CYLD Gene

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1		Vivi Li	+ 751 word(s)	751	2020-12-15 07:49:33

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Li, V. CYLD Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4369 (accessed on 29 September 2026).

Li V. CYLD Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4369. Accessed September 29, 2026.

Li, Vivi. "CYLD Gene" Encyclopedia, https://encyclopedia.pub/entry/4369 (accessed September 29, 2026).

Li, V. (2020, December 23). CYLD Gene. In Encyclopedia. https://encyclopedia.pub/entry/4369

Li, Vivi. "CYLD Gene." Encyclopedia. Web. 23 December, 2020.

CYLD Gene

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/cyld

CYLD Lysine 63 Deubiquitinase

genes

References

Alameda JP, Fernández-Aceñero MJ, Moreno-Maldonado R, Navarro M, Quintana R,Page A, Ramírez A, Bravo A, Casanova ML. CYLD regulates keratinocytedifferentiation and skin cancer progression in humans. Cell Death Dis. 2011 Sep8;2:e208. doi: 10.1038/cddis.2011.82.
Almeida S, Maillard C, Itin P, Hohl D, Huber M. Five new CYLD mutations inskin appendage tumors and evidence that aspartic acid 681 in CYLD is essentialfor deubiquitinase activity. J Invest Dermatol. 2008 Mar;128(3):587-93.
Bignell GR, Warren W, Seal S, Takahashi M, Rapley E, Barfoot R, Green H, BrownC, Biggs PJ, Lakhani SR, Jones C, Hansen J, Blair E, Hofmann B, Siebert R, TurnerG, Evans DG, Schrander-Stumpel C, Beemer FA, van Den Ouweland A, Halley D,Delpech B, Cleveland MG, Leigh I, Leisti J, Rasmussen S. Identification of thefamilial cylindromatosis tumour-suppressor gene. Nat Genet. 2000 Jun;25(2):160-5.
Blake PW, Toro JR. Update of cylindromatosis gene (CYLD) mutations inBrooke-Spiegler syndrome: novel insights into the role of deubiquitination incell signaling. Hum Mutat. 2009 Jul;30(7):1025-36. doi: 10.1002/humu.21024.Review.
Dubois A, Rajan N. CYLD Cutaneous Syndrome. 2020 Apr 16. In: Adam MP, ArdingerHH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2020. Availablefrom http://www.ncbi.nlm.nih.gov/books/NBK555820/
Lee DA, Grossman ME, Schneiderman P, Celebi JT. Genetics of skin appendageneoplasms and related syndromes. J Med Genet. 2005 Nov;42(11):811-9. Review.
Massoumi R, Paus R. Cylindromatosis and the CYLD gene: new lessons on themolecular principles of epithelial growth control. Bioessays. 2007Dec;29(12):1203-14. Review.
Massoumi R. CYLD: a deubiquitination enzyme with multiple roles in cancer.Future Oncol. 2011 Feb;7(2):285-97. doi: 10.2217/fon.10.187. Review.
Massoumi R. Ubiquitin chain cleavage: CYLD at work. Trends Biochem Sci. 2010Jul;35(7):392-9. doi: 10.1016/j.tibs.2010.02.007.
Saggar S, Chernoff KA, Lodha S, Horev L, Kohl S, Honjo RS, Brandt HR, HartmannK, Celebi JT. CYLD mutations in familial skin appendage tumours. J Med Genet.2008 May;45(5):298-302. doi: 10.1136/jmg.2007.056127.
Sun SC. CYLD: a tumor suppressor deubiquitinase regulating NF-kappaBactivation and diverse biological processes. Cell Death Differ. 2010Jan;17(1):25-34. doi: 10.1038/cdd.2009.43. Review.
Young AL, Kellermayer R, Szigeti R, Tészás A, Azmi S, Celebi JT. CYLDmutations underlie Brooke-Spiegler, familial cylindromatosis, and multiplefamilial trichoepithelioma syndromes. Clin Genet. 2006 Sep;70(3):246-9.

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Subjects: Genetics & Heredity

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Update Date: 23 Dec 2020

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