HTT Gene

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1		Dean Liu	+ 500 word(s)	500	2020-12-15 07:57:00

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Liu, D. HTT Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4127 (accessed on 25 September 2026).

Liu D. HTT Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4127. Accessed September 25, 2026.

Liu, Dean. "HTT Gene" Encyclopedia, https://encyclopedia.pub/entry/4127 (accessed September 25, 2026).

Liu, D. (2020, December 23). HTT Gene. In Encyclopedia. https://encyclopedia.pub/entry/4127

Liu, Dean. "HTT Gene." Encyclopedia. Web. 23 December, 2020.

HTT Gene

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/htt

Huntingtin

genes

References

Bates G. Huntingtin aggregation and toxicity in Huntington's disease. Lancet. 2003 May 10;361(9369):1642-4. Review.
Borrell-Pagès M, Zala D, Humbert S, Saudou F. Huntington's disease: fromhuntingtin function and dysfunction to therapeutic strategies. Cell Mol Life Sci.2006 Nov;63(22):2642-60. Review.
Cattaneo E. Dysfunction of wild-type huntingtin in Huntington disease. NewsPhysiol Sci. 2003 Feb;18:34-7. Review.
Gárdián G, Vécsei L. Huntington's disease: pathomechanism and therapeuticperspectives. J Neural Transm (Vienna). 2004 Oct;111(10-11):1485-94. Review.
Imarisio S, Carmichael J, Korolchuk V, Chen CW, Saiki S, Rose C, Krishna G,Davies JE, Ttofi E, Underwood BR, Rubinsztein DC. Huntington's disease: frompathology and genetics to potential therapies. Biochem J. 2008 Jun1;412(2):191-209. doi: 10.1042/BJ20071619. Review.
Jones L, Hughes A. Pathogenic mechanisms in Huntington's disease. Int RevNeurobiol. 2011;98:373-418. doi: 10.1016/B978-0-12-381328-2.00015-8. Review.
Landles C, Bates GP. Huntingtin and the molecular pathogenesis of Huntington'sdisease. Fourth in molecular medicine review series. EMBO Rep. 2004Oct;5(10):958-63. Review.
Li SH, Li XJ. Huntingtin and its role in neuronal degeneration.Neuroscientist. 2004 Oct;10(5):467-75. Review.
MacDonald ME. Huntingtin: alive and well and working in middle management. SciSTKE. 2003 Nov 4;2003(207):pe48. Review.
Maiuri T, Mocle AJ, Hung CL, Xia J, van Roon-Mom WM, Truant R. Huntingtin is ascaffolding protein in the ATM oxidative DNA damage response complex. Hum MolGenet. 2017 Jan 15;26(2):395-406. doi: 10.1093/hmg/ddw395.
Rangone H, Humbert S, Saudou F. Huntington's disease: how does huntingtin, an anti-apoptotic protein, become toxic? Pathol Biol (Paris). 2004 Jul;52(6):338-42.Review.
Slow EJ, Graham RK, Hayden MR. To be or not to be toxic: aggregations inHuntington and Alzheimer disease. Trends Genet. 2006 Aug;22(8):408-11.
van Dellen A, Grote HE, Hannan AJ. Gene-environment interactions, neuronaldysfunction and pathological plasticity in Huntington's disease. Clin ExpPharmacol Physiol. 2005 Dec;32(12):1007-19. Review.
Young AB. Huntingtin in health and disease. J Clin Invest. 2003Feb;111(3):299-302. Review.

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Subjects: Genetics & Heredity

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Update Date: 23 Dec 2020

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