Intrahepatic cholestasis of pregnancy is a liver disorder that occurs in pregnant women.
genetic conditions
References
Bacq Y, Gendrot C, Perrotin F, Lefrou L, Chrétien S, Vie-Buret V, Brechot MC, Andres CR. ABCB4 gene mutations and single-nucleotide polymorphisms in women withintrahepatic cholestasis of pregnancy. J Med Genet. 2009 Oct;46(10):711-5. doi:10.1136/jmg.2009.067397.
Brouwers L, Koster MP, Page-Christiaens GC, Kemperman H, Boon J, Evers IM,Bogte A, Oudijk MA. Intrahepatic cholestasis of pregnancy: maternal and fetaloutcomes associated with elevated bile acid levels. Am J Obstet Gynecol. 2015Jan;212(1):100.e1-7. doi: 10.1016/j.ajog.2014.07.026.
Dixon PH, van Mil SW, Chambers J, Strautnieks S, Thompson RJ, Lammert F,Kubitz R, Keitel V, Glantz A, Mattsson LA, Marschall HU, Molokhia M, Moore GE,Linton KJ, Williamson C. Contribution of variant alleles of ABCB11 tosusceptibility to intrahepatic cholestasis of pregnancy. Gut. 2009Apr;58(4):537-44. doi: 10.1136/gut.2008.159541.
Geenes V, Chappell LC, Seed PT, Steer PJ, Knight M, Williamson C. Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population-based case-control study. Hepatology. 2014Apr;59(4):1482-91. doi: 10.1002/hep.26617.
Meier Y, Zodan T, Lang C, Zimmermann R, Kullak-Ublick GA, Meier PJ, Stieger B,Pauli-Magnus C. Increased susceptibility for intrahepatic cholestasis ofpregnancy and contraceptive-induced cholestasis in carriers of the 1331T>Cpolymorphism in the bile salt export pump. World J Gastroenterol. 2008 Jan7;14(1):38-45.
Pauli-Magnus C, Meier PJ, Stieger B. Genetic determinants of drug-inducedcholestasis and intrahepatic cholestasis of pregnancy. Semin Liver Dis. 2010May;30(2):147-59. doi: 10.1055/s-0030-1253224.
Williamson C, Geenes V. Intrahepatic cholestasis of pregnancy. Obstet Gynecol.2014 Jul;124(1):120-33. doi: 10.1097/AOG.0000000000000346. Review.
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