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Li, V. DUX4 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/5000 (accessed on 22 September 2026).
Li V. DUX4 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/5000. Accessed September 22, 2026.
Li, Vivi. "DUX4 Gene" Encyclopedia, https://encyclopedia.pub/entry/5000 (accessed September 22, 2026).
Li, V. (2020, December 24). DUX4 Gene. In Encyclopedia. https://encyclopedia.pub/entry/5000
Li, Vivi. "DUX4 Gene." Encyclopedia. Web. 24 December, 2020.
DUX4 Gene
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/dux4

Double Homeobox 4

genes

References

  1. Geng LN, Yao Z, Snider L, Fong AP, Cech JN, Young JM, van der Maarel SM, RuzzoWL, Gentleman RC, Tawil R, Tapscott SJ. DUX4 activates germline genes,retroelements, and immune mediators: implications for facioscapulohumeraldystrophy. Dev Cell. 2012 Jan 17;22(1):38-51. doi: 10.1016/j.devcel.2011.11.013.
  2. Lemmers RJ, Tawil R, Petek LM, Balog J, Block GJ, Santen GW, Amell AM, van derVliet PJ, Almomani R, Straasheijm KR, Krom YD, Klooster R, Sun Y, den Dunnen JT, Helmer Q, Donlin-Smith CM, Padberg GW, van Engelen BG, de Greef JC, Aartsma-RusAM, Frants RR, de Visser M, Desnuelle C, Sacconi S, Filippova GN, Bakker B,Bamshad MJ, Tapscott SJ, Miller DG, van der Maarel SM. Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeralmuscular dystrophy type 2. Nat Genet. 2012 Dec;44(12):1370-4. doi:10.1038/ng.2454.
  3. Lemmers RJ, van der Vliet PJ, Klooster R, Sacconi S, Camaño P, Dauwerse JG,Snider L, Straasheijm KR, van Ommen GJ, Padberg GW, Miller DG, Tapscott SJ, TawilR, Frants RR, van der Maarel SM. A unifying genetic model for facioscapulohumeralmuscular dystrophy. Science. 2010 Sep 24;329(5999):1650-3. doi:10.1126/science.1189044.
  4. Sacconi S, Salviati L, Desnuelle C. Facioscapulohumeral muscular dystrophy.Biochim Biophys Acta. 2015 Apr;1852(4):607-14. doi: 10.1016/j.bbadis.2014.05.021.
  5. Tawil R, van der Maarel SM, Tapscott SJ. Facioscapulohumeral dystrophy: thepath to consensus on pathophysiology. Skelet Muscle. 2014 Jun 10;4:12. doi:10.1186/2044-5040-4-12.
  6. Yao Z, Snider L, Balog J, Lemmers RJ, Van Der Maarel SM, Tawil R, Tapscott SJ.DUX4-induced gene expression is the major molecular signature in FSHD skeletalmuscle. Hum Mol Genet. 2014 Oct 15;23(20):5342-52. doi: 10.1093/hmg/ddu251.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Vivi Li
View Times: 853
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 24 Dec 2020
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