Bare Lymphocyte Syndrome Type I

Version	Summary	Created by	Modification	Content Size	Created at	Operation
1		Catherine Yang	+ 577 word(s)	577	2020-12-15 07:17:11

Cite

If you have any further questions, please contact Encyclopedia Editorial Office.

Select a Style

Yang, C. Bare Lymphocyte Syndrome Type I. Encyclopedia. Available online: https://encyclopedia.pub/entry/4923 (accessed on 13 September 2026).

Yang C. Bare Lymphocyte Syndrome Type I. Encyclopedia. Available at: https://encyclopedia.pub/entry/4923. Accessed September 13, 2026.

Yang, Catherine. "Bare Lymphocyte Syndrome Type I" Encyclopedia, https://encyclopedia.pub/entry/4923 (accessed September 13, 2026).

Yang, C. (2020, December 24). Bare Lymphocyte Syndrome Type I. In Encyclopedia. https://encyclopedia.pub/entry/4923

Yang, Catherine. "Bare Lymphocyte Syndrome Type I." Encyclopedia. Web. 24 December, 2020.

Bare Lymphocyte Syndrome Type I

Edit

This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/bare-lymphocyte-syndrome-type-i

Bare lymphocyte syndrome type I (BLS I) is an inherited disorder of the immune system (primary immunodeficiency). Immunodeficiencies are conditions in which the immune system is not able to protect the body effectively from foreign invaders such as bacteria or viruses. Starting in childhood, most people with BLS I develop recurrent bacterial infections in the lungs and airways (respiratory tract). These recurrent infections can lead to a condition called bronchiectasis, which damages the passages leading from the windpipe to the lungs (bronchi) and can cause breathing problems.

genetic conditions

References

Eggensperger S, Tampé R. The transporter associated with antigen processing: akey player in adaptive immunity. Biol Chem. 2015 Sep;396(9-10):1059-72. doi:10.1515/hsz-2014-0320. Review.
Gadola SD, Moins-Teisserenc HT, Trowsdale J, Gross WL, Cerundolo V. TAPdeficiency syndrome. Clin Exp Immunol. 2000 Aug;121(2):173-8. Review.
Hanalioglu D, Ayvaz DC, Ozgur TT, van der Burg M, Sanal O, Tezcan I. A novelmutation in TAP1 gene leading to MHC class I deficiency: Report of two cases and review of the literature. Clin Immunol. 2017 May;178:74-78. doi:10.1016/j.clim.2017.01.011.
Parcej D, Tampé R. ABC proteins in antigen translocation and viral inhibition.Nat Chem Biol. 2010 Aug;6(8):572-80. doi: 10.1038/nchembio.410. Review. Erratumin: Nat Chem Biol. 2010 Oct;6(10):782.
Villa-Forte A, de la Salle H, Fricker D, Hentges F, Zimmer J. HLA class Ideficiency syndrome mimicking Wegener's granulomatosis. Arthritis Rheum. 2008Aug;58(8):2579-82. doi: 10.1002/art.23675.
Zimmer J, Andrès E, Donato L, Hanau D, Hentges F, de la Salle H. Clinical and immunological aspects of HLA class I deficiency. QJM. 2005 Oct;98(10):719-27.

©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.

Upload a video for this entry

Information

Subjects: Genetics & Heredity

Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Catherine Yang

View Times: 881

Entry Collection: MedlinePlus

Update Date: 24 Dec 2020

Table of Contents

Video Upload Options

References