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Xu, R. Monoamine Oxidase A Deficiency. Encyclopedia. Available online: https://encyclopedia.pub/entry/4267 (accessed on 25 September 2026).
Xu R. Monoamine Oxidase A Deficiency. Encyclopedia. Available at: https://encyclopedia.pub/entry/4267. Accessed September 25, 2026.
Xu, Rita. "Monoamine Oxidase A Deficiency" Encyclopedia, https://encyclopedia.pub/entry/4267 (accessed September 25, 2026).
Xu, R. (2020, December 23). Monoamine Oxidase A Deficiency. In Encyclopedia. https://encyclopedia.pub/entry/4267
Xu, Rita. "Monoamine Oxidase A Deficiency." Encyclopedia. Web. 23 December, 2020.
Monoamine Oxidase A Deficiency
Edit

Monoamine oxidase A deficiency is a rare disorder that occurs almost exclusively in males. It is characterized by mild intellectual disability and behavioral problems beginning in early childhood.

genetic conditions

References

  1. Bortolato M, Shih JC. Behavioral outcomes of monoamine oxidase deficiency:preclinical and clinical evidence. Int Rev Neurobiol. 2011;100:13-42. doi:10.1016/B978-0-12-386467-3.00002-9. Review.
  2. Brunner HG, Nelen M, Breakefield XO, Ropers HH, van Oost BA. Abnormal behaviorassociated with a point mutation in the structural gene for monoamine oxidase A. Science. 1993 Oct 22;262(5133):578-80.
  3. Cases O, Seif I, Grimsby J, Gaspar P, Chen K, Pournin S, Müller U, Aguet M,Babinet C, Shih JC, et al. Aggressive behavior and altered amounts of brainserotonin and norepinephrine in mice lacking MAOA. Science. 1995 Jun23;268(5218):1763-6.
  4. Palmer EE, Leffler M, Rogers C, Shaw M, Carroll R, Earl J, Cheung NW, ChampionB, Hu H, Haas SA, Kalscheuer VM, Gecz J, Field M. New insights into Brunnersyndrome and potential for targeted therapy. Clin Genet. 2016 Jan;89(1):120-7.doi: 10.1111/cge.12589.
  5. Piton A, Poquet H, Redin C, Masurel A, Lauer J, Muller J, Thevenon J, HerengerY, Chancenotte S, Bonnet M, Pinoit JM, Huet F, Thauvin-Robinet C, Jaeger AS, LeGras S, Jost B, Gérard B, Peoc'h K, Launay JM, Faivre L, Mandel JL. 20 ans après:a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition. Eur J Hum Genet. 2014Jun;22(6):776-83. doi: 10.1038/ejhg.2013.243.
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Update Date: 23 Dec 2020
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