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Lactoferrin (LF) is a protein belonging to the transferrin family, discovered for the first time in cow milk in 1939. It is produced by the epithelial mucosa. It is present in milk and colostrum, but can also be found in tears, saliva, gastric mucosa, the spleen, lymph nodes, skin, and even white blood cells. LF accounts for about 1% of whey proteins. Its concentration is highest in colostrum, but the level is not constant and decreases over the course of lactation, reaching its lowest values in mature milk. lactoferrin is used as an ingredient in food but mainly in pharmaceuticals and cosmetics. In the European Union, bovine lactoferrin has been legally approved for use as a food ingredient since 2012.
Product Type | Product Name | Lactoferrin Content | Use | Web Page Link |
---|---|---|---|---|
Cream | Endvir Simplex (Vitis Pharma) | 6% |
|
http://vitispharma.pl/katalog/produkt/produkty/endvir/endvir-simplex (accessed on 16 May 2022) |
Cream | Acnex (Farmina Ltd.) | No data |
|
https://farmina.pl/product/acnex-krem/ (accessed on 16 May 2022) |
Capsules | Lactoferrin (Pharmabest) | 100 mg/capsule |
|
https://pharmabest.pl/sklep/produkt/laktoferyna-kapsulki/ (accessed on 16 May 2022) |
Capsules | Lactoferrin (Jarrow Formulas) | 250 mg/capsule |
|
https://jarrow.com/products/lactoferrin-250-mg-60-capsules (accessed on 16 May 2022) |
Capsules | IronSorb + Lactoferrin (Jarrow Formulas) | 200 mg/capsule |
|
https://jarrow.com/products/ironsorb-lactoferrin-60-capsules (accessed on 16 May 2022) |
Capsules | Lactoferrin LFS 90% 100 mg (Aliness—MedicaLine) | 100 mg/capsule |
|
https://aliness.pl/pl/p/Lactoferrin-LFS-90-100-mg-x-30-kapsulek/228 (accessed on 16 May 2022) |
Oral drops | Lactoferrin (Pharmabest) | 100 mg/12 drops |
|
https://pharmabest.pl/laktoferyna-krople-doustne/ (accessed on 16 May 2022) |
Sachets | Lactoferrin (Pharmabest) | 100 mg/sachet |
|
https://pharmabest.pl/sklep/produkt/laktoferyna-saszetki/ (accessed on 16 May 2022) |
Sachets | Fibraxine (Alfasigma) | 50 mg/sachet |
|
https://www.alfasigma.com/ (accessed on 16 May 2022) |
Dragées | Fiorda Junior (PhytoPharm) | 6 mg/dragée |
|
http://phytopharm.pl/en/fiorda (accessed on 16 May 2022) |
Toothpaste | Lactoferrin Toothpaste (DENTE91) | No data |
|
https://dente91.com/dente91 (accessed on 16 May 2022) |
Mouthwash | Lactoferrin Mouthwash (DENTE91) |
No data |
|
https://dente91.com/dente-91 (accessed on 16 May 2022) |
Food Category | Maximum Level of bLF |
---|---|
Infant formulae and follow-on formulae within the meaning of Regulation (EU) No 609/2013 (ready to drink) | 100 mg/100 mL |
Dairy-based foods for small children (ready-to-eat) | 200 mg/100 g |
Processed cereal products (solid) | 670 mg/100 g |
Food for special medical purposes within the meaning of Regulation (EU) No 609/2013 | Up to 3 g/day |
Milk-based beverages | 200 mg/100 g |
Powdered milk-based drink mixes (ready-to-drink) | 330 mg/100 g |
Beverages based on fermented milk (including yoghurt drinks) | 50 mg/100 g |
Non-alcoholic drinks | 120 mg/100 g |
Yoghurt-based products | 80 mg/100 g |
Cheese-based products | 2000 mg/100 g |
Ice cream | 130 mg/100 g |
Cakes and pastries | 1000 mg/100 g |
Candies | 750 mg/100 g |
Chewing gum | 3000 mg/100 g |
Product Type | Product Name | Lactoferrin Content | Country of Manufacture | Use | Web Page Link |
---|---|---|---|---|---|
Modified powdered milk (up to 1 year of age) | Morinaga Hagukumi (Morinaga Milk Industry Co., Ltd) |
80 mg/100 g powder |
Tokio, Japan |
|
https://www.morinagamilk.co.jp/english/products/jp/infantformula.php (accessed on 17 May 2022) |
Modified powdered milk (up to 1 year of age) | Enfamil Enspire Infant Formula (Mead Johnson & Company) |
<2% | Chicago, IL, USA |
|
https://www.enfamil.com/products/enfamil-enspire-infant-formula/ (accessed on 17 May 2022) |
Mleko Modified powdered milk (from 12 months to 3 years of age) | Morinaga Chil-mil (Morinaga Milk Industry Co., Ltd) |
55 mg/100 g powder |
Tokio, Japan |
|
https://www.morinagamilk.co.jp/english/products/jp/infantformula.php (accessed on 17 May 2022) |
Yoghurt | Lactoferrin Yogurt (Morinaga Milk Industry Co., Ltd) | 100 mg | Tokio, Japan |
|
https://www.morinagamilk.co.jp/english/products/jp/yogurt.php (accessed on 17 May 2022) |
Chewing gum with lactoferrin and manuka honey | Blue®m dental chewing gum (Blue®m) | No data | VH Wijhe, Netherlands |
|
https://bluemcare.com/product/dental-chewing-gum/ (accessed on 17 May 2022) |
Carbonated drink with lactoferrin | Immune + (Beston Global Foods) |
No data | Adelaide, SA, Australia |
|
https://immuneplus.com.au/ (accessed on 17 May 2022) |
Fruit gums for children | C + Zinc Jelly (NANA and TAKA) |
No data | Taiwan |
|
https://www.hktvmall.com/hktv/en/main/Hong-Kong-Chien-Cao-Tong-Medical-Limited/s/H6449002/Personal-Care-%26-Health/Personal-Care-%26-Health/Health/Immunity/CZinc-Jelly/p/H6449002_S_CCT10867?scrollTo=recommendationTab (accessed on 17 May 2022) |