2020. Available from http://www.ncbi.nlm.nih.gov/books/NBK1199/
  8. Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, Hummerich H,Nielsen JE, Hodges JR, Spillantini MG, Thusgaard T, Brandner S, Brun A, RossorMN, Gade A, Johannsen P, Sørensen SA, Gydesen S, Fisher EM, Collinge J. Mutationsin the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. Nat Genet. 2005 Aug;37(8):806-8.
  9. van der Zee J, Urwin H, Engelborghs S, Bruyland M, Vandenberghe R, Dermaut B, De Pooter T, Peeters K, Santens P, De Deyn PP, Fisher EM, Collinge J, Isaacs AM, Van Broeckhoven C. CHMP2B C-truncating mutations in frontotemporal lobardegeneration are associated with an aberrant endosomal phenotype in vitro. HumMol Genet. 2008 Jan 15;17(2):313-22.
More
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.
Upload a video for this entry
Information
Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Catherine Yang
View Times: 927
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 24 Dec 2020
Table of Contents
    Notice
    You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
    OK
    Confirm
    Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
    Yes
    No
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    There is no comment~
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    ${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
    Submit
    Cancel
    Confirm
    Are you sure to Delete?
    Yes No
    Academic Video Service
    Feedback