WNT5A Gene

Version	Summary	Created by	Modification	Content Size	Created at	Operation
1		Peter Tang	+ 274 word(s)	274	2020-12-15 08:14:37

Cite

If you have any further questions, please contact Encyclopedia Editorial Office.

Select a Style

Tang, P. WNT5A Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4600 (accessed on 29 September 2026).

Tang P. WNT5A Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4600. Accessed September 29, 2026.

Tang, Peter. "WNT5A Gene" Encyclopedia, https://encyclopedia.pub/entry/4600 (accessed September 29, 2026).

Tang, P. (2020, December 24). WNT5A Gene. In Encyclopedia. https://encyclopedia.pub/entry/4600

Tang, Peter. "WNT5A Gene." Encyclopedia. Web. 24 December, 2020.

WNT5A Gene

Edit

This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/wnt5a

Wnt family member 5A: The WNT5A gene is part of a large family of WNT genes, which play critical roles in development starting before birth. These genes provide instructions for making proteins that participate in chemical signaling pathways in the body.

genes

References

Kikuchi A, Yamamoto H, Sato A, Matsumoto S. Wnt5a: its signalling, functionsand implication in diseases. Acta Physiol (Oxf). 2012 Jan;204(1):17-33. doi:10.1111/j.1748-1716.2011.02294.x.
Mikels AJ, Nusse R. Purified Wnt5a protein activates or inhibitsbeta-catenin-TCF signaling depending on receptor context. PLoS Biol. 2006Apr;4(4):e115.
Nishita M, Enomoto M, Yamagata K, Minami Y. Cell/tissue-tropic functions ofWnt5a signaling in normal and cancer cells. Trends Cell Biol. 2010Jun;20(6):346-54. doi: 10.1016/j.tcb.2010.03.001.
Person AD, Beiraghi S, Sieben CM, Hermanson S, Neumann AN, Robu ME,Schleiffarth JR, Billington CJ Jr, van Bokhoven H, Hoogeboom JM, Mazzeu JF,Petryk A, Schimmenti LA, Brunner HG, Ekker SC, Lohr JL. WNT5A mutations inpatients with autosomal dominant Robinow syndrome. Dev Dyn. 2010Jan;239(1):327-37. doi: 10.1002/dvdy.22156.
Roifman M, Marcelis CL, Paton T, Marshall C, Silver R, Lohr JL, Yntema HG,Venselaar H, Kayserili H, van Bon B, Seaward G; FORGE Canada Consortium, Brunner HG, Chitayat D. De novo WNT5A-associated autosomal dominant Robinow syndromesuggests specificity of genotype and phenotype. Clin Genet. 2015;87(1):34-41.doi: 10.1111/cge.12401.
White JJ, Mazzeu JF, Coban-Akdemir Z, Bayram Y, Bahrambeigi V, Hoischen A, vanBon BWM, Gezdirici A, Gulec EY, Ramond F, Touraine R, Thevenon J, Shinawi M,Beaver E, Heeley J, Hoover-Fong J, Durmaz CD, Karabulut HG, Marzioglu-Ozdemir E, Cayir A, Duz MB, Seven M, Price S, Ferreira BM, Vianna-Morgante AM, Ellard S,Parrish A, Stals K, Flores-Daboub J, Jhangiani SN, Gibbs RA; Baylor-HopkinsCenter for Mendelian Genomics, Brunner HG, Sutton VR, Lupski JR, Carvalho CMB.WNT Signaling Perturbations Underlie the Genetic Heterogeneity of RobinowSyndrome. Am J Hum Genet. 2018 Jan 4;102(1):27-43. doi:10.1016/j.ajhg.2017.10.002.

©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.

Upload a video for this entry

Information

Subjects: Genetics & Heredity

Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Peter Tang

View Times: 734

Entry Collection: MedlinePlus

Update Date: 24 Dec 2020

Table of Contents

Video Upload Options

References