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Liu, D. HADHA Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/3835 (accessed on 28 September 2026).
Liu D. HADHA Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/3835. Accessed September 28, 2026.
Liu, Dean. "HADHA Gene" Encyclopedia, https://encyclopedia.pub/entry/3835 (accessed September 28, 2026).
Liu, D. (2020, December 22). HADHA Gene. In Encyclopedia. https://encyclopedia.pub/entry/3835
Liu, Dean. "HADHA Gene." Encyclopedia. Web. 22 December, 2020.
HADHA Gene
Edit

Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

genes

References

  1. Angdisen J, Moore VD, Cline JM, Payne RM, Ibdah JA. Mitochondrialtrifunctional protein defects: molecular basis and novel therapeutic approaches. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Mar;5(1):27-40. Review.
  2. Blish KR, Ibdah JA. Maternal heterozygosity for a mitochondrial trifunctional protein mutation as a cause for liver disease in pregnancy. Med Hypotheses.2005;64(1):96-100.
  3. Choi JH, Yoon HR, Kim GH, Park SJ, Shin YL, Yoo HW. Identification of novelmutations of the HADHA and HADHB genes in patients with mitochondrialtrifunctional protein deficiency. Int J Mol Med. 2007 Jan;19(1):81-7.
  4. den Boer ME, Wanders RJ, Morris AA, IJlst L, Heymans HS, Wijburg FA.Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency: clinical presentation and follow-up of 50 patients. Pediatrics. 2002 Jan;109(1):99-104.
  5. Gutiérrez Junquera C, Balmaseda E, Gil E, Martínez A, Sorli M, Cuartero I,Merinero B, Ugarte M. Acute fatty liver of pregnancy and neonatal long-chain3-hydroxyacyl-coenzyme A dehydrogenase (LCHAD) deficiency. Eur J Pediatr. 2009Jan;168(1):103-6. doi: 10.1007/s00431-008-0696-z.
  6. Ibdah JA, Bennett MJ, Rinaldo P, Zhao Y, Gibson B, Sims HF, Strauss AW. Afetal fatty-acid oxidation disorder as a cause of liver disease in pregnantwomen. N Engl J Med. 1999 Jun 3;340(22):1723-31.
  7. Ibdah JA, Yang Z, Bennett MJ. Liver disease in pregnancy and fetal fatty acid oxidation defects. Mol Genet Metab. 2000 Sep-Oct;71(1-2):182-9. Review.
  8. Oey NA, den Boer ME, Wijburg FA, Vekemans M, Augé J, Steiner C, Wanders RJ,Waterham HR, Ruiter JP, Attié-Bitach T. Long-chain fatty acid oxidation duringearly human development. Pediatr Res. 2005 Jun;57(6):755-9.
  9. Shekhawat PS, Matern D, Strauss AW. Fetal fatty acid oxidation disorders,their effect on maternal health and neonatal outcome: impact of expanded newborn screening on their diagnosis and management. Pediatr Res. 2005 May;57(5 Pt2):78R-86R.
  10. Sims HF, Brackett JC, Powell CK, Treem WR, Hale DE, Bennett MJ, Gibson B,Shapiro S, Strauss AW. The molecular basis of pediatric long chain3-hydroxyacyl-CoA dehydrogenase deficiency associated with maternal acute fattyliver of pregnancy. Proc Natl Acad Sci U S A. 1995 Jan 31;92(3):841-5.
  11. Spiekerkoetter U, Khuchua Z, Yue Z, Bennett MJ, Strauss AW. Generalmitochondrial trifunctional protein (TFP) deficiency as a result of either alpha-or beta-subunit mutations exhibits similar phenotypes because mutations in eithersubunit alter TFP complex expression and subunit turnover. Pediatr Res. 2004Feb;55(2):190-6.
  12. Spiekerkoetter U, Mueller M, Cloppenburg E, Motz R, Mayatepek E, Bueltmann B, Korenke C. Intrauterine cardiomyopathy and cardiac mitochondrial proliferation inmitochondrial trifunctional protein (TFP) deficiency. Mol Genet Metab. 2008Aug;94(4):428-30. doi: 10.1016/j.ymgme.2008.04.002.
  13. Tyni T, Pihko H. Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. ActaPaediatr. 1999 Mar;88(3):237-45. Review.
  14. Yang Z, Yamada J, Zhao Y, Strauss AW, Ibdah JA. Prospective screening forpediatric mitochondrial trifunctional protein defects in pregnancies complicated by liver disease. JAMA. 2002 Nov 6;288(17):2163-6.
  15. Yang Z, Zhao Y, Bennett MJ, Strauss AW, Ibdah JA. Fetal genotypes andpregnancy outcomes in 35 families with mitochondrial trifunctional proteinmutations. Am J Obstet Gynecol. 2002 Sep;187(3):715-20.
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