IL7R Gene

Version	Summary	Created by	Modification	Content Size	Created at	Operation
1		Dean Liu	+ 714 word(s)	714	2020-12-15 07:57:26

Cite

If you have any further questions, please contact Encyclopedia Editorial Office.

Select a Style

Liu, D. IL7R Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4177 (accessed on 12 September 2026).

Liu D. IL7R Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4177. Accessed September 12, 2026.

Liu, Dean. "IL7R Gene" Encyclopedia, https://encyclopedia.pub/entry/4177 (accessed September 12, 2026).

Liu, D. (2020, December 23). IL7R Gene. In Encyclopedia. https://encyclopedia.pub/entry/4177

Liu, Dean. "IL7R Gene." Encyclopedia. Web. 23 December, 2020.

IL7R Gene

Edit

This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/il7r

Interleukin 7 receptor

genes

References

Akashi K, Kondo M, Weissman IL. Role of interleukin-7 in T-cell developmentfrom hematopoietic stem cells. Immunol Rev. 1998 Oct;165:13-28. Review.
Corfe SA, Paige CJ. The many roles of IL-7 in B cell development; mediator of survival, proliferation and differentiation. Semin Immunol. 2012Jun;24(3):198-208. doi: 10.1016/j.smim.2012.02.001.
Giliani S, Mori L, de Saint Basile G, Le Deist F, Rodriguez-Perez C, Forino C,Mazzolari E, Dupuis S, Elhasid R, Kessel A, Galambrun C, Gil J, Fischer A,Etzioni A, Notarangelo LD. Interleukin-7 receptor alpha (IL-7Ralpha) deficiency: cellular and molecular bases. Analysis of clinical, immunological, and molecular features in 16 novel patients. Immunol Rev. 2005 Feb;203:110-26. Review.
Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ,Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA,Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL; MultipleSclerosis Genetics Group. Interleukin 7 receptor alpha chain (IL7R) shows allelicand functional association with multiple sclerosis. Nat Genet. 2007Sep;39(9):1083-91.
He R, Geha RS. Thymic stromal lymphopoietin. Ann N Y Acad Sci. 2010Jan;1183:13-24. doi: 10.1111/j.1749-6632.2009.05128.x. Review.
Lundmark F, Duvefelt K, Iacobaeus E, Kockum I, Wallström E, Khademi M, Oturai A, Ryder LP, Saarela J, Harbo HF, Celius EG, Salter H, Olsson T, Hillert J.Variation in interleukin 7 receptor alpha chain (IL7R) influences risk ofmultiple sclerosis. Nat Genet. 2007 Sep;39(9):1108-13.
Puel A, Ziegler SF, Buckley RH, Leonard WJ. Defective IL7R expression inT(-)B(+)NK(+) severe combined immunodeficiency. Nat Genet. 1998 Dec;20(4):394-7.
Shochat C, Tal N, Bandapalli OR, Palmi C, Ganmore I, te Kronnie G, Cario G,Cazzaniga G, Kulozik AE, Stanulla M, Schrappe M, Biondi A, Basso G, Bercovich D, Muckenthaler MU, Izraeli S. Gain-of-function mutations in interleukin-7receptor-α (IL7R) in childhood acute lymphoblastic leukemias. J Exp Med. 2011 May9;208(5):901-8. doi: 10.1084/jem.20110580.Med. 2011 Jun 6;208(6):1333. J Exp Med. 2011 May 9;208(5):preceding 901.
Zenatti PP, Ribeiro D, Li W, Zuurbier L, Silva MC, Paganin M, Tritapoe J,Hixon JA, Silveira AB, Cardoso BA, Sarmento LM, Correia N, Toribio ML, Kobarg J, Horstmann M, Pieters R, Brandalise SR, Ferrando AA, Meijerink JP, Durum SK, YunesJA, Barata JT. Oncogenic IL7R gain-of-function mutations in childhood T-cellacute lymphoblastic leukemia. Nat Genet. 2011 Sep 4;43(10):932-9. doi:10.1038/ng.924.

©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.

Upload a video for this entry

Information

Subjects: Genetics & Heredity

Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Dean Liu

View Times: 669

Entry Collection: MedlinePlus

Update Date: 23 Dec 2020

Table of Contents

Video Upload Options

References