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Yang, C. Autosomal Dominant Hyper-IgE Syndrome. Encyclopedia. Available online: https://encyclopedia.pub/entry/4891 (accessed on 27 September 2026).
Yang C. Autosomal Dominant Hyper-IgE Syndrome. Encyclopedia. Available at: https://encyclopedia.pub/entry/4891. Accessed September 27, 2026.
Yang, Catherine. "Autosomal Dominant Hyper-IgE Syndrome" Encyclopedia, https://encyclopedia.pub/entry/4891 (accessed September 27, 2026).
Yang, C. (2020, December 24). Autosomal Dominant Hyper-IgE Syndrome. In Encyclopedia. https://encyclopedia.pub/entry/4891
Yang, Catherine. "Autosomal Dominant Hyper-IgE Syndrome." Encyclopedia. Web. 24 December, 2020.
Autosomal Dominant Hyper-IgE Syndrome
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/autosomal-dominant-hyper-ige-syndrome

Autosomal dominant hyper-IgE syndrome (AD-HIES), formerly known as Job syndrome, is a condition that affects several body systems, particularly the immune system. Recurrent infections are common in people with this condition. Affected individuals tend to have frequent bouts of pneumonia, which are caused by certain kinds of bacteria that infect the lungs and cause inflammation. Inflammation is a normal immune system response to injury and foreign invaders (such as bacteria). However, excessive inflammation can damage body tissues. Recurring pneumonia often results in the formation of air-filled cysts (pneumatoceles) in the lungs. Frequent skin infections and an inflammatory skin disorder called eczema are also very common in AD-HIES. These skin problems cause rashes, blisters, accumulations of pus (abscesses), open sores, and scaling.

genetic conditions

References

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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Catherine Yang
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Update Date: 24 Dec 2020
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