apolipoprotein A1. The APOA1 gene provides instructions for making a protein called apolipoprotein A-I (apoA-I).
genes
References
Batal R, Tremblay M, Krimbou L, Mamer O, Davignon J, Genest J Jr, Cohn JS.Familial HDL deficiency characterized by hypercatabolism of mature apoA-I but notproapoA-I. Arterioscler Thromb Vasc Biol. 1998 Apr;18(4):655-64.
Chambenoit O, Hamon Y, Marguet D, Rigneault H, Rosseneu M, Chimini G. Specificdocking of apolipoprotein A-I at the cell surface requires a functional ABCA1transporter. J Biol Chem. 2001 Mar 30;276(13):9955-60.
Chroni A, Liu T, Gorshkova I, Kan HY, Uehara Y, Von Eckardstein A, Zannis VI. The central helices of ApoA-I can promote ATP-binding cassette transporter A1(ABCA1)-mediated lipid efflux. Amino acid residues 220-231 of the wild-typeApoA-I are required for lipid efflux in vitro and high density lipoproteinformation in vivo. J Biol Chem. 2003 Feb 28;278(9):6719-30.
Daum U, Leren TP, Langer C, Chirazi A, Cullen P, Pritchard PH, Assmann G, von Eckardstein A. Multiple dysfunctions of two apolipoprotein A-I variants,apoA-I(R160L)Oslo and apoA-I(P165R), that are associated withhypoalphalipoproteinemia in heterozygous carriers. J Lipid Res. 1999Mar;40(3):486-94.
Eriksson M, Schönland S, Yumlu S, Hegenbart U, von Hutten H, Gioeva Z, LohseP, Büttner J, Schmidt H, Röcken C. Hereditary apolipoprotein AI-associatedamyloidosis in surgical pathology specimens: identification of three novelmutations in the APOA1 gene. J Mol Diagn. 2009 May;11(3):257-62. doi:10.2353/jmoldx.2009.080161.
Oram JF. HDL apolipoproteins and ABCA1: partners in the removal of excesscellular cholesterol. Arterioscler Thromb Vasc Biol. 2003 May 1;23(5):720-7.
Rowczenio D, Dogan A, Theis JD, Vrana JA, Lachmann HJ, Wechalekar AD,Gilbertson JA, Hunt T, Gibbs SD, Sattianayagam PT, Pinney JH, Hawkins PN,Gillmore JD. Amyloidogenicity and clinical phenotype associated with five novelmutations in apolipoprotein A-I. Am J Pathol. 2011 Oct;179(4):1978-87. doi:10.1016/j.ajpath.2011.06.024.
You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
OK
Confirm
Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?