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Liu, D. HTRA1 Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4125 (accessed on 29 September 2026).
Liu D. HTRA1 Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4125. Accessed September 29, 2026.
Liu, Dean. "HTRA1 Gene" Encyclopedia, https://encyclopedia.pub/entry/4125 (accessed September 29, 2026).
Liu, D. (2020, December 23). HTRA1 Gene. In Encyclopedia. https://encyclopedia.pub/entry/4125
Liu, Dean. "HTRA1 Gene." Encyclopedia. Web. 23 December, 2020.
HTRA1 Gene
Edit

HtrA serine peptidase 1

genes

References

  1. An E, Sen S, Park SK, Gordish-Dressman H, Hathout Y. Identification of novelsubstrates for the serine protease HTRA1 in the human RPE secretome. InvestOphthalmol Vis Sci. 2010 Jul;51(7):3379-86. doi: 10.1167/iovs.09-4853.
  2. Chien J, Ota T, Aletti G, Shridhar R, Boccellino M, Quagliuolo L, Baldi A,Shridhar V. Serine protease HtrA1 associates with microtubules and inhibits cell migration. Mol Cell Biol. 2009 Aug;29(15):4177-87. doi: 10.1128/MCB.00035-09.
  3. Dewan A, Liu M, Hartman S, Zhang SS, Liu DT, Zhao C, Tam PO, Chan WM, Lam DS, Snyder M, Barnstable C, Pang CP, Hoh J. HTRA1 promoter polymorphism in wetage-related macular degeneration. Science. 2006 Nov 10;314(5801):989-92.
  4. Fukutake T. Cerebral autosomal recessive arteriopathy with subcorticalinfarcts and leukoencephalopathy (CARASIL): from discovery to geneidentification. J Stroke Cerebrovasc Dis. 2011 Mar-Apr;20(2):85-93. doi:10.1016/j.jstrokecerebrovasdis.2010.11.008.
  5. Hara K, Shiga A, Fukutake T, Nozaki H, Miyashita A, Yokoseki A, Kawata H,Koyama A, Arima K, Takahashi T, Ikeda M, Shiota H, Tamura M, Shimoe Y, HirayamaM, Arisato T, Yanagawa S, Tanaka A, Nakano I, Ikeda S, Yoshida Y, Yamamoto T,Ikeuchi T, Kuwano R, Nishizawa M, Tsuji S, Onodera O. Association of HTRA1mutations and familial ischemic cerebral small-vessel disease. N Engl J Med. 2009Apr 23;360(17):1729-39. doi: 10.1056/NEJMoa0801560.
  6. Kanda A, Chen W, Othman M, Branham KE, Brooks M, Khanna R, He S, Lyons R,Abecasis GR, Swaroop A. A variant of mitochondrial protein LOC387715/ARMS2, notHTRA1, is strongly associated with age-related macular degeneration. Proc NatlAcad Sci U S A. 2007 Oct 9;104(41):16227-32.
  7. Shiga A, Nozaki H, Yokoseki A, Nihonmatsu M, Kawata H, Kato T, Koyama A, ArimaK, Ikeda M, Katada S, Toyoshima Y, Takahashi H, Tanaka A, Nakano I, Ikeuchi T,Nishizawa M, Onodera O. Cerebral small-vessel disease protein HTRA1 controls the amount of TGF-β1 via cleavage of proTGF-β1. Hum Mol Genet. 2011 May1;20(9):1800-10. doi: 10.1093/hmg/ddr063.
  8. Tong Y, Liao J, Zhang Y, Zhou J, Zhang H, Mao M. LOC387715/HTRA1 genepolymorphisms and susceptibility to age-related macular degeneration: A HuGEreview and meta-analysis. Mol Vis. 2010 Oct 5;16:1958-81. Review.
  9. Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, Chen H, Zhao Y, PearsonE, Li X, Chien J, Dewan A, Harmon J, Bernstein PS, Shridhar V, Zabriskie NA, Hoh J, Howes K, Zhang K. A variant of the HTRA1 gene increases susceptibility toage-related macular degeneration. Science. 2006 Nov 10;314(5801):992-3.
  10. Yang Z, Tong Z, Chen Y, Zeng J, Lu F, Sun X, Zhao C, Wang K, Davey L, Chen H, London N, Muramatsu D, Salasar F, Carmona R, Kasuga D, Wang X, Bedell M, Dixie M,Zhao P, Yang R, Gibbs D, Liu X, Li Y, Li C, Li Y, Campochiaro B, Constantine R,Zack DJ, Campochiaro P, Fu Y, Li DY, Katsanis N, Zhang K. Genetic and functional dissection of HTRA1 and LOC387715 in age-related macular degeneration. PLoSGenet. 2010 Feb 5;6(2):e1000836. doi: 10.1371/journal.pgen.1000836.
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