GRN Gene

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1		Dean Liu	+ 694 word(s)	694	2020-12-15 07:55:32

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Liu, D. GRN Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/3823 (accessed on 28 September 2026).

Liu D. GRN Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/3823. Accessed September 28, 2026.

Liu, Dean. "GRN Gene" Encyclopedia, https://encyclopedia.pub/entry/3823 (accessed September 28, 2026).

Liu, D. (2020, December 22). GRN Gene. In Encyclopedia. https://encyclopedia.pub/entry/3823

Liu, Dean. "GRN Gene." Encyclopedia. Web. 22 December, 2020.

GRN Gene

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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/grn

Granulin precursor

genes

References

Cruts M, Van Broeckhoven C. Loss of progranulin function in frontotemporallobar degeneration. Trends Genet. 2008 Apr;24(4):186-94. doi:10.1016/j.tig.2008.01.004.
Eriksen JL, Mackenzie IR. Progranulin: normal function and role inneurodegeneration. J Neurochem. 2008 Jan;104(2):287-97.
Huin V, Barbier M, Bottani A, Lobrinus JA, Clot F, Lamari F, Chat L, Rucheton B, Fluchère F, Auvin S, Myers P, Gelot A, Camuzat A, Caillaud C, Jornéa L,Forlani S, Saracino D, Duyckaerts C, Brice A, Durr A, Le Ber I. Homozygous GRNmutations: new phenotypes and new insights into pathological and molecularmechanisms. Brain. 2020 Jan 1;143(1):303-319. doi: 10.1093/brain/awz377. Erratum in: Brain. 2020 Mar 1;143(3):e24.
Le Ber I, van der Zee J, Hannequin D, Gijselinck I, Campion D, Puel M,Laquerrière A, De Pooter T, Camuzat A, Van den Broeck M, Dubois B, Sellal F,Lacomblez L, Vercelletto M, Thomas-Antérion C, Michel BF, Golfier V, Didic M,Salachas F, Duyckaerts C, Cruts M, Verpillat P, Van Broeckhoven C, Brice A;French Research Network on FTD/FTD-MND. Progranulin null mutations in bothsporadic and familial frontotemporal dementia. Hum Mutat. 2007 Sep;28(9):846-55.
Paushter DH, Du H, Feng T, Hu F. The lysosomal function of progranulin, aguardian against neurodegeneration. Acta Neuropathol. 2018 Jul;136(1):1-17. doi: 10.1007/s00401-018-1861-8.
Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E,Wood EM, Yu CE, Josephs K, Sorenson E, Womack KB, Weintraub S, Pickering-BrownSM, Schofield PR, Brooks WS, Van Deerlin VM, Snowden J, Clark CM, Kertesz A,Boylan K, Ghetti B, Neary D, Schellenberg GD, Beach TG, Mesulam M, Mann D,Grafman J, Mackenzie IR, Feldman H, Bird T, Petersen R, Knopman D, Boeve B,Geschwind DH, Miller B, Wszolek Z, Lippa C, Bigio EH, Dickson D, Graff-Radford N,Hutton M. Phenotypic variability associated with progranulin haploinsufficiencyin patients with the common 1477C-->T (Arg493X) mutation: an internationalinitiative. Lancet Neurol. 2007 Oct;6(10):857-68. Erratum in: Lancet Neurol. 2007Dec;6(12):1037.
Yu CE, Bird TD, Bekris LM, Montine TJ, Leverenz JB, Steinbart E, Galloway NM, Feldman H, Woltjer R, Miller CA, Wood EM, Grossman M, McCluskey L, Clark CM,Neumann M, Danek A, Galasko DR, Arnold SE, Chen-Plotkin A, Karydas A, Miller BL, Trojanowski JQ, Lee VM, Schellenberg GD, Van Deerlin VM. The spectrum ofmutations in progranulin: a collaborative study screening 545 cases ofneurodegeneration. Arch Neurol. 2010 Feb;67(2):161-70. doi:10.1001/archneurol.2009.328.

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