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Mamun, A.; Sabantina, L. Electrospun Magnetic Nanofiber Mats in Cancer Treatment Applications. Encyclopedia. Available online: (accessed on 14 June 2024).
Mamun A, Sabantina L. Electrospun Magnetic Nanofiber Mats in Cancer Treatment Applications. Encyclopedia. Available at: Accessed June 14, 2024.
Mamun, Al, Lilia Sabantina. "Electrospun Magnetic Nanofiber Mats in Cancer Treatment Applications" Encyclopedia, (accessed June 14, 2024).
Mamun, A., & Sabantina, L. (2023, June 20). Electrospun Magnetic Nanofiber Mats in Cancer Treatment Applications. In Encyclopedia.
Mamun, Al and Lilia Sabantina. "Electrospun Magnetic Nanofiber Mats in Cancer Treatment Applications." Encyclopedia. Web. 20 June, 2023.
Electrospun Magnetic Nanofiber Mats in Cancer Treatment Applications

The number of cancer patients is rapidly increasing worldwide. Among the leading causes of human death, cancer can be regarded as one of the major threats to humans. Although many new cancer treatment procedures such as chemotherapy, radiotherapy, and surgical methods are being developed and used for testing purposes, results show limited efficiency and high toxicity, even if they have the potential to damage cancer cells in the process. In contrast, magnetic hyperthermia is a field that originated from the use of magnetic nanomaterials, which, due to their magnetic properties and other characteristics, are used in many clinical trials as one of the solutions for cancer treatment. Magnetic nanomaterials can increase the temperature of nanoparticles located in tumor tissue by applying an alternating magnetic field. 

magnetic hyperthermia electrospun magnetic nanofiber mats magnetic nanomaterials targeted drug delivery cancer treatment magnetic nanofibers

1. Introduction

According to statistical data from the International Agency for Research on Cancer, the number of cancer deaths worldwide in 2020 was estimated at around 9.96 million, and new cancer cases were estimated at around 19.3 million [1]. The number of global cancer cases is projected to increase to 28.4 million by 2040, representing an increase of nearly 50% in the next 20 years [2], making the disease a great threat to human beings worldwide [3][4]. However, various treatment modalities such as hyperthermia, radiotherapy, chemotherapy, photodynamic therapy, hormone therapy, immunotherapy, stem cell transplantation, surgery, biomarker testing, etc., are currently being developed and tested to address this global issue [5][6][7][8]. Among these, chemotherapy, radiotherapy, and hyperthermia have proved to be successful treatment methods that can kill cancer cells [8][9][10]. Nevertheless, toxicity and side effects are very high in chemotherapy and radiotherapy methods [11][12]. For this reason, hyperthermia is the most attractive and effective recent treatment method that does not have toxicity to healthy tissues [13][14][15]. Specific hyperthermia therapy comprises three treatment modalities: whole-body hyperthermia, regional hyperthermia, and local hyperthermia. If cancer cells are detected in the initial stage, local hyperthermia is applied; if the affected area is larger than the tumor, regional hyperthermia is applied to a complete tissue or organ; if cancer is detected in the final stage, the affected cells are distributed throughout the body, and whole-body hyperthermia should be applied [16]. In the final case, the treatment process can be more complicated and harmful and can sometimes damage healthy tissue [17][18][19]. Therefore, it is very important to detect tumor cells in their early stages. During hyperthermia treatment, heat is generated in the tumor area to kill the affected cells by introducing external substances into the tumor [20]. Affected cancer cells die as soon as the temperature exceeds 42 °C because cancer cells are more sensitive than healthy cells [21][22][23]. Healthy cells, in contrast, can survive at this temperature [24]. Several methods for energy transfer with external devices are used to generate temperature in the target tissue [25]. For this process, laser, ultrasound, induction heating, electromagnetic waves, radio frequency, microwaves, infrared radiation, etc., are usually used to generate heat [26][27][28]. However, the traditional hyperthermia procedure has some limitations and challenges due to insufficient penetration of heat waves into tissues when using lasers, ultrasound, and microwaves, overheating of healthy cells, and severe side effects occurring as a result of combustion. Recently, medical scientists, in collaboration with materials scientists, have developed magnetic nanostructures to generate heat for this purpose using magnetic nanomaterials, especially iron oxide nanoparticles with superparamagnetic behavior, as these materials can generate heat under an alternating magnetic field [29][30][31]. In addition, magnetic hyperthermia is more effective and less harmful to healthy cells, and it can also help overcome the limitations of the traditional hyperthermia process. In contrast, therapeutic and diagnostic materials, such as theranostic devices, have recently become a very interesting research area in the medical field to enable faster and more effective cancer treatment, imaging, and diagnosis [32][33][34]. Figure 1 shows a graphical abstract of the production of electrospun magnetic nanofiber mats, which can also be conditionally loaded with drugs for use in therapeutic and diagnostic procedures for cancer treatment.
Figure 1. Graphical abstract showing the use of electrospun magnetic nanofiber mats in therapeutic and diagnostic methods for cancer treatment.
Moreover, the most suitable and recently developed materials, especially magnetic nanomaterials, are used for these purposes [35]. Electrospun nanofiber mats with magnetic additives are promising materials for biomedical applications [36][37] such as targeted drug release in tumors and theranostic devices for cancer treatment. They have great potential in this field due to the unique physical and chemical properties of electrospun nanofibers, including their networks of nanoporous and microporous structures, their large specific surface-to-volume ratio, tunable porosity, and flexible surface functionality [38][39][40][41][42][43]. Electrospinning is a very simple, cost-effective, and environmentally friendly process for producing nanofibers from various polymers [44] and even ceramics [45]. In addition, electrospun magnetic nanofiber mats can be produced from bio- or natural polymer solutions with magnetic additives [46].

2. Fabrication Technique for Electrospun Magnetic Nanofiber Mats

Nanofiber and electrospun nanofiber mat fabrication technology is an interesting research area for scientists. Various methods for fabricating nanofiber mats have been described in the literature, such as melt electrospinning, self-bundling, multi-nozzle electrospinning, bubble electrospinning, electro-blowing, cylindrical porous hollow tube electrospinning, and electrospinning. Electrospinning is a very simple, easy, environmentally friendly, inexpensive, and popular method for fabricating nanofibers [47][48]. It can be used to produce very fine fibers or fiber mats with diameters in the nanometer range for both academic and industrial research purposes. Depending on their application, electrospun nanofiber mats can be made from a variety of materials, such as natural or biopolymers, polymer composites or melts, inorganic or inorganic–organic materials, metallic nanoparticles, particulates, carbon nanotubes, and even ceramics [49][50][51].
In general, there are two types of electrospinning processes: needle-based electrospinning and needle-free electrospinning.

3. Magnetic Hyperthermia Process and Materials

3.1. Hyperthermia

Hyperthermia is a procedure used in medical science to treat cancer by heating cancer cells, and thus killing them, using various techniques. Depending on the targeted cancer cells, temperatures range from 39 °C to 46 °C [52][53][54][55][56][57][58]. Some essential components to increase the temperature of tumor cells include ultrasound, radiofrequency (in the range from 100 kHz to 150 MHz), microwaves (wavelengths from 433 to 2450 MHz), hot water perfusion (pipes, ceilings), infrared emitters, nanoparticles, magnetic iron oxide nanoparticles, and resistive wire implants in a hyperthermia system [59][60][61][62][63][64][65][66][67][68].

3.2. Magnetic Hyperthermia

Research has found that magnetic hyperthermia is a novel procedure that offers a safe, powerful, and simple treatment method to meet these complicated challenges [69][70][71][72][73]. In this procedure, which has recently seen rapid development, magnetic nanomaterials can be used to improve hyperthermia efficiency compared to traditional hyperthermia methods for the erosion of tumors [74][75][76][77][78][79][80][81][82][83]. The most significant aspect of magnetic hyperthermia is that magnetic nanomaterials are distributed over very small areas so that the temperature behavior of healthy cells is not affected [84][85][86]. For this purpose, the highest possible saturation magnetization can be achieved with multifunctional iron oxide-based magnetic nanomaterials used on the specific therapeutic side of cancer cells. These magnetic nanomaterials are capable of generating thermal energy when an external magnetic field is applied. In magnetic hyperthermia, two types of external fields are applied: dynamic/oscillating and static [87][88][89][90][91][92][93]. In an oscillating field, an alternating current source is connected to the field, which fluctuates with frequency. It is referred to as an alternating magnetic field. Therefore, two different methods—switching the external magnetic field and changing the direction of the magnetic field—can be used to release this alternative magnetic field for magnetic hyperthermia [94]. Moreover, these low-frequency alternating magnetic fields (100 kHz–1 MHz) can deeply penetrate the body without causing significant attenuation losses [95][96][97][98]. Alternating magnetic fields with amplitudes of tens of kA/m and frequencies of 100 kHz and 1 MHz are applied in the target area so that the magnetic energy of the magnetic nanomaterials is directed toward the applied magnetic field [99][100][101][102][103]. The magnetic energy is transformed into thermal energy under different conditions, which can increase the temperature of cancerous tissue and consequently cause apoptosis or necrosis in the tumor [104][105][106][107][108]. It is known that iron-based magnetic nanomaterials can destroy the affected cells without being toxic, and the aggregated nanomaterials are excreted from the body after several weeks [109][110][111][112][113]. The main mechanisms of heat generation under an alternative magnetic field based on the properties of magnetic nanomaterials are as follows: i. hysteresis power loss of the magnetic nanoparticles, ii. Néel relaxation, and iii. frictional losses due to Brownian rotation in the magnetic particles. Applied gradually, these mechanisms lead to a saturation of thermal energy [114][115][116][117][118][119][120].

3.3. Magnetic Hyperthermia Involving Magnetic Nanomaterials

Due to the magnetic and superparamagnetic properties of nanomagnetic materials, they are becoming increasingly attractive nano-devices for medical science aiming to improve diagnostic precision and the treatment of diseases, especially cancer [121][122][123][124][125][126][127][128][129][130][131][132][133][134]. The main sources of magnetic nanoparticles are pure metals, their oxides, or metal alloys. Therefore, due to the high magnetization and oxidation properties of pure metal, as well as their high toxicity, metal oxide nanomaterials (such as magnetite, maghemite, and other ferrites, including Co, Mn, Ni, Zn, and others) are preferable for biomedical applications [135][136][137][138]. Their superparamagnetic properties, biocompatibility, and chemical stability are excellent characteristics for this purpose. In addition, magnetic nanomaterials respond to the alternative magnetic field by generating thermal energy, which is effective in magnetic hyperthermia. With a specific nanometer size of less than 20 nm, Fe3O4 is the most attractive magnetic nanomaterial due to its properties, which include superparamagnetic, high saturation magnetization, soft magnetic behavior, suitable particle shape and size, easy synthesis, and low density [139][140]. In addition, thermal efficiency depends on the main function of intermolecular interactions, dipolar interaction between particles, particle size and geometry, saturation magnetization, relaxation time (Néel and Brown), magnetic anisotropy, and superparamagnetic properties [141][142][143]. The generated heat is mainly due to the energy lost in overcoming the rotational energy barrier of the alternating magnetic field for a superparamagnetic nanomaterial smaller than the single-domain region.
Consequently, such magnetic nanomaterials, possibly combined with polymeric materials, can be used in cancer treatment as a therapeutic device platform for drug release, as imaging probes for cancer diagnostics, and for magnetic hyperthermia [144][145][146][147][148].

3.4. Mechanism of Thermal Energy Generation Using Magnetic Nanomaterials

Normally, magnetic hysteresis losses are observed in magnetic nanomaterials when an external magnetic field is applied [149][150]. These magnetic losses largely depend on the magnetic features of the magnetic nanomaterials based on their size [151]. For example, a multi-domain state is evident in bulk materials. However, the thermal energy generated using both single- and multi-domain magnetic nanomaterials is always a function of hysteresis losses, which depends on how fast the magnetization follows the alternating magnetic field (AMF) changes [152][153][154][155][156][157]. Moreover, the amount of magnetic energy transformed into heat during magnetization reversal follows the magnetic loss in the magnetic nanoparticles. Thus, the thermal energy generated using the magnetic nanomaterial is approximately equal to the area of the hysteresis loop formed during one cycle of the magnetic field [158][159][160].
In addition, movement is required to overcome the friction between the magnetization easy axis and the atomic lattices for the Néel relaxation or between magnetic nanomaterials and their surroundings for Brownian relaxation, leading to the loss of electromagnetic energy and the production of thermal energy [161][162][163].

3.5. Magnetic Hyperthermia with Electrospun Magnetic Nanofiber Mats

The potential biomedical applications of magnetic nanostructures can be enhanced by adding magnetic nanomaterials to composite polymers [164][165]. The large surface area of the nanomaterials, the irregular composition, and the shape of the magnetic nanomaterials lead to an imbalance in dipolar attraction and a strong interaction between the particles [166][167]. The temperature, concentration of nanomaterials, surface charge of nanoparticles, dielectric constant, ionic strength of the medium, presence of surfactants, magnetic attraction force, high surface energy, and van der Waals forces are the basic parameters that lead to the agglomeration of magnetic nanomaterials to the polymer matrix [168][169]. Magnetic particles generate heat when exposed to an external alternating magnetic field by various physical mechanisms such as relaxation loss or hysteresis loss [170][171][172]. All hysteresis losses occur in the hysteresis loop area of superparamagnetic or ferromagnetic/ferrimagnetic nanomaterials [173][174][175][176][177]. As the magnetic nanomaterials are fixed inside the electrospun magnetic nanofiber mats, they generally cannot rotate freely in the applied magnetic field. Typically, magnetic materials can experience heating through any of the four distinct mechanisms when subjected to high-frequency magnetic fields, namely eddy currents and hysteresis loss, as well as Brownian and Néel relaxation [178][179][180]. Zhong et al. have shown, for example, that for fixed magnetic nanomaterials in the polymer matrix, magnetic reversal losses are responsible for heat generation. Since the magnetic nanomaterials are incorporated into the fiber mats and thus fixed, the complete rotation of the nanomaterials (extrinsic relaxation) can be avoided. From the hysteresis curve of the nanomaterials, a coercivity of about 80 Oe and a relative remanence of 0.12 were determined. These values are a clear indication of a dominant ferrimagnetic behavior of the nanomaterials in the fibers, so hysteresis will be the main loss mechanism in magnetization reversal. Due to the size distribution of the magnetic nanomaterials, there will also be a fraction of very small superparamagnetic nanomaterials within the particle ensemble. Their magnetization will be reversed via Néel relaxation [181].
The magnetization dynamics of low-dimensional objects consist of many factors, e.g., the geometric shape, which determines the prevailing competition between demagnetization and exchange energy, as shown in the study by Steblinski et al. [182]. Using electrospinning techniques, magnetic nanoparticles can be embedded into electrospun nanofibers and other polymeric matrices to create defined magnetic and mechanical properties. The metal oxide nanoparticles have a strong tendency to form agglomerations—an effect that, as a consequence, changes the magnetic properties of the composites. The study by Blachowicz et al. investigated metal oxide nanoparticles such as magnetite or nickel ferrite and their embedding into a polymer to avoid oxidation. It also investigated the influence of agglomeration on the magnetic properties of metal oxide nanoparticles with different diameters in non-magnetic matrices [183].

4. Drug Delivery and Electrospun Magnetic Nanofiber Mats for Cancer Treatment

The controlled release of targeted drugs is one of the most important research areas in cancer treatment, as it is one of the major challenges in medical science. Electrospinning opens new possibilities to load nanofiber mats with drugs, including thermolabile drugs, and release them in a controlled way. The excellent properties of nanofiber mats, e.g., their good mechanical stability, controlled loading and release of a variety of drugs, low toxicity, and the possibility of encapsulation, play a major role in therapy [184].
However, magnetic nanomaterial-based drugs can also be applied in cancer treatment using electrospun magnetic nanofiber mats under an alternative magnetic field due to the magnetic response of electrospun magnetic nanofiber mats and some physical and chemical properties [185][186][187][188]. This function is based on some important parameters, including the ratio of polymer to magnetic nanomaterials, the concentration of magnetic nanomaterials, and the distribution of size and magnetic nanomaterials within the electrospun magnetic nanofiber mats [189]. Due to the porous structure of electrospun magnetic nanofiber mats, the original mechanism of drug delivery is diffusion. When an external magnetic field is applied to the electrospun nanofiber mats, the magnetic nanomaterials try to align and form a barrier within the nanostructure. Small drug molecules then come out of the porous structure because the magnetic barriers limit the capacity of drug molecules with a very low diffusion rate. When the external magnetic field is removed and the alignment of the magnetic nanomaterials is damaged, the small drug molecules in the target tissue are released again. Electrospun magnetic nanofiber mats can thus also be used as a drug trigger for tumor cells when needed for cancer treatment [190][191][192][193][194][195][196][197].
The study of Miyako and Yu deals with the alternating magnetic field-mediated wireless manipulations of liquid metal for use in therapeutic bioengineering. Therapeutic bioengineering applications of liquid metals (LMs) in vitro and in vivo demonstrated efficacy in magnetic cancer hyperthermia using a wireless alternating magnetic field (AMF) as well as remote manipulation of a pill-shaped microdevice based on an LM/hydrogel composite. In addition, AMFs were used effectively to eradicate tumors in vitro and in vivo with EGaIn by means of heat dissipation via eddy currents.
Bazzazzadeh et al. prepared poly(acrylic acid)-grafted chitosan/polyurethane/magnetic MIL-53 nanofibers with a metal–organic core–sheath for simultaneous administration of temozolomide and paclitaxel against glioblastoma cancer cells and for heat generation under an alternating magnetic field for mild hyperthermia of cells treated with magnetic MIL-53 fibers containing 5 wt% grafted-chitosan(GS)-g-poly(acrylic acid) (PAA)-paclitaxel (PTX)-temozolomide (TMZ)/polyurethane (PU) for 10 min. The study results suggest that the electrospun magnetic core–shell nanofiber mats could be used for the targeted delivery of anticancer drugs and magnetic hyperthermia applications in cancer treatment [198].

5. Diagnostics Technology and Electrospun Magnetic Nanofiber Mats and Magnetic Nanomaterials for Cancer Treatment

The detection technique with which cancer is diagnosed plays an important role in cancer treatment. There are various kinds of detection processes in medical imaging tools and techniques including photography, microscopy, ultrasound, X-rays, computed tomography (CT) scans, magnetic particle imaging (MPI), magnetic resonance imaging (MRI), positron emission tomography (PET), etc. All of them, especially MRI and MPI, are very important tools for cancer treatment. On the one hand, MRI is very promising due to the deep penetration ability and high spatial resolution achieved using contrast agents. However, the sensitivity of T1-weighted MRI agents is low, and in T2-weighted MRI, the agents are challenging to detect in biological tissues. For this reason, magnetic nanomaterials are considered more promising T2 MRI contrast agents, and iron-based magnetic nanomaterials in particular have a longer half-life than clinically used gadolinium-based contrast agents [199][200][201][202][203]. Electrospun magnetic nanofiber mats can be loaded with a precise number of magnetic nanoparticles and implanted directly into the tumor site to enhance diagnostics. Additionally, these nanofiber mats can be used to amplify biosensor signals and improve the accuracy and sensitivity of bioassays. They are also suitable for the isolation and detection of circulating tumor cells, which is a crucial diagnostic tool. Thus, electrospun magnetic nanofiber mats are an ideal material for various diagnostic applications [204].
For example, Illés et al. used superparamagnetic nanoparticles to develop image contrast for MRI diagnosis and showed the highest values of r2 relaxivity (451 mM−1s−1) for MRI tools [205]. In addition, Khizar et al. applied magnetic cobalt ferrite nanoparticles for the combined application of MRI and magnetic hyperthermia [206]. Moreover, Islam et al. used Mn Fe2O4 nanoparticles in MRI and hyperthermia studies [207]. Nevertheless, MPI, in which magnetic nanoparticles are used, has been widely used in cancer treatment in recent times. However, the localization and concentration of magnetic nanoparticles could provide real-time 3D imaging information and can be applied in multiple medical imaging applications. Currently, electrospun magnetic nanofiber mats are also being developed for detecting tumor cells using MPI [208][209][210]. For example, Yu et al. used superparamagnetic iron oxide to study the magnetic particle imaging (MPI) tracer imaging modality and showed that the superparamagnetic iron oxide nanoparticle tracer exhibited high image contrast [207]. However, functionalized electrospun magnetic nanofiber mats and nanomaterials are new development materials for magnetic hyperthermia, which are simultaneously proving to be imaging diagnostic materials in the field of medicine [211][212][213][214][215].


  1. International Agency for Research on Cancer, WHO. Breast Cancer, Latest Global Cancer Data: Cancer Burden Rises to 19.3 Million New Cases and 10.0 Million Cancer Deaths in 2020. 2020. Available online: (accessed on 20 March 2023).
  2. Sung, H.; Ferlay, J.; Siegel, R.L.; Laversanne, M.; Soerjomataram, I.; Jemal, A.; Bray, F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. Cancer J. Clin. 2021, 71, 209–249.
  3. Brero, F.; Albino, M.; Antoccia, A.; Arosio, P.; Avolio, M.; Berardinelli, F.; Bettega, D.; Calzolari, P.; Ciocca, M.; Corti, M.; et al. Hadron Therapy, Magnetic Nanoparticles and Hyperthermia: A Promising Combined Tool for Pancreatic Cancer Treatment. Nanomaterials 2020, 10, 1919.
  4. Osial, M.; Pregowska, A. The Application of Artificial Intelligence in Magnetic Hyperthermia Based Research. Future Internet 2022, 14, 356.
  5. Nishikawa, A.; Suzuki, Y.; Kaneko, M.; Ito, A. Combination of magnetic hyperthermia and immunomodulators to drive complete tumor regression of poorly immunogenic melanoma. Cancer Immunol. Immunother. 2022, 1–12.
  6. Stone, R.; Willi, T.; Rosen, Y.; Mefford, O.; Alexis, F. Targeted magnetic hyperthermia. Ther. Deliv. 2011, 2, 815–838.
  7. Jeon, M.J.; Ahn, C.H.; Kim, H.; Chung, I.J.; Jung, S.; Kim, H.-J.; Youn, J.K.; Kim, Y. The intratumoral administration of ferucarbotran conjugated with doxorubicin improved therapeutic effect by magnetic hyperthermia combined with pharmacotherapy in a hepatocellular carcinoma model. J. Exp. Clin. Cancer Res. 2014, 33, 57.
  8. Costa, L.A.A.; Mateus, M.; Borges, J.P.; Silva, J.C.; Barreiros, S.; Soares, P.I.P. Superparamagnetic Iron Oxide Nanozymes for Synergistic Cancer Treatment. Mater. Proc. 2022, 8, 3.
  9. Orozco-Henao, J.M.; Coral, D.F.; Muraca, D.; Moscoso-Londoño, O.; Mendoza Zélis, P.; van Raap, M.B.F.; Sharma, S.K.; Pirota, K.R.; Knobel, M. Effects of Nanostructure and Dipolar Interactions on Magnetohyperthermia in Iron Oxide Nanoparticles. J. Phys. Chem. C 2016, 120, 12796–12809.
  10. Santana, G.L.; Crovace, M.C.; Mazón, E.E.; de Oliveira, A.J.A.; Pavan, T.Z.; Zanotto, E.D. Smart Bone Graft Composite for Cancer Therapy Using Magnetic Hyperthermia. Materials 2022, 15, 3187.
  11. Mokhosi, S.R.; Mdlalose, W.; Nhlapo, A.; Singh, M. Advances in the Synthesis and Application of Magnetic Ferrite Nanoparticles for Cancer Therapy. Pharmaceutics 2022, 14, 937.
  12. Caizer, I.S.; Caizer, C. Superparamagnetic Hyperthermia Study with Cobalt Ferrite Nanoparticles Covered with γ-Cyclodextrins by Computer Simulation for Application in Alternative Cancer Therapy. Int. J. Mol. Sci. 2022, 23, 4350.
  13. Garanina, A.S.; Nikitin, A.A.; Abakumova, T.O.; Semkina, A.S.; Prelovskaya, A.O.; Naumenko, V.A.; Erofeev, A.S.; Gorelkin, P.V.; Majouga, A.G.; Abakumov, M.A.; et al. Cobalt Ferrite Nanoparticles for Tumor Therapy: Effective Heating versus Possible Toxicity. Nanomaterials 2022, 12, 38.
  14. Veres, T.; Voniatis, C.; Molnár, K.; Nesztor, D.; Fehér, D.; Ferencz, A.; Gresits, I.; Thuróczy, G.; Márkus, B.G.; Simon, F.; et al. An Implantable Magneto-Responsive Poly(aspartamide) Based Electrospun Scaffold for Hyperthermia Treatment. Nanomaterials 2022, 12, 1476.
  15. Minuti, A.E.; Stoian, G.; Herea, D.-D.; Radu, E.; Lupu, N.; Chiriac, H. Fe-Cr-Nb-B Ferrofluid for Biomedical Applications. Nanomaterials 2022, 12, 1488.
  16. Qu, Y.; Wang, Z.; Sun, M.; Zhao, T.; Zhu, X.; Deng, X.; Zhang, M.; Xu, Y.; Liu, H. A Theranostic Nanocomplex Combining with Magnetic Hyperthermia for Enhanced Accumulation and Efficacy of pH-Triggering Polymeric Cisplatin (IV) Prodrugs. Pharmaceuticals 2022, 15, 480.
  17. Proenca, M.P. Multifunctional Magnetic Nanowires and Nanotubes. Nanomaterials 2022, 12, 1308.
  18. Yu, J.; Cao, C.; Fang, F.; Pan, Y. Enhanced Magnetic Hyperthermia of Magnetoferritin through Synthesis at Elevated Temperature. Int. J. Mol. Sci. 2022, 23, 4012.
  19. Tsamos, D.; Krestou, A.; Papagiannaki, M.; Maropoulos, S. An Overview of the Production of Magnetic Core-Shell Nanoparticles and Their Biomedical Applications. Metals 2022, 12, 605.
  20. Songca, S.P.; Adjei, Y. Applications of Antimicrobial Photodynamic Therapy against Bacterial Biofilms. Int. J. Mol. Sci. 2022, 23, 3209.
  21. Perecin, C.J.; Gratens, X.P.M.; Chitta, V.A.; Leo, P.; de Oliveira, A.M.; Yoshioka, S.A.; Cerize, N.N.P. Synthesis and Characterization of Magnetic Composite Theragnostics by Nano Spray Drying. Materials 2022, 15, 1755.
  22. Ribeiro, B.C.; Alvarez, C.A.R.; Alves, B.C.; Rodrigues, J.M.; Queiroz, M.J.R.P.; Almeida, B.G.; Pires, A.; Pereira, A.M.; Araújo, J.P.; Coutinho, P.J.G.; et al. Development of Thermo- and pH-Sensitive Liposomal Magnetic Carriers for New Potential Antitumor Thienopyridine Derivatives. Materials 2022, 15, 1737.
  23. Ferdows, M.; Alam, J.; Murtaza, G.; Tzirtzilakis, E.E.; Sun, S. Biomagnetic Flow with CoFe2O4 Magnetic Particles through an Unsteady Stretching/Shrinking Cylinder. Magnetochemistry 2022, 8, 27.
  24. Alkahtani, M.; Zharkov, D.K.; Leontyev, A.V.; Shmelev, A.G.; Nikiforov, V.G.; Hemmer, P.R. Lightly Boron-Doped Nanodiamonds for Quantum Sensing Applications. Nanomaterials 2022, 12, 601.
  25. Pefanis, G.; Maniotis, N.; Tsiapla, A.-R.; Makridis, A.; Samaras, T.; Angelakeris, M. Numerical Simulation of Temperature Variations during the Application of Safety Protocols in Magnetic Particle Hyperthermia. Nanomaterials 2022, 12, 554.
  26. Maffei, M.E. Magnetic Fields and Cancer: Epidemiology, Cellular Biology, and Theranostics. Int. J. Mol. Sci. 2022, 23, 1339.
  27. Araujo, R.T.; Neta, M.S.B.; Coaquira, J.A.H.; Chaves, S.B.; Machado, F. A New Design for Magnetic Poly(vinyl pivalate) for Biomedical Applications: Synthesis, Characterization, and Evaluation of Cytotoxicity in Fibroblasts, Keratinocytes, and Human Melanoma Cells. Colloids Interfaces 2022, 6, 7.
  28. Caizer, C.; Caizer-Gaitan, I.S.; Watz, C.G.; Dehelean, C.A.; Bratu, T.; Soica, C. High Efficacy on the Death of Breast Cancer Cells Using SPMHT with Magnetite Cyclodextrins Nanobioconjugates. Pharmaceutics 2023, 15, 1145.
  29. Simões, B.T.; Almeida, F.V.; Borges, J.P.; Soares, P.I.P. Extracellular Hyperthermia for the Treatment of Advanced Cutaneous Melanoma. Materals Proc. 2022, 8, 56.
  30. García, J.; Gutiérrez, R.; González, A.S.; Jiménez-Ramirez, A.I.; Álvarez, Y.; Vega, V.; Reith, H.; Leistner, K.; Luna, C.; Nielsch, K.; et al. Exchange Bias Effect of (NiO,Ni(OH)2) Core/Shell Nanowires Synthesized by Electrochemical Deposition in Nanoporous Alumina Membranes. Int. J. Mol. Sci. 2023, 24, 7036.
  31. Montiel Schneider, M.G.; Martín, M.J.; Otarola, J.; Vakarelska, E.; Simeonov, V.; Lassalle, V.; Nedyalkova, M. Biomedical Applications of Iron Oxide Nanoparticles: Current Insights Progress and Perspectives. Pharmaceutics 2022, 14, 204.
  32. Healy, S.; Bakuzis, A.F.; Goodwill, P.W.; Attaluri, A.; Bulte, J.W.M.; Ivkov, R. Clinical magnetic hyperthermia requires integrated magnetic particle imaging. WIREs Nanomed. Nanobiotechnol. 2022, 14, e1779.
  33. Narayanaswamy, V.; Al-Omari, I.A.; Kamzin, A.S.; Issa, B.; Obaidat, I.M. Tailoring Interfacial Exchange Anisotropy in Hard–Soft Core-Shell Ferrite Nanoparticles for Magnetic Hyperthermia Applications. Nanomaterials 2022, 12, 262.
  34. Jiao, W.; Zhang, T.; Peng, M.; Yi, J.; He, Y.; Fan, H. Design of Magnetic Nanoplatforms for Cancer Theranostics. Biosensors 2022, 12, 38.
  35. Álvarez, E.; Estévez, M.; Gallo-Cordova, A.; González, B.; Castillo, R.R.; Morales, M.D.P.; Colilla, M.; Izquierdo-Barba, I.; Vallet-Regí, M. Superparamagnetic Iron Oxide Nanoparticles Decorated Mesoporous Silica Nanosystem for Combined Antibiofilm Therapy. Pharmaceutics 2022, 14, 163.
  36. Tran, H.-V.; Ngo, N.M.; Medhi, R.; Srinoi, P.; Liu, T.; Rittikulsittichai, S.; Lee, T.R. Multifunctional Iron Oxide Magnetic Nanoparticles for Biomedical Applications: A Review. Materials 2022, 15, 503.
  37. Blachowicz, T.; Hutten, A.; Ehrmann, A. Electromagnetic Interference Shielding with Electrospun Nanofiber Mats-A Review of Production, Physical Properties and Performance. Fibers 2022, 10, 47.
  38. Blachowicz, T.; Ehrmann, A. Most recent developments in electrospun magnetic nanofibers: A review. J. Eng. Fibers Fabr. 2020, 15, 1558925019900843.
  39. Storck, J.L.; Grothe, T.; Tuvshinbayar, K.; Diestelhorst, E.; Wehlage, D.; Brockhagen, B.; Wortmann, M.; Frese, N.; Ehrmann, A. Stabilization and Incipient Carbonization of Electrospun Polyacrylonitrile Nanofibers Fixated on Aluminum Substrates. Fibers 2020, 8, 55.
  40. Döpke, C.; Grothe, T.; Steblinski, P.; Klöcker, M.; Sabantina, L.; Kosmalska, D.; Blachowicz, T.; Ehrmann, A. Magnetic Nanofiber Mats for Data Storage and Transfer. Nanomaterials 2019, 9, 92.
  41. Blachowicz, T.; Grzybowski, J.; Steblinski, P.; Ehrmann, A. Neuro-Inspired Signal Processing in Ferromagnetic Nanofibers. Biomimetics 2021, 6, 32.
  42. Mu, Q.; Zhang, Q.; Yu, W.; Su, M.; Cai, Z.; Cui, K.; Ye, Y.; Liu, X.; Ding, L.; Chen, B.; et al. Robust Multiscale-Oriented Thermoresponsive Fibrous Hydrogels with Rapid Self-Recovery and Ultrafast Response Underwater. ACS Appl. Mater. Interfaces 2020, 12, 33152–33162.
  43. Mu, Q.; Zhang, Q.; Gao, L.; Chu, Z.; Cai, Z.; Zhang, X.; Wang, K.; Wei, Y. Structural Evolution and Formation Mechanism of the Soft Colloidal Arrays in the Core of PAAm Nanofibers by Electrospun Packing. Langmuir 2017, 33, 10291.
  44. Trabelsi, M.; Mamun, A.; Klöcker, M.; Moulefera, I.; Pljonkin, A.; Elleuch, K.; Sabantina, L. Magnetic Carbon Nanofiber Mats for Prospective Single Photon Avalanche Diode (SPAD) Sensing Applications. Sensors 2022, 21, 7873.
  45. Fokin, N.; Grothe, T.; Mamun, A.; Trabelsi, M.; Klöcker, M.; Sabantina, L.; Döpke, C.; Blachowicz, T.; Hütten, A.; Ehrmann, A. Magnetic properties of electrospun magnetic nanofiber mats after stabilization and carbonization. Materials 2020, 13, 1552.
  46. Blachowicz, T.; Grzybowski, J.; Ehrmann, A. Micromagnetic Simulations of Nanoparticles with Varying Amount of Agglomeration. Macromol. Symp. 2020, 402, 2100381.
  47. Hellert, C.; Wortmann, M.; Frese, N.; Grötsch, G.; Cornelißen, C.; Ehrmann, A. Adhesion of Electrospun Poly(acrylonitrile) Nanofibers on Conductive and Isolating Foil Substrates. Coatings 2021, 11, 249.
  48. Trabelsi, M.; Mamun, A.; Klöcker, M.; Sabantina, L.; Großerhode, C.; Blachowicz, T.; Ehrmann, A. Increased Mechanical Properties of Carbon Nanofiber Mats for Possible Medical Applications. Fibers 2019, 7, 98.
  49. Shabatina, T.I.; Vernaya, O.I.; Shimanovskiy, N.L.; Melnikov, M.Y. Metal and Metal Oxides Nanoparticles and Nanosystems in Anticancer and Antiviral Theragnostic Agents. Pharmaceutics 2023, 15, 1181.
  50. Kozior, T.; Mamun, A.; Trabelsi, M.; Wortmann, M.; Lilia, S.; Ehrmann, A. Electrospinning on 3D Printed Polymers for Mechanically Stabilized Filter Composites. Polymers 2019, 11, 2034.
  51. Kozior, T.; Trabelsi, M.; Mamun, A.; Sabantina, L.; Ehrmann, A. Stabilization of Electrospun Nanofiber Mats Used for Filters by 3D Printing. Polymers 2019, 11, 1618.
  52. Carvalho, A.; Gallo, J.; Pereira, D.M.; Valentão, P.; Andrade, P.B.; Hilliou, L.; Ferreira, P.M.T.; Bañobre-López, M.; Martins, J.A. Magnetic Dehydrodipeptide-Based Self-Assembled Hydrogels for Theragnostic Applications. Nanomaterials 2019, 9, 541.
  53. Peiravi, M.; Eslami, H.; Ansari, M.; Zare-Zardini, H. Magnetic hyperthermia: Potentials and limitations. J. Indian Chem. Soc. 2022, 99, 100269.
  54. Ji, Y.; Winter, L.; Navarro, L.; Ku, M.-C.; Periquito, J.S.; Pham, M.; Hoffmann, W.; Theune, L.E.; Calderón, M.; Niendorf, T. Controlled Release of Therapeutics from Thermoresponsive Nanogels: A Thermal Magnetic Resonance Feasibility Study. Cancers 2020, 12, 1380.
  55. Ganapathe, L.S.; Kazmi, J.; Mohamed, M.A.; Berhanuddin, D.D. Molarity Effects of Fe and NaOH on Synthesis and Characterisation of Magnetite (Fe3O4) Nanoparticles for Potential Application in Magnetic Hyperthermia Therapy. Magnetochemistry 2022, 8, 161.
  56. Salvador, M.; Marqués-Fernández, J.L.; Martínez-García, J.C.; Fiorani, D.; Arosio, P.; Avolio, M.; Brero, F.; Balanean, F.; Guerrini, A.; Sangregorio, C.; et al. Double-Layer Fatty Acid Nanoparticles as a Multiplatform for Diagnostics and Therapy. Nanomaterials 2022, 12, 205.
  57. Chan, M.-H.; Li, C.-H.; Chang, Y.-C.; Hsiao, M. Iron-Based Ceramic Composite Nanomaterials for Magnetic Fluid Hyperthermia and Drug Delivery. Pharmaceutics 2022, 14, 2584.
  58. Caizer, C. Computational Study Regarding CoxFe3−xO4 Ferrite Nanoparticles with Tunable Magnetic Properties in Superparamagnetic Hyperthermia for Effective Alternative Cancer Therapy. Nanomaterials 2021, 11, 3294.
  59. Nazarova, A.; Kozlovskiy, A.L.; Rusakov, V.S.; Egizbek, K.B.; Fadeev, M.S.; Prmantayeva, B.A.; Chudoba, D.; Zdorovets, M.V.; Kadyrzhanov, K.K. Study of the Applicability of Magnetic Iron-Containing Nanoparticles in Hyperthermia and Determination of Their Resistance to Degradation Processes. Crystals 2022, 12, 1816.
  60. Andrade, R.G.D.; Ferreira, D.; Veloso, S.R.S.; Santos-Pereira, C.; Castanheira, E.M.S.; Côrte-Real, M.; Rodrigues, L.R. Synthesis and Cytotoxicity Assessment of Citrate-Coated Calcium and Manganese Ferrite Nanoparticles for Magnetic Hyperthermia. Pharmaceutics 2022, 14, 2694.
  61. Cotin, G.; Kiefer, C.; Perton, F.; Ihiawakrim, D.; Blanco-Andujar, C.; Moldovan, S.; Lefevre, C.; Ersen, O.; Pichon, B.; Mertz, D.; et al. Unravelling the Thermal Decomposition Parameters for The Synthesis of Anisotropic Iron Oxide Nanoparticles. Nanomaterials 2018, 8, 881.
  62. Sadat, M.E.; Bud’ko, S.L.; Ewing, R.C.; Xu, H.; Pauletti, G.M.; Mast, D.B.; Shi, D. Effect of Dipole Interactions on Blocking Temperature and Relaxation Dynamics of Superparamagnetic Iron-Oxide (Fe3O4) Nanoparticle Systems. Materials 2023, 16, 496.
  63. Oltolina, F.; Peigneux, A.; Colangelo, D.; Clemente, N.; D’Urso, A.; Valente, G.; Iglesias, G.R.; Jiménez-Lopez, C.; Prat, M. Biomimetic Magnetite Nanoparticles as Targeted Drug Nanocarriers and Mediators of Hyperthermia in an Experimental Cancer Model. Cancers 2020, 12, 2564.
  64. Ragab, M.; Abouelregal, A.E.; AlShaibi, H.F.; Mansouri, R.A. Heat Transfer in Biological Spherical Tissues during Hyperthermia of Magnetoma. Biology 2021, 10, 1259.
  65. Zeinoun, M.; Domingo-Diez, J.; Rodriguez-Garcia, M.; Garcia, O.; Vasic, M.; Ramos, M.; Serrano Olmedo, J.J. Enhancing Magnetic Hyperthermia Nanoparticle Heating Efficiency with Non-Sinusoidal Alternating Magnetic Field Waveforms. Nanomaterials 2021, 11, 3240.
  66. McWilliams, B.T.; Wang, H.; Binns, V.J.; Curto, S.; Bossmann, S.H.; Prakash, P. Experimental Investigation of Magnetic Nanoparticle-Enhanced Microwave Hyperthermia. J. Funct. Biomater. 2017, 8, 21.
  67. Alromi, D.A.; Madani, S.Y.; Seifalian, A. Emerging Application of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer. Polymers 2021, 13, 4146.
  68. Wei, D.-H.; Pan, K.-Y.; Tong, S.-K. Surface Modification and Heat Generation of FePt Nanoparticles. Materials 2017, 10, 181.
  69. Matos, R.J.R.; Soares, P.I.P.; Silva, J.C.; Borges, J.P. Magnetic Bioactive Glass-Based 3D Systems for Bone Cancer Therapy and Regeneration. Mater. Proc. 2022, 8, 18.
  70. Sheng, L.; Zhu, X.; Sun, M.; Lan, Z.; Yang, Y.; Xin, Y.; Li, Y. Tumor Microenvironment-Responsive Magnetic Nanofluid for Enhanced Tumor MRI and Tumor multi-treatments. Pharmaceuticals 2023, 16, 166.
  71. Vangijzegem, T.; Lecomte, V.; Ternad, I.; Van Leuven, L.; Muller, R.N.; Stanicki, D.; Laurent, S. Superparamagnetic Iron Oxide Nanoparticles (SPION): From Fundamentals to State-of-the-Art Innovative Applications for Cancer Therapy. Pharmaceutics 2023, 15, 236.
  72. Caizer, C. Optimization Study on Specific Loss Power in Superparamagnetic Hyperthermia with Magnetite Nanoparticles for High Efficiency in Alternative Cancer Therapy. Nanomaterials 2021, 11, 40.
  73. Illés, E.; Tombácz, E.; Hegedűs, Z.; Szabó, T. Tunable Magnetic Hyperthermia Properties of Pristine and Mildly Reduced Graphene Oxide/Magnetite Nanocomposite Dispersions. Nanomaterials 2020, 10, 2426.
  74. Choi, S.K. Activation Strategies in Image-Guided Nanotherapeutic Delivery. J. Nanotheranostics 2020, 1, 78–104.
  75. Sahin, O.; Meiyazhagan, A.; Ajayan, P.M.; Krishnan, S. Immunogenicity of Externally Activated Nanoparticles for Cancer Therapy. Cancers 2020, 12, 3559.
  76. Khuyen, H.T.; Huong, T.T.; Van, N.D.; Huong, N.T.; Vu, N.; Lien, P.T.; Nam, P.H.; Nghia, V.X. Synthesis of Multifunctional Eu(III) Complex Doped Fe3O4/Au Nanocomposite for Dual Photo-Magnetic Hyperthermia and Fluorescence Bioimaging. Molecules 2023, 28, 749.
  77. Arsalani, S.; Arsalani, S.; Isikawa, M.; Guidelli, E.J.; Mazon, E.E.; Ramos, A.P.; Bakuzis, A.; Pavan, T.Z.; Baffa, O.; Carneiro, A.A.O. Hybrid Nanoparticles of Citrate-Coated Manganese Ferrite and Gold Nanorods in Magneto-Optical Imaging and Thermal Therapy. Nanomaterials 2023, 13, 434.
  78. Ghemes, C.; Dragos-Pinzaru, O.-G.; Tibu, M.; Lostun, M.; Lupu, N.; Chiriac, H. Tunnel Magnetoresistance-Based Sensor for Biomedical Application: Proof-of-Concept. Coatings 2023, 13, 227.
  79. Diab, D.E.H.; Clerc, P.; Serhan, N.; Fourmy, D.; Gigoux, V. Combined Treatments of Magnetic Intra-Lysosomal Hyperthermia with Doxorubicin Promotes Synergistic Anti-Tumoral Activity. Nanomaterials 2018, 8, 468.
  80. Osial, M.; Rybicka, P.; Pękała, M.; Cichowicz, G.; Cyrański, M.K.; Krysiński, P. Easy Synthesis and Characterization of Holmium-Doped SPIONs. Nanomaterials 2018, 8, 430.
  81. Arias, L.S.; Pessan, J.P.; Vieira, A.P.M.; Lima, T.M.T.D.; Delbem, A.C.B.; Monteiro, D.R. Iron Oxide Nanoparticles for Biomedical Applications: A Perspective on Synthesis, Drugs, Antimicrobial Activity, and Toxicity. Antibiotics 2018, 7, 46.
  82. Adam, A.; Mertz, D. Iron Silica Core-Shell Nanoparticles as Multimodal Platforms for Magnetic Resonance Imaging, Magnetic Hyperthermia, Near-Infrared Light Photothermia, and Drug Delivery. Nanomaterials 2023, 13, 1342.
  83. Salimi, M.; Sarkar, S.; Hashemi, M.; Saber, R. Treatment of Breast Cancer-Bearing BALB/c Mice with Magnetic Hyperthermia using Dendrimer Functionalized Iron-Oxide Nanoparticles. Nanomaterials 2020, 10, 2310.
  84. Ting, C.-K.; Dhawan, U.; Tseng, C.-L.; Alex Gong, C.-S.; Liu, W.-C.; Tsai, H.-D.; Chung, R.-J. Hyperthermia-Induced Controlled Local Anesthesia Administration Using Gelatin-Coated Iron–Gold Alloy Nanoparticles. Pharmaceutics 2020, 12, 1097.
  85. Stadler, B.J.H.; Reddy, M.; Basantkumar, R.; McGary, P.; Estrine, E.; Huang, X.; Sung, S.Y.; Tan, L.; Zou, J.; Maqableh, M.; et al. Galfenol Thin Films and Nanowires. Sensors 2018, 18, 2643.
  86. Yadel, C.; Michel, A.; Casale, S.; Fresnais, J. Hyperthermia Efficiency of Magnetic Nanoparticles in Dense Aggregates of Cerium Oxide/Iron Oxide Nanoparticles. Appl. Sci. 2018, 8, 1241.
  87. Albarqi, H.A.; Demessie, A.A.; Sabei, F.Y.; Moses, A.S.; Hansen, M.N.; Dhagat, P.; Taratula, O.R.; Taratula, O. Systemically Delivered Magnetic Hyperthermia for Prostate Cancer Treatment. Pharmaceutics 2020, 12, 1020.
  88. Attanayake, S.B.; Chanda, A.; Hulse, T.; Das, R.; Phan, M.-H.; Srikanth, H. Competing Magnetic Interactions and Field-Induced Metamagnetic Transition in Highly Crystalline Phase-Tunable Iron Oxide Nanorods. Nanomaterials 2023, 13, 1340.
  89. Tavares, F.J.T.M.; Soares, P.I.P.; Silva, J.C.; Borges, J.P. Preparation and In Vitro Characterization of Magnetic CS/PVA/HA/pSPIONs Scaffolds for Magnetic Hyperthermia and Bone Regeneration. Int. J. Mol. Sci. 2023, 24, 1128.
  90. Meneses-Brassea, B.P.; Borrego, E.A.; Blazer, D.S.; Sanad, M.F.; Pourmiri, S.; Gutierrez, D.A.; Varela-Ramirez, A.; Hadjipanayis, G.C.; El-Gendy, A.A. Ni-Cu Nanoparticles and Their Feasibility for Magnetic Hyperthermia. Nanomaterials 2020, 10, 1988.
  91. Medina, M.A.; Oza, G.; Ángeles-Pascual, A.; González, M.M.; Antaño-López, R.; Vera, A.; Leija, L.; Reguera, E.; Arriaga, L.G.; Hernández Hernández, J.M.; et al. Synthesis, Characterization and Magnetic Hyperthermia of Monodispersed Cobalt Ferrite Nanoparticles for Cancer Therapeutics. Molecules 2020, 25, 4428.
  92. Simeonidis, K.; Kaprara, E.; Rivera-Gil, P.; Xu, R.; Teran, F.J.; Kokkinos, E.; Mitropoulos, A.; Maniotis, N.; Balcells, L. Hydrotalcite-Embedded Magnetite Nanoparticles for Hyperthermia-Triggered Chemotherapy. Nanomaterials 2021, 11, 1796.
  93. Gareev, K.G.; Grouzdev, D.S.; Kharitonskii, P.V.; Kosterov, A.; Koziaeva, V.V.; Sergienko, E.S.; Shevtsov, M.A. Magnetotactic Bacteria and Magnetosomes: Basic Properties and Applications. Magnetochemistry 2021, 7, 86.
  94. Caizer, C. Theoretical Study on Specific Loss Power and Heating Temperature in CoFe2O4 Nanoparticles as Possible Candidate for Alternative Cancer Therapy by Superparamagnetic Hyperthemia. Appl. Sci. 2021, 11, 5505.
  95. Das, R.; Masa, J.A.; Kalappattil, V.; Nemati, Z.; Rodrigo, I.; Garaio, E.; García, J.Á.; Phan, M.-H.; Srikanth, H. Iron Oxide Nanorings and Nanotubes for Magnetic Hyperthermia: The Problem of Intraparticle Interactions. Nanomaterials 2021, 11, 1380.
  96. de la Parte, B.H.; Irazola, M.; Pérez-Muñoz, J.; Rodrigo, I.; Iturrizaga Correcher, S.; Mar Medina, C.; Castro, K.; Etxebarria, N.; Plazaola, F.; García, J.Á.; et al. Biochemical and Metabolomic Changes after Electromagnetic Hyperthermia Exposure to Treat Colorectal Cancer Liver Implants in Rats. Nanomaterials 2021, 11, 1318.
  97. Ortega-Muñoz, M.; Plesselova, S.; Delgado, A.V.; Santoyo-Gonzalez, F.; Salto-Gonzalez, R.; Giron-Gonzalez, M.D.; Iglesias, G.R.; López-Jaramillo, F.J. Poly(ethylene-imine)-Functionalized Magnetite Nanoparticles Derivatized with Folic Acid: Heating and Targeting Properties. Polymers 2021, 13, 1599.
  98. Fatima, H.; Charinpanitkul, T.; Kim, K.-S. Fundamentals to Apply Magnetic Nanoparticles for Hyperthermia Therapy. Nanomaterials 2021, 11, 1203.
  99. Moacă, E.-A.; Watz, C.-G.; Socoliuc, V.; Racoviceanu, R.; Păcurariu, C.; Ianoş, R.; Cîntă-Pînzaru, S.; Tudoran, L.B.; Nekvapil, F.; Iurciuc, S.; et al. Biocompatible Magnetic Colloidal Suspension Used as a Tool for Localized Hyperthermia in Human Breast Adenocarcinoma Cells: Physicochemical Analysis and Complex In Vitro Biological Profile. Nanomaterials 2021, 11, 1189.
  100. Jabalera, Y.; Sola-Leyva, A.; Carrasco-Jiménez, M.P.; Iglesias, G.R.; Jimenez-Lopez, C. Synergistic Photothermal-Chemotherapy Based on the Use of Biomimetic Magnetic Nanoparticles. Pharmaceutics 2021, 13, 625.
  101. Saikova, S.; Pavlikov, A.; Trofimova, T.; Mikhlin, Y.; Karpov, D.; Asanova, A.; Grigoriev, Y.; Volochaev, M.; Samoilo, A.; Zharkov, S.; et al. Hybrid Nanoparticles Based on Cobalt Ferrite and Gold: Preparation and Characterization. Metals 2021, 11, 705.
  102. Darwish, M.S.A.; Kim, H.; Bui, M.P.; Le, T.-A.; Lee, H.; Ryu, C.; Lee, J.Y.; Yoon, J. The Heating Efficiency and Imaging Performance of Magnesium Iron Ammonium Hydroxide Nanoparticles for Biomedical Applications. Nanomaterials 2021, 11, 1096.
  103. Rivera-Chaverra, M.J.; Restrepo-Parra, E.; Acosta-Medina, C.D.; Mello, A.; Ospina, R. Synthesis of Oxide Iron Nanoparticles Using Laser Ablation for Possible Hyperthermia Applications. Nanomaterials 2020, 10, 2099.
  104. Nemec, S.; Kralj, S.; Wilhelm, C.; Abou-Hassan, A.; Rols, M.-P.; Kolosnjaj-Tabi, J. Comparison of Iron Oxide Nanoparticles in Photothermia and Magnetic Hyperthermia: Effects of Clustering and Silica Encapsulation on Nanoparticles’ Heating Yield. Appl. Sci. 2020, 10, 7322.
  105. Ajinkya, N.; Yu, X.; Kaithal, P.; Luo, H.; Somani, P.; Ramakrishna, S. Magnetic Iron Oxide Nanoparticle (IONP) Synthesis to Applications: Present and Future. Materials 2020, 13, 4644.
  106. Schneider-Futschik, E.K.; Reyes-Ortega, F. Advantages and Disadvantages of Using Magnetic Nanoparticles for the Treatment of Complicated Ocular Disorders. Pharmaceutics 2021, 13, 1157.
  107. Sanad, M.F.; Meneses-Brassea, B.P.; Blazer, D.S.; Pourmiri, S.; Hadjipanayis, G.C.; El-Gendy, A.A. Superparamagnetic Fe/Au Nanoparticles and Their Feasibility for Magnetic Hyperthermia. Appl. Sci. 2021, 11, 6637.
  108. Xue, Y.; Lofland, S.; Hu, X. Comparative Study of Silk-Based Magnetic Materials: Effect of Magnetic Particle Types on the Protein Structure and Biomaterial Properties. Int. J. Mol. Sci. 2020, 21, 7583.
  109. Reichel, V.E.; Matuszak, J.; Bente, K.; Heil, T.; Kraupner, A.; Dutz, S.; Cicha, I.; Faivre, D. Magnetite-Arginine Nanoparticles as a Multifunctional Biomedical Tool. Nanomaterials 2020, 10, 2014.
  110. Khan, U.; Zaib, A.; Ishak, A. Magnetic Field Effect on Sisko Fluid Flow Containing Gold Nanoparticles through a Porous Curved Surface in the Presence of Radiation and Partial Slip. Mathematics 2021, 9, 921.
  111. Vurro, F.; Jabalera, Y.; Mannucci, S.; Glorani, G.; Sola-Leyva, A.; Gerosa, M.; Romeo, A.; Romanelli, M.G.; Malatesta, M.; Calderan, L.; et al. Improving the Cellular Uptake of Biomimetic Magnetic Nanoparticles. Nanomaterials 2021, 11, 766.
  112. Baino, F.; Fiume, E.; Miola, M.; Leone, F.; Onida, B.; Laviano, F.; Gerbaldo, R.; Verné, E. Fe-Doped Sol-Gel Glasses and Glass-Ceramics for Magnetic Hyperthermia. Materials 2018, 11, 173.
  113. Slavu, L.M.; Rinaldi, R.; Di Corato, R. Application in Nanomedicine of Manganese-Zinc Ferrite Nanoparticles. Appl. Sci. 2021, 11, 11183.
  114. Zhao, S.; Lee, S. Biomaterial-Modified Magnetic Nanoparticles γ-Fe2O3, Fe3O4 Used to Improve the Efficiency of Hyperthermia of Tumors in HepG2 Model. Appl. Sci. 2021, 11, 11124.
  115. Spoială, A.; Ilie, C.-I.; Crăciun, L.N.; Ficai, D.; Ficai, A.; Andronescu, E. Magnetite-Silica Core/Shell Nanostructures: From Surface Functionalization towards Biomedical Applications—A Review. Appl. Sci. 2021, 11, 11075.
  116. Cho, M.; Cervadoro, A.; Ramirez, M.R.; Stigliano, C.; Brazdeikis, A.; Colvin, V.L.; Civera, P.; Key, J.; Decuzzi, P. Assembly of Iron Oxide Nanocubes for Enhanced Cancer Hyperthermia and Magnetic Resonance Imaging. Nanomaterials 2017, 7, 72.
  117. Iacovita, C.; Florea, A.; Dudric, R.; Pall, E.; Moldovan, A.I.; Tetean, R.; Stiufiuc, R.; Lucaciu, C.M. Small versus Large Iron Oxide Magnetic Nanoparticles: Hyperthermia and Cell Uptake Properties. Molecules 2016, 21, 1357.
  118. de la Parte, B.H.; Rodrigo, I.; Gutiérrez-Basoa, J.; Iturrizaga Correcher, S.; Mar Medina, C.; Echevarría-Uraga, J.J.; Garcia, J.A.; Plazaola, F.; García-Alonso, I. Proposal of New Safety Limits for In Vivo Experiments of Magnetic Hyperthermia Antitumor Therapy. Cancers 2022, 14, 3084.
  119. Zverev, V.; Dobroserdova, A.; Kuznetsov, A.; Ivanov, A.; Elfimova, E. Computer Simulations of Dynamic Response of Ferrofluids on an Alternating Magnetic Field with High Amplitude. Mathematics 2021, 9, 2581.
  120. Nikolenko, P.I.; Nizamov, T.R.; Bordyuzhin, I.G.; Abakumov, M.A.; Baranova, Y.A.; Kovalev, A.D.; Shchetinin, I.V. Structure and Magnetic Properties of SrFe12−xInxO19 Compounds for Magnetic Hyperthermia Applications. Materials 2023, 16, 347.
  121. Baabu, P.R.S.; Kumar, H.K.; Gumpu, M.B.; Babu, K.J.; Kulandaisamy, A.J.; Rayappan, J.B.B. Iron Oxide Nanoparticles: A Review on the Province of Its Compounds, Properties and Biological Applications. Materials 2023, 16, 59.
  122. Dabaghi, M.; Rasa, S.M.M.; Cirri, E.; Ori, A.; Neri, F.; Quaas, R.; Hilger, I. Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice. Pharmaceutics 2021, 13, 1625.
  123. Baki, A.; Wiekhorst, F.; Bleul, R. Advances in Magnetic Nanoparticles Engineering for Biomedical Applications—A Review. Bioengineering 2021, 8, 134.
  124. Lemine, O.M.; Madkhali, N.; Alshammari, M.; Algessair, S.; Gismelseed, A.; El Mir, L.; Hjiri, M.; Yousif, A.A.; El-Boubbou, K. Maghemite (γ-Fe2O3) and γ-Fe2O3-TiO2 Nanoparticles for Magnetic Hyperthermia Applications: Synthesis, Characterization and Heating Efficiency. Materials 2021, 14, 5691.
  125. Kahil, H.; Faramawy, A.; El-Sayed, H.; Abdel-Sattar, A. Magnetic Properties and SAR for Gadolinium-Doped Iron Oxide Nanoparticles Prepared by Hydrothermal Method. Crystals 2021, 11, 1153.
  126. Caizer, C.; Caizer, I.S. Study on Maximum Specific Loss Power in Fe3O4 Nanoparticles Decorated with Biocompatible Gamma-Cyclodextrins for Cancer Therapy with Superparamagnetic Hyperthermia. Int. J. Mol. Sci. 2021, 22, 10071.
  127. Veloso, S.R.S.; Andrade, R.G.D.; Gomes, V.; Amorim, C.O.; Amaral, V.S.; Salgueiriño, V.; Coutinho, P.J.G.; Ferreira, P.M.T.; Correa-Duarte, M.A.; Castanheira, E.M.S. Oxidative Precipitation Synthesis of Calcium-Doped Manganese Ferrite Nanoparticles for Magnetic Hyperthermia. Int. J. Mol. Sci. 2022, 23, 14145.
  128. Korolev, D.V.; Shulmeyster, G.A.; Istomina, M.S.; Nikiforov, A.I.; Aleksandrov, I.V.; Semenov, V.G.; Galagudza, M.M. Indocyanine Green-Containing Magnetic Liposomes for Constant Magnetic Field-Guided Targeted Delivery and Theranostics. Magnetochemistry 2022, 8, 127.
  129. Mittal, A.; Roy, I.; Gandhi, S. Magnetic Nanoparticles: An Overview for Biomedical Applications. Magnetochemistry 2022, 8, 107.
  130. Arkaban, H.; Ebrahimi, A.K.; Yarahmadi, A.; Zarrintaj, P.; Barani, M. Development of a multifunctional system based on acid NPs conjugated to folic acid and loaded with doxorubicin for cancer theranostics. Nanotechnology 2021, 32, 305101.
  131. Iacoviță, C.; Fizeșan, I.; Nitica, S.; Florea, A.; Barbu-Tudoran, L.; Dudric, R.; Pop, A.; Vedeanu, N.; Crisan, O.; Tetean, R.; et al. Silica Coating of Ferromagnetic Iron Oxide Magnetic Nanoparticles Significantly Enhances Their Hyperthermia Performances for Efficiently Inducing Cancer Cells Death In Vitro. Pharmaceutics 2021, 13, 2026.
  132. Häring, M.; Schiller, J.; Mayr, J.; Grijalvo, S.; Eritja, R.; Díaz, D.D. Magnetic Gel Composites for Hyperthermia Cancer Therapy. Gels 2015, 1, 135–161.
  133. Zamora-Mora, V.; Soares, P.I.P.; Echeverria, C.; Hernández, R.; Mijangos, C. Composite Chitosan/Agarose Ferrogels for Potential Applications in Magnetic Hyperthermia. Gels 2015, 1, 69–80.
  134. Andrýsková, N.; Sourivong, P.; Babincová, M.; Šimaljaková, M. Controlled Release of Tazarotene from Magnetically Responsive Nanofiber Patch: Towards More Efficient Topical Therapy of Psoriasis. Appl. Sci. 2021, 11, 11022.
  135. Duong, H.D.T.; Nguyen, D.T.; Kim, K.-S. Effects of Process Variables on Properties of CoFe2O4 Nanoparticles Prepared by Solvothermal Process. Nanomaterials 2021, 11, 3056.
  136. Persano, S.; Vicini, F.; Poggi, A.; Fernandez, J.L.C.; Rizzo, G.M.R.; Gavilán, H.; Silvestri, N.; Pellegrino, T. Elucidating the Innate Immunological Effects of Mild Magnetic Hyperthermia on U87 Human Glioblastoma Cells: An In Vitro Study. Pharmaceutics 2021, 13, 1668.
  137. Manescu, V.; Paltanea, G.; Antoniac, I.; Vasilescu, M. Magnetic Nanoparticles Used in Oncology. Materials 2021, 14, 5948.
  138. Alkhayal, A.; Fathima, A.; Alhasan, A.H.; Alsharaeh, E.H. PEG Coated Fe3O4/RGO Nano-Cube-Like Structures for Cancer Therapy via Magnetic Hyperthermia. Nanomaterials 2021, 11, 2398.
  139. Jivago, J.L.P.R.; Brito, J.L.M.; Capistrano, G.; Vinícius-Araújo, M.; Lima Verde, E.; Bakuzis, A.F.; Souza, P.E.N.; Azevedo, R.B.; Lucci, C.M. New Prospects in Neutering Male Animals Using Magnetic Nanoparticle Hyperthermia. Pharmaceutics 2021, 13, 1465.
  140. Egea-Benavente, D.; Ovejero, J.G.; Morales, M.D.P.; Barber, D.F. Understanding MNPs Behaviour in Response to AMF in Biological Milieus and the Effects at the Cellular Level: Implications for a Rational Design That Drives Magnetic Hyperthermia Therapy toward Clinical Implementation. Cancers 2021, 13, 4583.
  141. Han, H.; Eigentler, T.W.; Wang, S.; Kretov, E.; Winter, L.; Hoffmann, W.; Grass, E.; Niendorf, T. Design, Implementation, Evaluation and Application of a 32-Channel Radio Frequency Signal Generator for Thermal Magnetic Resonance Based Anti-Cancer Treatment. Cancers 2020, 12, 1720.
  142. Piehler, S.; Dähring, H.; Grandke, J.; Göring, J.; Couleaud, P.; Aires, A.; Cortajarena, A.L.; Courty, J.; Latorre, A.; Somoza, Á.; et al. Iron Oxide Nanoparticles as Carriers for DOX and Magnetic Hyperthermia after Intratumoral Application into Breast Cancer in Mice: Impact and Future Perspectives. Nanomaterials 2020, 10, 1016.
  143. Chung, R.-J.; Shih, H.-T. Preparation of Multifunctional Core-Shell Nanoparticles with Surface Grafting as a Potential Treatment for Magnetic Hyperthermia. Materials 2014, 7, 653–661.
  144. Darwish, M.S.A.; Kim, H.; Lee, H.; Ryu, C.; Young Lee, J.; Yoon, J. Engineering Core-Shell Structures of Magnetic Ferrite Nanoparticles for High Hyperthermia Performance. Nanomaterials 2020, 10, 991.
  145. Cardoso, B.D.; Rodrigues, A.R.O.; Almeida, B.G.; Amorim, C.O.; Amaral, V.S.; Castanheira, E.M.S.; Coutinho, P.J.G. Stealth Magnetoliposomes Based on Calcium-Substituted Magnesium Ferrite Nanoparticles for Curcumin Transport and Release. Int. J. Mol. Sci. 2020, 21, 3641.
  146. Kudr, J.; Haddad, Y.; Richtera, L.; Heger, Z.; Cernak, M.; Adam, V.; Zitka, O. Magnetic Nanoparticles: From Design and Synthesis to Real World Applications. Nanomaterials 2017, 7, 243.
  147. Heid, S.; Unterweger, H.; Tietze, R.; Friedrich, R.P.; Weigel, B.; Cicha, I.; Eberbeck, D.; Boccaccini, A.R.; Alexiou, C.; Lyer, S. Synthesis and Characterization of Tissue Plasminogen Activator—Functionalized Superparamagnetic Iron Oxide Nanoparticles for Targeted Fibrin Clot Dissolution. Int. J. Mol. Sci. 2017, 18, 1837.
  148. Aram, E.; Moeni, M.; Abedizadeh, R.; Sabour, D.; Sadeghi-Abandansari, H.; Gardy, J.; Hassanpour, A. Smart and Multi-Functional Magnetic Nanoparticles for Cancer Treatment Applications: Clinical Challenges and Future Prospects. Nanomaterials 2022, 12, 3567.
  149. Kulikov, O.A.; Zharkov, M.N.; Ageev, V.P.; Yakobson, D.E.; Shlyapkina, V.I.; Zaborovskiy, A.V.; Inchina, V.I.; Balykova, L.A.; Tishin, A.M.; Sukhorukov, G.B.; et al. Magnetic Hyperthermia Nanoarchitectonics via Iron Oxide Nanoparticles Stabilised by Oleic Acid: Anti-Tumour Efficiency and Safety Evaluation in Animals with Transplanted Carcinoma. Int. J. Mol. Sci. 2022, 23, 4234.
  150. Ferreira, L.P.; Reis, C.P.; Robalo, T.T.; Melo Jorge, M.E.; Ferreira, P.; Gonçalves, J.; Hajalilou, A.; Cruz, M.M. Assisted Synthesis of Coated Iron Oxide Nanoparticles for Magnetic Hyperthermia. Nanomaterials 2022, 12, 1870.
  151. Dadfar, S.M.; Camozzi, D.; Darguzyte, M.; Roemhild, K.; Varvarà, P.; Metselaar, J.; Banala, S.; Straub, M.; Güvener, N.; Engelmann, U.; et al. Size-isolation of superparamagnetic iron oxide nanoparticles improves MRI, MPI and hyperthermia performance. J. Nanobiotechnol. 2020, 18, 22.
  152. Rodrigues, R.O.; Baldi, G.; Doumett, S.; Gallo, J.; Bañobre-López, M.; Dražić, G.; Calhelha, R.C.; Ferreira, I.C.F.R.; Lima, R.; Silva, A.M.T.; et al. A Tailor-Made Protocol to Synthesize Yolk-Shell Graphene-Based Magnetic Nanoparticles for Nanomedicine. C 2018, 4, 55.
  153. Gonçalves, J.; Ferreira, P.; Nunes, C. Development of Magnetic Chitosan Scaffolds with Potential for Bone Regeneration and Cancer Therapy. Mater. Proc. 2022, 8, 26.
  154. Giovannetti, G.; Frijia, F.; Flori, A. Radiofrequency Coils for Low-Field (0.18–0.55 T) Magnetic Resonance Scanners: Experience from a Research Lab–Manufacturing Companies Cooperation. Electronics 2022, 11, 4233.
  155. Freis, B.; Ramirez, M.D.L.A.; Kiefer, C.; Harlepp, S.; Iacovita, C.; Henoumont, C.; Affolter-Zbaraszczuk, C.; Meyer, F.; Mertz, D.; Boos, A.; et al. Effect of the Size and Shape of Dendronized Iron Oxide Nanoparticles Bearing a Targeting Ligand on MRI, Magnetic Hyperthermia, and Photothermia Properties—From Suspension to In Vitro Studies. Pharmaceutics 2023, 15, 1104.
  156. Atluri, R.; Atmaramani, R.; Tharaka, G.; McCallister, T.; Peng, J.; Diercks, D.; GhoshMitra, S.; Ghosh, S. Photo-Magnetic Irradiation-Mediated Multimodal Therapy of Neuroblastoma Cells Using a Cluster of Multifunctional Nanostructures. Nanomaterials 2018, 8, 774.
  157. Vargas, G.; Cypriano, J.; Correa, T.; Leão, P.; Bazylinski, D.A.; Abreu, F. Applications of Magnetotactic Bacteria, Magnetosomes and Magnetosome Crystals in Biotechnology and Nanotechnology: Mini-Review. Molecules 2018, 23, 2438.
  158. Liu, X.; Zhang, Y.; Wang, Y.; Zhu, W.; Li, G.; Ma, X.; Zhang, Y.; Chen, S.; Tiwari, S.; Shi, K.; et al. Comprehensive understanding of magnetic hyperthermia for improving antitumor therapeutic efficacy. Theranostics 2020, 10, 3793–3815.
  159. Zahn, D.; Landers, J.; Buchwald, J.; Diegel, M.; Salamon, S.; Müller, R.; Köhler, M.; Ecke, G.; Wende, H.; Dutz, S. Ferrimagnetic Large Single Domain Iron Oxide Nanoparticles for Hyperthermia Applications. Nanomaterials 2022, 12, 343.
  160. Veloso, S.R.S.; Ferreira, P.M.T.; Martins, J.A.; Coutinho, P.J.G.; Castanheira, E.M.S. Magnetogels: Prospects and Main Challenges in Biomedical Applications. Pharmaceutics 2018, 10, 145.
  161. Marassi, V.; Zanoni, I.; Ortelli, S.; Giordani, S.; Reschiglian, P.; Roda, B.; Zattoni, A.; Ravagli, C.; Cappiello, L.; Baldi, G.; et al. Native Study of the Behaviour of Magnetite Nanoparticles for Hyperthermia Treatment during the Initial Moments of Intravenous Administration. Pharmaceutics 2022, 14, 2810.
  162. Kaczmarek, K.; Hornowski, T.; Dobosz, B.; Józefczak, A. Influence of Magnetic Nanoparticles on the Focused Ultrasound Hyperthermia. Materials 2018, 11, 1607.
  163. Cervantes, O.; Lopez, Z.D.R.; Casillas, N.; Knauth, P.; Checa, N.; Cholico, F.A.; Hernandez-Gutiérrez, R.; Quintero, L.H.; Paz, J.A.; Cano, M.E. A Ferrofluid with Surface Modified Nanoparticles for Magnetic Hyperthermia and High ROS Production. Molecules 2022, 27, 544.
  164. Ferrero, R.; Barrera, G.; Celegato, F.; Vicentini, M.; Sözeri, H.; Yıldız, N.; Atila Dinçer, C.; Coïsson, M.; Manzin, A.; Tiberto, P. Experimental and Modelling Analysis of the Hyperthermia Properties of Iron Oxide Nanocubes. Nanomaterials 2021, 11, 2179.
  165. Chen, H.-A.; Lu, Y.-J.; Dash, B.S.; Chao, Y.-K.; Chen, J.-P. Hyaluronic Acid-Modified Cisplatin-Encapsulated Poly(Lactic-co-Glycolic Acid) Magnetic Nanoparticles for Dual-Targeted NIR-Responsive Chemo-Photothermal Combination Cancer Therapy. Pharmaceutics 2023, 15, 290.
  166. Shabatina, T.I.; Vernaya, O.I.; Shabatin, V.P.; Melnikov, M.Y. Magnetic Nanoparticles for Biomedical Purposes: Modern Trends and Prospects. Magnetochemistry 2020, 6, 30.
  167. Coene, A.; Leliaert, J. Simultaneous Coercivity and Size Determination of Magnetic Nanoparticles. Sensors 2020, 20, 3882.
  168. Puiu, R.A.; Balaure, P.C.; Constantinescu, E.; Grumezescu, A.M.; Andronescu, E.; Oprea, O.-C.; Vasile, B.S.; Grumezescu, V.; Negut, I.; Nica, I.C.; et al. Anti-Cancer Nanopowders and MAPLE-Fabricated Thin Films Based on SPIONs Surface Modified with Paclitaxel Loaded β-Cyclodextrin. Pharmaceutics 2021, 13, 1356.
  169. Habra, K.; McArdle, S.E.B.; Morris, R.H.; Cave, G.W.V. Synthesis and Functionalisation of Superparamagnetic Nano-Rods towards the Treatment of Glioblastoma Brain Tumours. Nanomaterials 2021, 11, 2157.
  170. Dias, A.M.M.; Courteau, A.; Bellaye, P.-S.; Kohli, E.; Oudot, A.; Doulain, P.-E.; Petitot, C.; Walker, P.-M.; Decréau, R.; Collin, B. Superparamagnetic Iron Oxide Nanoparticles for Immunotherapy of Cancers through Macrophages and Magnetic Hyperthermia. Pharmaceutics 2022, 14, 2388.
  171. Cao, T.-L.; Le, T.-A.; Hadadian, Y.; Yoon, J. Theoretical Analysis for Using Pulsed Heating Power in Magnetic Hyperthermia Therapy of Breast Cancer. Int. J. Mol. Sci. 2021, 22, 8895.
  172. Raouf, I.; Gas, P.; Kim, H.S. Numerical Investigation of Ferrofluid Preparation during In-Vitro Culture of Cancer Therapy for Magnetic Nanoparticle Hyperthermia. Sensors 2021, 21, 5545.
  173. Lafuente-Gómez, N.; Milán-Rois, P.; García-Soriano, D.; Luengo, Y.; Cordani, M.; Alarcón-Iniesta, H.; Salas, G.; Somoza, Á. Smart Modification on Magnetic Nanoparticles Dramatically Enhances Their Therapeutic Properties. Cancers 2021, 13, 4095.
  174. Carrey, J.; Mehdaoui, B.; Respaud, M. Simple models for dynamic hysteresis loop calculations of magnetic single-domain nanoparticles: Application to magnetic hyperthermia optimization. J. Appl. Phys. 2011, 109, 083921.
  175. Cardoso, B.D.; Rodrigues, A.R.O.; Bañobre-López, M.; Almeida, B.G.; Amorim, C.O.; Amaral, V.S.; Coutinho, P.J.G.; Castanheira, E.M.S. Magnetoliposomes Based on Shape Anisotropic Calcium/Magnesium Ferrite Nanoparticles as Nanocarriers for Doxorubicin. Pharmaceutics 2021, 13, 1248.
  176. Dhawan, U.; Tseng, C.-L.; Wang, H.-Y.; Hsu, S.-Y.; Tsai, M.-T.; Chung, R.-J. Assessing Suitability of Core/Shell Nanoparticle Geometry for Improved Theranostics in Colon Carcinoma. Nanomaterials 2021, 11, 2048.
  177. Fernández-Álvarez, F.; García-García, G.; Arias, J.L. A Tri-Stimuli Responsive (Maghemite/PLGA)/Chitosan Nanostructure with Promising Applications in Lung Cancer. Pharmaceutics 2021, 13, 1232.
  178. Ganguly, S.; Margel, S. Design of Magnetic Hydrogels for Hyperthermia and Drug Delivery. Polymers 2021, 13, 4259.
  179. Hazarika, K.P.; Borah, J.P. Biocompatible Tb doped Fe3O4 nanoparticles with enhanced heating efficiency for magnetic hyperthermia application. J. Magn. Magn. Mater. 2022, 560, 169597.
  180. Bañobre López, M.; Teijeiro, A.; Rivas, J. Magnetic nanoparticle based hyperthermia for cancer treatment. Rep. Pract. Oncol. Radiother. 2013, 18, 397–400.
  181. Zhong, Y.; Leung, V.; Wan, L.Y.; Dutz, S.; Ko, F.K.; Häfeli, U.O. Electrospun magnetic nanofibre mats—A new bondable biomaterial using remotely activated magnetic heating. J. Magn. Magn. Mater. 2015, 380, 330–334.
  182. Steblinski, P.; Blachowicz, T.; Ehrmann, A. Analysis of the energy distribution of iron nano-spheres for bit-patterned media. J. Magn. Magn. Mater. 2022, 562, 169805.
  183. Blachowicz, T.; Grzybowski, J.; Ehrmann, A. Influence of agglomerations on magnetic properties of polymer matrices filled with magnetic nanoparticles. Mater. Today Proc. 2022, 67, 792–796.
  184. Sapountzi, E.; Braiek, M.; Chateaux, J.-F.; Jaffrezic-Renault, N.; Lagarde, F. Recent Advances in Electrospun Nanofiber Interfaces for Biosensing Devices. Sensors 2017, 17, 1887.
  185. Eslami, P.; Albino, M.; Scavone, F.; Chiellini, F.; Morelli, A.; Baldi, G.; Cappiello, L.; Doumett, S.; Lorenzi, G.; Ravagli, C.; et al. Smart Magnetic Nanocarriers for Multi-Stimuli On-Demand Drug Delivery. Nanomaterials 2022, 12, 303.
  186. Tehrani, M.H.H.; Soltani, M.; Moradi Kashkooli, F.; Mahmoudi, M.; Raahemifar, K. Computational Modeling of Combination of Magnetic Hyperthermia and Temperature-Sensitive Liposome for Controlled Drug Release in Solid Tumor. Pharmaceutics 2022, 14, 35.
  187. Comanescu, C. Magnetic Nanoparticles: Current Advances in Nanomedicine, Drug Delivery and MRI. Chemistry 2022, 4, 872–930.
  188. Wang, Y.-J.; Lin, P.-Y.; Hsieh, S.-L.; Kirankumar, R.; Lin, H.-Y.; Li, J.-H.; Chen, Y.-T.; Wu, H.-M.; Hsieh, S. Utilizing Edible Agar as a Carrier for Dual Functional Doxorubicin-Fe3O4 Nanotherapy Drugs. Materials 2021, 14, 1824.
  189. Lachowicz, D.; Kaczyńska, A.; Wirecka, R.; Kmita, A.; Szczerba, W.; Bodzoń-Kułakowska, A.; Sikora, M.; Karewicz, A.; Zapotoczny, S. A Hybrid System for Magnetic Hyperthermia and Drug Delivery: SPION Functionalized by Curcumin Conjugate. Materials 2018, 11, 2388.
  190. Cardoso, B.D.; Cardoso, V.F.; Lanceros-Méndez, S.; Castanheira, E.M.S. Solid Magnetoliposomes as Multi-Stimuli-Responsive Systems for Controlled Release of Doxorubicin: Assessment of Lipid Formulations. Biomedicines 2022, 10, 1207.
  191. Nieciecka, D.; Rękorajska, A.; Cichy, D.; Końska, P.; Żuk, M.; Krysiński, P. Synthesis and Characterization of Magnetic Drug Carriers Modified with Tb3+ Ions. Nanomaterials 2022, 12, 795.
  192. Yu, Y.; Miyako, E. Alternating-Magnetic-Field-Mediated Wireless Manipulations of a Liquid Metal for Therapeutic Bioengineering. iScience 2018, 3, 134–148.
  193. Lim, E.-K.; Kim, T.; Paik, S.; Haam, S.; Huh, Y.-M.; Lee, K. Nanomaterials for Theranostics: Recent Advances and Future Challenges. Chem. Rev. 2015, 115, 327–394.
  194. Kumar, C.S.; Mohammad, F. Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery. Adv. Drug Deliv. Rev. 2011, 63, 789–808.
  195. Hayashi, K.; Tokuda, A.; Nakamura, J.; Sugawara-Narutaki, A.; Ohtsuki, C. Tearable and Fillable Composite Sponges Capable of Heat Generation and Drug Release in Response to Alternating Magnetic Field. Materials 2020, 13, 3637.
  196. Jabalera, Y.; Oltolina, F.; Peigneux, A.; Sola-Leyva, A.; Carrasco-Jiménez, M.P.; Prat, M.; Jimenez-Lopez, C.; Iglesias, G.R. Nanoformulation Design Including MamC-Mediated Biomimetic Nanoparticles Allows the Simultaneous Application of Targeted Drug Delivery and Magnetic Hyperthermia. Polymers 2020, 12, 1832.
  197. Contreras-Cáceres, R.; Cabeza, L.; Perazzoli, G.; Díaz, A.; López-Romero, J.M.; Melguizo, C.; Prados, J. Electrospun Nanofibers: Recent Applications in Drug Delivery and Cancer Therapy. Nanomaterials 2019, 9, 656.
  198. Bazzazzadeh, A.; Dizaji, B.F.; Kianinejad, N.; Nouri, A.; Irani, M. Fabrication of poly(acrylic acid) grafted-chitosan/polyurethane/magnetic MIL-53 metal organic framework composite core-shell nanofibers for co-delivery of temozolomide and paclitaxel against glioblastoma cancer cells. Int. J. Pharm. 2020, 587, 119674.
  199. Brennan, G.; Bergamino, S.; Pescio, M.; Tofail, S.A.M.; Silien, C. The Effects of a Varied Gold Shell Thickness on Iron Oxide Nanoparticle Cores in Magnetic Manipulation, T1 and T2 MRI Contrasting, and Magnetic Hyperthermia. Nanomaterials 2020, 10, 2424.
  200. Sandre, O.; Genevois, C.; Garaio, E.; Adumeau, L.; Mornet, S.; Couillaud, F. In Vivo Imaging of Local Gene Expression Induced by Magnetic Hyperthermia. Genes 2017, 8, 61.
  201. Wang, L.; Lai, S.-M.; Li, C.-Z.; Yu, H.-P.; Venkatesan, P.; Lai, P.-S. D-Alpha-Tocopheryl Poly(ethylene Glycol 1000) Succinate-Coated Manganese-Zinc Ferrite Nanomaterials for a Dual-Mode Magnetic Resonance Imaging Contrast Agent and Hyperthermia Treatments. Pharmaceutics 2022, 14, 1000.
  202. Griaznova, O.Y.; Belyaev, I.B.; Sogomonyan, A.S.; Zelepukin, I.V.; Tikhonowski, G.V.; Popov, A.A.; Komlev, A.S.; Nikitin, P.I.; Gorin, D.A.; Kabashin, A.V.; et al. Laser Synthesized Core-Satellite Fe-Au Nanoparticles for Multimodal In Vivo Imaging and In Vitro Photothermal Therapy. Pharmaceutics 2022, 14, 994.
  203. Christou, E.; Pearson, J.R.; Beltrán, A.M.; Fernández-Afonso, Y.; Gutiérrez, L.; de la Fuente, J.M.; Gámez, F.; García-Martín, M.L.; Caro, C. Iron–Gold Nanoflowers: A Promising Tool for Multimodal Imaging and Hyperthermia Therapy. Pharmaceutics 2022, 14, 636.
  204. Halicka, K.; Cabaj, J. Electrospun Nanofibers for Sensing and Biosensing Applications—A Review. Int. J. Mol. Sci. 2021, 22, 6357.
  205. Illés, E.; Szekeres, M.; Tóth, I.Y.; Farkas, K.; Földesi, I.; Szabó, Á.; Iván, B.; Tombácz, E. PEGylation of Superparamagnetic Iron Oxide Nanoparticles with Self-Organizing Polyacrylate-PEG Brushes for Contrast Enhancement in MRI Diagnosis. Nanomaterials 2018, 8, 776.
  206. Khizar, S.; Ahmad, N.M.; Ahmed, N.; Manzoor, S.; Hamayun, M.A.; Naseer, N.; Tenório, M.K.L.; Lebaz, N.; Elaissari, A. Aminodextran Coated CoFe2O4 Nanoparticles for Combined Magnetic Resonance Imaging and Hyperthermia. Nanomaterials 2020, 10, 2182.
  207. Islam, K.; Haque, M.; Kumar, A.; Hoq, A.; Hyder, F.; Hoque, S.M. Manganese Ferrite Nanoparticles (MnFe2O4): Size Dependence for Hyperthermia and Negative/Positive Contrast Enhancement in MRI. Nanomaterials 2020, 10, 2297.
  208. Han, X.; Li, Y.; Liu, W.; Chen, X.; Song, Z.; Wang, X.; Deng, Y.; Tang, X.; Jiang, Z. The Applications of Magnetic Particle Imaging: From Cell to Body. Diagnostics 2020, 10, 800.
  209. Billings, C.; Langley, M.; Warrington, G.; Mashali, F.; Johnson, J.A. Magnetic Particle Imaging: Current and Future Applications, Magnetic Nanoparticle Synthesis Methods and Safety Measures. Int. J. Mol. Sci. 2021, 22, 7651.
  210. Murase, K.; Mimura, A.; Banura, N.; Nishimoto, K.; Takata, H. Visualization of Magnetic Nanofibers Using Magnetic Particle Imaging. Open J. Med. Imaging 2015, 05, 56–65.
  211. Yu, E.Y.; Bishop, M.; Zheng, B.; Ferguson, R.M.; Khandhar, A.P.; Kemp, S.J.; Krishnan, K.M.; Goodwill, P.W.; Conolly, S.M. Magnetic Particle Imaging: A Novel in Vivo Imaging Platform for Cancer Detection. Nano Lett. 2017, 17, 1648–1654.
  212. Gleich, B.; Weizenecker, J. Tomographic imaging using the nonlinear response of magnetic particles. Nature 2015, 435, 1214–1217.
  213. Feddersen, T.V.; Hernandez-Tamames, J.A.; Franckena, M.; van Rhoon, G.C.; Paulides, M.M. Clinical Performance and Future Potential of Magnetic Resonance Thermometry in Hyperthermia. Cancers 2021, 13, 31.
  214. Strbak, O.; Antal, I.; Khmara, I.; Koneracka, M.; Kubovcikova, M.; Zavisova, V.; Molcan, M.; Jurikova, A.; Hnilicova, P.; Gombos, J.; et al. Influence of Dextran Molecular Weight on the Physical Properties of Magnetic Nanoparticles for Hyperthermia and MRI Applications. Nanomaterials 2020, 10, 2468.
  215. Do, H.D.; Ménager, C.; Michel, A.; Seguin, J.; Korichi, T.; Dhotel, H.; Marie, C.; Doan, B.-T.; Mignet, N. Development of Theranostic Cationic Liposomes Designed for Image-Guided Delivery of Nucleic Acid. Pharmaceutics 2020, 12, 854.
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