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Xu, R. Multiple Endocrine Neoplasia. Encyclopedia. Available online: https://encyclopedia.pub/entry/4336 (accessed on 22 September 2026).
Xu R. Multiple Endocrine Neoplasia. Encyclopedia. Available at: https://encyclopedia.pub/entry/4336. Accessed September 22, 2026.
Xu, Rita. "Multiple Endocrine Neoplasia" Encyclopedia, https://encyclopedia.pub/entry/4336 (accessed September 22, 2026).
Xu, R. (2020, December 23). Multiple Endocrine Neoplasia. In Encyclopedia. https://encyclopedia.pub/entry/4336
Xu, Rita. "Multiple Endocrine Neoplasia." Encyclopedia. Web. 23 December, 2020.
Multiple Endocrine Neoplasia
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Multiple endocrine neoplasia is a group of disorders that affect the body's network of hormone-producing glands called the endocrine system. Hormones are chemical messengers that travel through the bloodstream and regulate the function of cells and tissues throughout the body. Multiple endocrine neoplasia typically involves tumors (neoplasia) in at least two endocrine glands; tumors can also develop in other organs and tissues. These growths can be noncancerous (benign) or cancerous (malignant). If the tumors become cancerous, the condition can be life-threatening.

genetic conditions

References

  1. Concolino P, Costella A, Capoluongo E. Multiple endocrine neoplasia type 1(MEN1): An update of 208 new germline variants reported in the last nine years.Cancer Genet. 2016 Jan-Feb;209(1-2):36-41. doi: 10.1016/j.cancergen.2015.12.002.
  2. Eng C. Multiple Endocrine Neoplasia Type 2. 1999 Sep 27 [updated 2019 Aug 15].In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington,Seattle; 1993-2020. Available from http://www.ncbi.nlm.nih.gov/books/NBK1257/
  3. Giusti F, Marini F, Brandi ML. Multiple Endocrine Neoplasia Type 1. 2005 Aug31 [updated 2017 Dec 14]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, BeanLJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA):University of Washington, Seattle; 1993-2020. Available fromhttp://www.ncbi.nlm.nih.gov/books/NBK1538/
  4. Lee M, Pellegata NS. Multiple endocrine neoplasia type 4. Front Horm Res.2013;41:63-78. doi: 10.1159/000345670.
  5. Moline J, Eng C. Multiple endocrine neoplasia type 2: an overview. Genet Med. 2011 Sep;13(9):755-64. doi: 10.1097/GIM.0b013e318216cc6d. Review.
  6. Pellegata NS. MENX and MEN4. Clinics (Sao Paulo). 2012;67 Suppl 1:13-8.Review.
  7. Raue F, Rondot S, Schulze E, Szpak-Ulczok S, Jarzab B, Frank-Raue K. Clinical utility gene card for: multiple endocrine neoplasia type 2. Eur J Hum Genet. 2012Jan;20(1). doi: 10.1038/ejhg.2011.142.
  8. Thakker RV, Newey PJ, Walls GV, Bilezikian J, Dralle H, Ebeling PR, Melmed S, Sakurai A, Tonelli F, Brandi ML; Endocrine Society. Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1). J Clin Endocrinol Metab. 2012Sep;97(9):2990-3011. doi: 10.1210/jc.2012-1230.
  9. Thakker RV. Multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4). Mol Cell Endocrinol. 2014 Apr 5;386(1-2):2-15. doi: 10.1016/j.mce.2013.08.002.
  10. Thakker RV. Multiple endocrine neoplasia type 1 (MEN1). Best Pract Res ClinEndocrinol Metab. 2010 Jun;24(3):355-70. doi: 10.1016/j.beem.2010.07.003. Review.
  11. Wells SA Jr, Asa SL, Dralle H, Elisei R, Evans DB, Gagel RF, Lee N, Machens A,Moley JF, Pacini F, Raue F, Frank-Raue K, Robinson B, Rosenthal MS, Santoro M,Schlumberger M, Shah M, Waguespack SG; American Thyroid Association GuidelinesTask Force on Medullary Thyroid Carcinoma. Revised American Thyroid Associationguidelines for the management of medullary thyroid carcinoma. Thyroid. 2015Jun;25(6):567-610. doi: 10.1089/thy.2014.0335. Review.
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Update Date: 23 Dec 2020
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