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Tang, P. ZIC2 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4657 (accessed on 29 September 2026).
Tang P. ZIC2 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4657. Accessed September 29, 2026.
Tang, Peter. "ZIC2 Gene" Encyclopedia, https://encyclopedia.pub/entry/4657 (accessed September 29, 2026).
Tang, P. (2020, December 24). ZIC2 Gene. In Encyclopedia. https://encyclopedia.pub/entry/4657
Tang, Peter. "ZIC2 Gene." Encyclopedia. Web. 24 December, 2020.
ZIC2 Gene
Edit

Zic family member 2

genes

References

  1. Brown LY, Odent S, David V, Blayau M, Dubourg C, Apacik C, Delgado MA, HallBD, Reynolds JF, Sommer A, Wieczorek D, Brown SA, Muenke M. Holoprosencephaly dueto mutations in ZIC2: alanine tract expansion mutations may be caused by parentalsomatic recombination. Hum Mol Genet. 2001 Apr 1;10(8):791-6.
  2. Brown SA, Warburton D, Brown LY, Yu CY, Roeder ER, Stengel-Rutkowski S,Hennekam RC, Muenke M. Holoprosencephaly due to mutations in ZIC2, a homologue ofDrosophila odd-paired. Nat Genet. 1998 Oct;20(2):180-3.
  3. Dubourg C, Bendavid C, Pasquier L, Henry C, Odent S, David V.Holoprosencephaly. Orphanet J Rare Dis. 2007 Feb 2;2:8. Review.
  4. Roessler E, Lacbawan F, Dubourg C, Paulussen A, Herbergs J, Hehr U, BendavidC, Zhou N, Ouspenskaia M, Bale S, Odent S, David V, Muenke M. The full spectrumof holoprosencephaly-associated mutations within the ZIC2 gene in humans predictsloss-of-function as the predominant disease mechanism. Hum Mutat. 2009Apr;30(4):E541-54. doi: 10.1002/humu.20982.
  5. Roessler E, Muenke M. The molecular genetics of holoprosencephaly. Am J MedGenet C Semin Med Genet. 2010 Feb 15;154C(1):52-61. doi: 10.1002/ajmg.c.30236.Review.
  6. Solomon BD, Lacbawan F, Mercier S, Clegg NJ, Delgado MR, Rosenbaum K, Dubourg C, David V, Olney AH, Wehner LE, Hehr U, Bale S, Paulussen A, Smeets HJ, HardistyE, Tylki-Szymanska A, Pronicka E, Clemens M, McPherson E, Hennekam RC, Hahn J,Stashinko E, Levey E, Wieczorek D, Roeder E, Schell-Apacik CC, Booth CW, ThomasRL, Kenwrick S, Cummings DA, Bous SM, Keaton A, Balog JZ, Hadley D, Zhou N, Long R, Vélez JI, Pineda-Alvarez DE, Odent S, Roessler E, Muenke M. Mutations in ZIC2 in human holoprosencephaly: description of a novel ZIC2 specific phenotype andcomprehensive analysis of 157 individuals. J Med Genet. 2010 Aug;47(8):513-24.doi: 10.1136/jmg.2009.073049.
  7. Solomon BD, Mercier S, Vélez JI, Pineda-Alvarez DE, Wyllie A, Zhou N, Dubourg C, David V, Odent S, Roessler E, Muenke M. Analysis of genotype-phenotypecorrelations in human holoprosencephaly. Am J Med Genet C Semin Med Genet. 2010Feb 15;154C(1):133-41. doi: 10.1002/ajmg.c.30240. Review.
  8. Tekendo-Ngongang C, Muenke M, Kruszka P. Holoprosencephaly Overview. 2000 Dec 27 [updated 2020 Mar 5]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, BeanLJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA):University of Washington, Seattle; 1993-2020. Available fromhttp://www.ncbi.nlm.nih.gov/books/NBK1530/
  9. Warr N, Powles-Glover N, Chappell A, Robson J, Norris D, Arkell RM.Zic2-associated holoprosencephaly is caused by a transient defect in theorganizer region during gastrulation. Hum Mol Genet. 2008 Oct 1;17(19):2986-96.doi: 10.1093/hmg/ddn197.
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