Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Catherine Yang + 538 word(s) 538 2020-12-15 07:14:55

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
No, upload directly Yes
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Yang, C. Adenosine Deaminase Deficiency. Encyclopedia. Available online: https://encyclopedia.pub/entry/4652 (accessed on 26 September 2026).
Yang C. Adenosine Deaminase Deficiency. Encyclopedia. Available at: https://encyclopedia.pub/entry/4652. Accessed September 26, 2026.
Yang, Catherine. "Adenosine Deaminase Deficiency" Encyclopedia, https://encyclopedia.pub/entry/4652 (accessed September 26, 2026).
Yang, C. (2020, December 24). Adenosine Deaminase Deficiency. In Encyclopedia. https://encyclopedia.pub/entry/4652
Yang, Catherine. "Adenosine Deaminase Deficiency." Encyclopedia. Web. 24 December, 2020.
Adenosine Deaminase Deficiency
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/adenosine-deaminase-deficiency

Adenosine deaminase (ADA) deficiency is an inherited disorder that damages the immune system and causes severe combined immunodeficiency (SCID). People with SCID lack virtually all immune protection from bacteria, viruses, and fungi. They are prone to repeated and persistent infections that can be very serious or life-threatening. These infections are often caused by "opportunistic" organisms that ordinarily do not cause illness in people with a normal immune system.

genetic conditions

References

  1. Blackburn MR, Thompson LF. Adenosine deaminase deficiency: unanticipatedbenefits from the study of a rare immunodeficiency. J Immunol. 2012 Feb1;188(3):933-5. doi: 10.4049/jimmunol.1103519.
  2. Buckley RH. Molecular defects in human severe combined immunodeficiency andapproaches to immune reconstitution. Annu Rev Immunol. 2004;22:625-55. Review.
  3. Hershfield MS. Genotype is an important determinant of phenotype in adenosine deaminase deficiency. Curr Opin Immunol. 2003 Oct;15(5):571-7. Review.
  4. Hershfield MS. New insights into adenosine-receptor-mediated immunosuppressionand the role of adenosine in causing the immunodeficiency associated withadenosine deaminase deficiency. Eur J Immunol. 2005 Jan;35(1):25-30. Review.
  5. Nofech-Mozes Y, Blaser SI, Kobayashi J, Grunebaum E, Roifman CM. Neurologicabnormalities in patients with adenosine deaminase deficiency. Pediatr Neurol.2007 Sep;37(3):218-21.
  6. Nyhan WL. Disorders of purine and pyrimidine metabolism. Mol Genet Metab. 2005Sep-Oct;86(1-2):25-33. Review.
More
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.
Upload a video for this entry
Information
Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Catherine Yang
View Times: 1.0K
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 24 Dec 2020
Table of Contents
    Notice
    You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
    OK
    Confirm
    Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
    Yes
    No
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    There is no comment~
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    ${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
    Submit
    Cancel
    Confirm
    Are you sure to Delete?
    Yes No
    Academic Video Service
    Feedback