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Xu, C. Huntington Disease. Encyclopedia. Available online: https://encyclopedia.pub/entry/4123 (accessed on 28 September 2026).
Xu C. Huntington Disease. Encyclopedia. Available at: https://encyclopedia.pub/entry/4123. Accessed September 28, 2026.
Xu, Camila. "Huntington Disease" Encyclopedia, https://encyclopedia.pub/entry/4123 (accessed September 28, 2026).
Xu, C. (2020, December 23). Huntington Disease. In Encyclopedia. https://encyclopedia.pub/entry/4123
Xu, Camila. "Huntington Disease." Encyclopedia. Web. 23 December, 2020.
Huntington Disease
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/huntington-disease

Huntington disease is a progressive brain disorder that causes uncontrolled movements, emotional problems, and loss of thinking ability (cognition).

genetic conditions

References

  1. Bates GP. History of genetic disease: the molecular genetics of Huntingtondisease - a history. Nat Rev Genet. 2005 Oct;6(10):766-73. doi: 10.1038/nrg1686. Review.
  2. Caron NS, Wright GEB, Hayden MR. Huntington Disease. 1998 Oct 23 [updated 2020Jun 11]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K,Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University ofWashington, Seattle; 1993-2020. Available fromhttp://www.ncbi.nlm.nih.gov/books/NBK1305/
  3. Gonzalez-Alegre P, Afifi AK. Clinical characteristics of childhood-onset(juvenile) Huntington disease: report of 12 patients and review of theliterature. J Child Neurol. 2006 Mar;21(3):223-9.
  4. Imarisio S, Carmichael J, Korolchuk V, Chen CW, Saiki S, Rose C, Krishna G,Davies JE, Ttofi E, Underwood BR, Rubinsztein DC. Huntington's disease: frompathology and genetics to potential therapies. Biochem J. 2008 Jun1;412(2):191-209. doi: 10.1042/BJ20071619. Review.
  5. Jones L, Hughes A. Pathogenic mechanisms in Huntington's disease. Int RevNeurobiol. 2011;98:373-418. doi: 10.1016/B978-0-12-381328-2.00015-8. Review.
  6. Kent A. Huntington's disease. Nurs Stand. 2004 Apr 21-27;18(32):45-51; quiz52-3. Review.
  7. Maiuri T, Mocle AJ, Hung CL, Xia J, van Roon-Mom WM, Truant R. Huntingtin is ascaffolding protein in the ATM oxidative DNA damage response complex. Hum MolGenet. 2017 Jan 15;26(2):395-406. doi: 10.1093/hmg/ddw395.
  8. Sturrock A, Leavitt BR. The clinical and genetic features of Huntingtondisease. J Geriatr Psychiatry Neurol. 2010 Dec;23(4):243-59. doi:10.1177/0891988710383573.
  9. Tost H, Wendt CS, Schmitt A, Heinz A, Braus DF. Huntington's disease:phenomenological diversity of a neuropsychiatric condition that challengestraditional concepts in neurology and psychiatry. Am J Psychiatry. 2004Jan;161(1):28-34.
  10. Walker FO. Huntington's disease. Lancet. 2007 Jan 20;369(9557):218-28. Review.
  11. Young AB. Huntingtin in health and disease. J Clin Invest. 2003Feb;111(3):299-302. Review.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Camila Xu
View Times: 811
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 23 Dec 2020
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