Giant Congenital Melanocytic Nevus

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Xu, C. Giant Congenital Melanocytic Nevus. Encyclopedia. Available online: https://encyclopedia.pub/entry/4001 (accessed on 26 September 2026).

Xu C. Giant Congenital Melanocytic Nevus. Encyclopedia. Available at: https://encyclopedia.pub/entry/4001. Accessed September 26, 2026.

Xu, Camila. "Giant Congenital Melanocytic Nevus" Encyclopedia, https://encyclopedia.pub/entry/4001 (accessed September 26, 2026).

Xu, C. (2020, December 23). Giant Congenital Melanocytic Nevus. In Encyclopedia. https://encyclopedia.pub/entry/4001

Xu, Camila. "Giant Congenital Melanocytic Nevus." Encyclopedia. Web. 23 December, 2020.

Giant Congenital Melanocytic Nevus

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/giant-congenital-melanocytic-nevus

Giant congenital melanocytic nevus is a skin condition characterized by an abnormally dark, noncancerous skin patch (nevus) that is composed of pigment-producing cells called melanocytes. It is present from birth (congenital) or is noticeable soon after birth.

genetic conditions

References

Charbel C, Fontaine RH, Malouf GG, Picard A, Kadlub N, El-Murr N, How-Kit A,Su X, Coulomb-L'Hermine A, Tost J, Mourah S, Aractingi S, Guégan S. NRAS mutationis the sole recurrent somatic mutation in large congenital melanocytic nevi. JInvest Dermatol. 2014 Apr;134(4):1067-1074. doi: 10.1038/jid.2013.429.
Etchevers HC. Hiding in plain sight: molecular genetics applied to giantcongenital melanocytic nevi. J Invest Dermatol. 2014 Apr;134(4):879-882. doi:10.1038/jid.2013.531.
Krengel S, Scope A, Dusza SW, Vonthein R, Marghoob AA. New recommendations forthe categorization of cutaneous features of congenital melanocytic nevi. J AmAcad Dermatol. 2013 Mar;68(3):441-51. doi: 10.1016/j.jaad.2012.05.043.
Rasmussen BS, Henriksen TF, Kølle SF, Schmidt G. Giant congenital melanocytic nevus: report from 30 years of experience in a single department. Ann Plast Surg.2015 Feb;74(2):223-9. doi: 10.1097/SAP.0b013e3182920c3d.
Salgado CM, Basu D, Nikiforova M, Bauer BS, Johnson D, Rundell V, GrunwaldtLJ, Reyes-Múgica M. BRAF mutations are also associated with neurocutaneousmelanocytosis and large/giant congenital melanocytic nevi. Pediatr Dev Pathol.2015 Jan-Feb;18(1):1-9. doi: 10.2350/14-10-1566-OA.1.
Viana AC, Gontijo B, Bittencourt FV. Giant congenital melanocytic nevus. AnBras Dermatol. 2013 Nov-Dec;88(6):863-78. doi: 10.1590/abd1806-4841.20132233.Review. Erratum in: An Bras Dermatol. 2014 Jan-Feb;89(1):190.
Yun SJ, Kwon OS, Han JH, Kweon SS, Lee MW, Lee DY, Kim MB, Kim YC, Yoon TY,Chung KY, Kim IH, Kim KH, Suh KS, Lee SJ, Seo YJ, Kim KH, Park HJ, Roh MR, AhnKJ, Yoon TJ, Kim MH, Li KS, Park JS, Shin BS, Ko JY, Ahn HH, Kim HJ, Park SD,Jang SJ, Won YH. Clinical characteristics and risk of melanoma development fromgiant congenital melanocytic naevi in Korea: a nationwide retrospective study. BrJ Dermatol. 2012 Jan;166(1):115-23. doi: 10.1111/j.1365-2133.2011.10636.x.

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Subjects: Genetics & Heredity

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Entry Collection: MedlinePlus

Update Date: 23 Dec 2020

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