HFE Gene

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1		Dean Liu	+ 773 word(s)	773	2020-12-15 07:56:12

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Liu, D. HFE Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/3861 (accessed on 29 September 2026).

Liu D. HFE Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/3861. Accessed September 29, 2026.

Liu, Dean. "HFE Gene" Encyclopedia, https://encyclopedia.pub/entry/3861 (accessed September 29, 2026).

Liu, D. (2020, December 22). HFE Gene. In Encyclopedia. https://encyclopedia.pub/entry/3861

Liu, Dean. "HFE Gene." Encyclopedia. Web. 22 December, 2020.

HFE Gene

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/hfe

Homeostatic iron regulator

genes

References

Andrews NC. Molecular control of iron metabolism. Best Pract Res ClinHaematol. 2005 Jun;18(2):159-69. Review.
Barton JC, Edwards CQ, Acton RT. HFE gene: Structure, function, mutations, andassociated iron abnormalities. Gene. 2015 Dec 15;574(2):179-92. doi:10.1016/j.gene.2015.10.009.
Egger NG, Goeger DE, Payne DA, Miskovsky EP, Weinman SA, Anderson KE.Porphyria cutanea tarda: multiplicity of risk factors including HFE mutations,hepatitis C, and inherited uroporphyrinogen decarboxylase deficiency. Dig DisSci. 2002 Feb;47(2):419-26.
Fleming RE, Britton RS. Iron Imports. VI. HFE and regulation of intestinaliron absorption. Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G590-4.Review.
Fleming RE. Iron sensing as a partnership: HFE and transferrin receptor 2.Cell Metab. 2009 Mar;9(3):211-2. doi: 10.1016/j.cmet.2009.02.004.
Ganz T. Iron homeostasis: fitting the puzzle pieces together. Cell Metab. 2008Apr;7(4):288-90. doi: 10.1016/j.cmet.2008.03.008. Review.
Kaczorowska-Hac B, Luszczyk M, Antosiewicz J, Ziolkowski W,Adamkiewicz-Drozynska E, Mysliwiec M, Milosz E, Kaczor JJ. HFE Gene Mutations andIron Status in 100 Healthy Polish Children. J Pediatr Hematol Oncol. 2017Jul;39(5):e240-e243. doi: 10.1097/MPH.0000000000000826.
Nemeth E, Ganz T. Regulation of iron metabolism by hepcidin. Annu Rev Nutr.2006;26:323-42. Review.
Pantopoulos K. Inherited Disorders of Iron Overload. Front Nutr. 2018 Oct29;5:103. doi: 10.3389/fnut.2018.00103.
Phillips JD, Bergonia HA, Reilly CA, Franklin MR, Kushner JP. A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5079-84.
Sebastiani G, Walker AP. HFE gene in primary and secondary hepatic ironoverload. World J Gastroenterol. 2007 Sep 21;13(35):4673-89. Review.
Vujić M. Molecular basis of HFE-hemochromatosis. Front Pharmacol. 2014 Mar11;5:42. doi: 10.3389/fphar.2014.00042.
Zaahl MG, Merryweather-Clarke AT, Kotze MJ, van der Merwe S, Warnich L, RobsonKJ. Analysis of genes implicated in iron regulation in individuals presentingwith primary iron overload. Hum Genet. 2004 Oct;115(5):409-17.

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Subjects: Genetics & Heredity

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Entry Collection: MedlinePlus

Update Date: 22 Dec 2020

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