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Xu, R. PDGFRB-Associated Chronic Eosinophilic Leukemia. Encyclopedia. Available online: https://encyclopedia.pub/entry/4863 (accessed on 29 September 2026).
Xu R. PDGFRB-Associated Chronic Eosinophilic Leukemia. Encyclopedia. Available at: https://encyclopedia.pub/entry/4863. Accessed September 29, 2026.
Xu, Rita. "PDGFRB-Associated Chronic Eosinophilic Leukemia" Encyclopedia, https://encyclopedia.pub/entry/4863 (accessed September 29, 2026).
Xu, R. (2020, December 24). PDGFRB-Associated Chronic Eosinophilic Leukemia. In Encyclopedia. https://encyclopedia.pub/entry/4863
Xu, Rita. "PDGFRB-Associated Chronic Eosinophilic Leukemia." Encyclopedia. Web. 24 December, 2020.
PDGFRB-Associated Chronic Eosinophilic Leukemia
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/pdgfrb-associated-chronic-eosinophilic-leukemia

PDGFRB-associated chronic eosinophilic leukemia is a type of cancer of blood-forming cells.

genetic conditions

References

  1. Apperley JF, Gardembas M, Melo JV, Russell-Jones R, Bain BJ, Baxter EJ, Chase A, Chessells JM, Colombat M, Dearden CE, Dimitrijevic S, Mahon FX, Marin D,Nikolova Z, Olavarria E, Silberman S, Schultheis B, Cross NC, Goldman JM.Response to imatinib mesylate in patients with chronic myeloproliferativediseases with rearrangements of the platelet-derived growth factor receptor beta.N Engl J Med. 2002 Aug 15;347(7):481-7.
  2. Arefi M, García JL, Peñarrubia MJ, Queizán JA, Hermosín L, López-Corral L,Megido M, Giraldo P, de las Heras N, Vanegas RJ, Gutiérrez NC, Hernández-RivasJM. Incidence and clinical characteristics of myeloproliferative neoplasmsdisplaying a PDGFRB rearrangement. Eur J Haematol. 2012 Jul;89(1):37-41. doi:10.1111/j.1600-0609.2012.01799.x.
  3. Chang H, Chuang WY, Sun CF, Barnard MR. Concurrent acute myeloid leukemia and T lymphoblastic lymphoma in a patient with rearranged PDGFRB genes. Diagn Pathol.2012 Feb 22;7:19. doi: 10.1186/1746-1596-7-19.
  4. Cross NC, Reiter A. Fibroblast growth factor receptor and platelet-derivedgrowth factor receptor abnormalities in eosinophilic myeloproliferativedisorders. Acta Haematol. 2008;119(4):199-206. doi: 10.1159/000140631.
  5. Galimberti S, Ferreri MI, Simi P, Azzarà A, Baratè C, Fazzi R, Cecconi N,Cervetti G, Guerrini F, Petrini M. Platelet-derived growth factor beta receptor(PDGFRB) gene is rearranged in a significant percentage of myelodysplasticsyndromes with normal karyotype. Br J Haematol. 2009 Dec;147(5):763-6. doi:10.1111/j.1365-2141.2009.07878.x.
  6. Gotlib J. Eosinophilic myeloid disorders: new classification and noveltherapeutic strategies. Curr Opin Hematol. 2010 Mar;17(2):117-24. doi:10.1097/MOH.0b013e3283366c70. Review.
  7. Gotlib J. World Health Organization-defined eosinophilic disorders: 2012update on diagnosis, risk stratification, and management. Am J Hematol. 2012Sep;87(9):903-14. doi: 10.1002/ajh.23293.
  8. Haferlach C, Bacher U, Schnittger S, Alpermann T, Zenger M, Kern W, Haferlach T. ETV6 rearrangements are recurrent in myeloid malignancies and are frequentlyassociated with other genetic events. Genes Chromosomes Cancer. 2012Apr;51(4):328-37. doi: 10.1002/gcc.21918.
  9. Noel P. Eosinophilic myeloid disorders. Semin Hematol. 2012 Apr;49(2):120-7.doi: 10.1053/j.seminhematol.2012.01.008. Review.
  10. Zhou MH, Gao L, Jing Y, Xu YY, Ding Y, Wang N, Wang W, Li MY, Han XP, Sun JZ, Wang LL, Yu L. Detection of ETV6 gene rearrangements in adult acute lymphoblasticleukemia. Ann Hematol. 2012 Aug;91(8):1235-43. doi: 10.1007/s00277-012-1431-4.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Rita Xu
View Times: 634
Entry Collection: MedlinePlus
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Update Date: 24 Dec 2020
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