Plastics have gained immense popularity in industry and modern life since their inception and subsequent mass production in the mid-1950s 
. The chemical structure of plastics enables the manufacture of useful products such as temperature- and chemical-resistant packaging and sturdy building materials (e.g., polyvinyl chloride [PVC] piping). The hydrophobic property of plastics makes them potential conveyors of dangerous substances such as polychlorinated biphenyls (PCBs) and persistent organic pollutants (POPs). Examples of some of the most common plastics are polyethylene terephthalate (PET), high density polyethylene (HDPE), low density polyethylene (LDPE), PVC, and polypropylene (PP). These plastics are used for a variety of products (e.g., piping, clothing, furniture, electronics, and implants).
As plastics weather in the environment, they fragment into progressively smaller pieces, mainly through physical-chemical breakdown. Plastics can also fragment through microbial degradation. This discovery, combined with the chemical properties of plastic, such as their hydrophobicity and ability to attract other hydrophobic particles, spurred an explosion of research into microplastics, beginning around 2015. A commonly adopted metric for classifying plastics as microplastics is if any dimension (length, width, or height) of the plastics being studied is 5 mm or less 
. Microplastics are also classified by origin as primary or secondary microplastics 
. Primary microplastics are plastics manufactured with a dimension of 5 mm or less, typical of the textile and pharmaceutical industries. Secondary microplastics are formed through weathering and fragmentation of plastic debris in the environment, such as plastic bags 
2. Microplastic Surgency
Five hundred and thirty-eight (94%) publications included were published within the period January 2015 through January 2020. The development of modern technologies, such as dynamic light scattering, Raman spectroscopy, transmission electron microscopy, hyperspectral microscopy, and mass- or size-based particle counters, have allowed for the identification, characterization, and study of small particles such as microplastics 
. Along with these advances in technology, environmental and political groups have made marked investments to invigorate the study of microplastics and bring them to the attention of the public 
Starting in the 1960s, plastic production increased annually by approximately 8.7% 
. Plastics infiltrated multiple sectors, including computing, food preparation, healthcare, and infrastructure 
. Novel uses for plastics have led to increased production. Plastic pollution has been a major environmental concern, both politically and scientifically.
Plastic pollution has been a major environmental concern, both politically and scientifically 
. Concern initially centered on macroplastics in the marine environment and their effects, such as plastic ingestion and entanglement of sea turtles 
. However, the focus expanded rapidly upon the discovery that plastics were breaking down into smaller microplastics. Instead of breaking down into environmentally usable carbon, macroplastics were becoming smaller microplastics that retained their relatively inert chemical properties 
. This discovery—coupled with the fact that the hydrophobic nature persists as plastics break down into their microplastic constituents—concerned scientists. Hydrophobicity allows harmful hydrophobic chemicals to adsorb to the plastics, and eventually enter the food chain leading to potential human exposure at the end of that chain. This process has spurred an international inquiry into microplastics 
3. Areas of Focus in the Screening Methodology
Measurable concentrations of microplastics have been detected in every ocean, including the Arctic Ocean 
, the North Pacific central gyre 
, the Black Sea 
, and in several major river systems around the world, such as the Amazon River 
. Microplastics absorption and adsorption properties in water have been studied more extensively than in any other media in the scoping review, with 94 [75%] of publications included in the absorption/adsorption category investigating microplastics in water. Water has been the main environmental medium of study of other review articles on microplastic literature 
. 440 [77%] of included publications examined microplastics in water. The pervasiveness of microplastics in water has implications for flora and fauna and for several worldwide industries. Over the past 5 years, scientists have developed a clearer understanding of microplastic presence in water.
Researchers have detected microplastics in land-based ecosystems, including beaches in Brazil 
, Sri Lanka 
, and islands in the Caribbean 
. Microplastics have been discovered in agricultural fields, where it has been detected in vegetable farmlands 
. The rate of microplastic use in farming increases every year because plastic mulch increases the water efficiency of soil, leading to higher crop yields 
. This practice shows little sign of letting up and reinforces the case for further research into the potential for human exposure to microplastics through ingestion of farmed products.
Because of their size, microplastics can mobilize as dust and disperse by wind to other environments 
. Dris et al. indicate between 29 and 280 particles m−2
for microplastic and microparticle atmospheric fallout. Atmospheric or airborne microplastics have been documented to remain in the lungs of people working in indoor industries such as textile factories 
. Synthetic clothing potentially can add to airborne inhalation exposure in the indoor environment 
. Studies have described microplastics in urban environments in major cities such as Paris, France, where they have been identified in wastewater, atmospheric fallout, and surface water. The detection of microplastics in certain industries and within the home is an indication that future research should include more airborne studies to determine the threat to humans of airborne microplastics exposure.
33% of publications focused on microplastics in food and food sources. Food should be closely monitored with respect to new potential threats to human safety. The pervasiveness of microplastics in the water environment, as discussed above, has led to several studies focusing on the commercial fish market. Microplastics have been identified in fisheries in the Maowei Sea, 
fisheries in China 
, and estuaries in Florida 
. Microplastics have been detected in table salt 
, bottled mineral water 
, and beer 
. Studying microplastics in various food sources will continue to yield valuable information for assessing exposure in different diets.
3.5. Measuring Protocol
The majority of included papers (83%) described protocols for gathering, isolating, and quantifying microplastics. Microplastics usually are collected from water surfaces such as lakes and oceans using fine mesh or plankton nets 
. Microplastics are commonly collected from beach and sediment environments using trowels to collect surface sediment samples 
. Raman, micro-Raman, micro-Fourier-transform infrared spectroscopy, and macroscopic dimensioned near infrared in combination with chemometrics and hyperspectral imaging technology are used to identify microplastics 
. Visualization techniques such as physical separation using microscopes, or the naked eye are also used to identify microplastics 
. The future of microplastics detection and understanding is advancing as innovations in spectroscopy and other scientific fields, allowing scientists to study plastics at the nano level 
3.6. Microplastics Ingestion
Understanding microplastic ingestion is critical to helping determine human exposure risk and creating risk assessment. This reveals that very little literature exists on human ingestion and exposure, but the scoping review did yield work addressing ingestion across the trophic range. Literature shows evidence of microplastic ingestion in higher trophic level organisms, including the auk (an arctic sea bird) 
, basking sharks, and fin whales 
. Additionally, microplastics are present in food items, with evidence that all human study subjects tested positive for microplastics in their stool samples 
3.7. Geospatial Analysis
Geospatial descriptions help people understand how microplastics mobilize and settle in a variety of environments. Geospatial analysis can come in the form of displaying specific latitude and longitude of sample collections in a study 
. These spatial analyses show that certain fish that support seafaring economies are also located in areas contaminated with microplastics. This highlights the increased potential for exposures to microplastics among those societies consuming these fish regularly 
. These tools can allow researchers to track the mobilization of plastics across large areas to better understand how the movement and sequestration of plastics can affect human health 
3.8. Trophic Transfer
The trophic transfer of microplastics is the ability for microplastics to move through the food web from lower trophic levels to higher trophic levels. Relatively few studies delve into trophic transfer in the environment. Literature identified in the scoping review used mussels as a model to illustrate the potential for trophic transfer 
and a few described the potential for trophic transfer between crustaceans and fish 
. Other studies indicate that microplastics do not biomagnify through the trophic levels 
. Whether trophic transfer of microplastics is occurring remains unclear. More research is needed to understand the effects on human exposure to microplastics associated with consumption of animals and plants throughout the trophic levels.
4. Human Exposure Category
The first stage of the abstract screening process identified 16 (1.3%) papers to be placed in the human exposure category, one of the main objectives for the scoping review. Only 11 of the articles were included in the final scoping review. In 2019, five published research articles dealt with human exposure, a possible indicator that research might be trending toward human exposure investigations. Articles such as that by Zarus et al. 
, describe a variety of human exposures to microplastics, specifically showing particular organ targets. According to Zarus et al. there is sufficient characterization to demonstrate that elements of exposure exist in both the lungs and immune systems. There is also emerging evidence of characterization of exposure in the neurologic, gastrointestinal, and hepatic systems 
. Polypropylene and polyethylene terephthalate were detected in all stool samples from a study conducted by Schwabl et al. 
. The articles highlight industrial and nonindustrial exposures and the need for more studies of industrial and environmental microplastic exposures. Two objectives were to identify research trends and to identify accomplishments related to the assessment and quantification of human exposure to microplastics. The authors intend to use this information to develop next steps related to assessing and quantifying human exposure.