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| 1 | Catherine Yang | + 778 word(s) | 778 | 2020-12-15 07:18:10 |
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Yang, C. C3 Glomerulopathy. Encyclopedia. Available online: https://encyclopedia.pub/entry/5044 (accessed on 22 September 2026).
Yang C. C3 Glomerulopathy. Encyclopedia. Available at: https://encyclopedia.pub/entry/5044. Accessed September 22, 2026.
Yang, Catherine. "C3 Glomerulopathy" Encyclopedia, https://encyclopedia.pub/entry/5044 (accessed September 22, 2026).
Yang, C. (2020, December 24). C3 Glomerulopathy. In Encyclopedia. https://encyclopedia.pub/entry/5044
Yang, Catherine. "C3 Glomerulopathy." Encyclopedia. Web. 24 December, 2020.
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C3 glomerulopathy is a group of related conditions that cause the kidneys to malfunction. The major features of C3 glomerulopathy include high levels of protein in the urine (proteinuria), blood in the urine (hematuria), reduced amounts of urine, low levels of protein in the blood, and swelling in many areas of the body. Affected individuals may have particularly low levels of a protein called complement component 3 (or C3) in the blood.
genetic conditions
References
- Abrera-Abeleda MA, Nishimura C, Frees K, Jones M, Maga T, Katz LM, Zhang Y,Smith RJ. Allelic variants of complement genes associated with dense depositdisease. J Am Soc Nephrol. 2011 Aug;22(8):1551-9. doi: 10.1681/ASN.2010080795.
- Barbour TD, Ruseva MM, Pickering MC. Update on C3 glomerulopathy. Nephrol DialTransplant. 2016 May;31(5):717-25. doi: 10.1093/ndt/gfu317.Review.
- Bu F, Borsa NG, Jones MB, Takanami E, Nishimura C, Hauer JJ, Azaiez H,Black-Ziegelbein EA, Meyer NC, Kolbe DL, Li Y, Frees K, Schnieders MJ, Thomas C, Nester C, Smith RJ. High-Throughput Genetic Testing for ThromboticMicroangiopathies and C3 Glomerulopathies. J Am Soc Nephrol. 2016Apr;27(4):1245-53. doi: 10.1681/ASN.2015040385.
- Fakhouri F, Frémeaux-Bacchi V, Noël LH, Cook HT, Pickering MC. C3glomerulopathy: a new classification. Nat Rev Nephrol. 2010 Aug;6(8):494-9. doi: 10.1038/nrneph.2010.85.
- Martín B, Smith RJH. C3 Glomerulopathy. 2007 Jul 20 [updated 2018 Apr 5]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A,editors. GeneReviews® [Internet]. Seattle (WA): University of Washington,Seattle; 1993-2020. Available from http://www.ncbi.nlm.nih.gov/books/NBK1425/
- Medjeral-Thomas NR, O'Shaughnessy MM, O'Regan JA, Traynor C, Flanagan M, Wong L, Teoh CW, Awan A, Waldron M, Cairns T, O'Kelly P, Dorman AM, Pickering MC,Conlon PJ, Cook HT. C3 glomerulopathy: clinicopathologic features and predictors of outcome. Clin J Am Soc Nephrol. 2014 Jan;9(1):46-53. doi:10.2215/CJN.04700513.
- Pickering MC, D'Agati VD, Nester CM, Smith RJ, Haas M, Appel GB, Alpers CE,Bajema IM, Bedrosian C, Braun M, Doyle M, Fakhouri F, Fervenza FC, Fogo AB,Frémeaux-Bacchi V, Gale DP, Goicoechea de Jorge E, Griffin G, Harris CL, HolersVM, Johnson S, Lavin PJ, Medjeral-Thomas N, Paul Morgan B, Nast CC, Noel LH,Peters DK, Rodríguez de Córdoba S, Servais A, Sethi S, Song WC, Tamburini P,Thurman JM, Zavros M, Cook HT. C3 glomerulopathy: consensus report. Kidney Int.2013 Dec;84(6):1079-89. doi: 10.1038/ki.2013.377.
- Servais A, Noël LH, Roumenina LT, Le Quintrec M, Ngo S, Dragon-Durey MA,Macher MA, Zuber J, Karras A, Provot F, Moulin B, Grünfeld JP, Niaudet P, LesavreP, Frémeaux-Bacchi V. Acquired and genetic complement abnormalities play acritical role in dense deposit disease and other C3 glomerulopathies. Kidney Int.2012 Aug;82(4):454-64. doi: 10.1038/ki.2012.63.
- Xiao X, Pickering MC, Smith RJ. C3 glomerulopathy: the genetic and clinicalfindings in dense deposit disease and C3 glomerulonephritis. Semin Thromb Hemost.2014 Jun;40(4):465-71. doi: 10.1055/s-0034-1376334.
- Zipfel PF, Skerka C, Chen Q, Wiech T, Goodship T, Johnson S, Fremeaux-BacchiV, Nester C, de Córdoba SR, Noris M, Pickering M, Smith R. The role of complementin C3 glomerulopathy. Mol Immunol. 2015 Sep;67(1):21-30. doi:10.1016/j.molimm.2015.03.012.
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