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HandWiki. Wrinkle. Encyclopedia. Available online: https://encyclopedia.pub/entry/37567 (accessed on 17 September 2026).
HandWiki. Wrinkle. Encyclopedia. Available at: https://encyclopedia.pub/entry/37567. Accessed September 17, 2026.
HandWiki. "Wrinkle" Encyclopedia, https://encyclopedia.pub/entry/37567 (accessed September 17, 2026).
HandWiki. (2022, December 01). Wrinkle. In Encyclopedia. https://encyclopedia.pub/entry/37567
HandWiki. "Wrinkle." Encyclopedia. Web. 01 December, 2022.
Wrinkle
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The content is sourced from: https://handwiki.org/wiki/Medicine:Wrinkle

A wrinkle, also known as a rhytide, is a fold, ridge or crease in the skin or on fabric. Skin wrinkles typically appear as a result of aging processes such as glycation, habitual sleeping positions, loss of body mass, or temporarily, as the result of prolonged immersion in water. Age wrinkling in the skin is promoted by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors.

glycation wrinkle wrinkling

References

  1. Wang, Jicun; Michelitsch, Thomas; Wunderlin, Arne; Mahadeva, Ravi (2009). "Aging as a consequence of Misrepair –a novel theory of aging". arXiv:0904.0575. //arxiv.org/abs/0904.0575
  2. Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Aging as a process of accumulation of Misrepairs". arXiv:1503.07163. Cite has empty unknown parameter: |1= (help) //arxiv.org/abs/1503.07163
  3. Wang-Michelitsch, Jicun; Michelitsch, Thomas (2015). "Tissue fibrosis: a principal evidence for the central role of Misrepairs in aging". arXiv:1505.01376. //arxiv.org/abs/1505.01376
  4. Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg 38 (4): 244–247. doi:10.1080/02844310410027257.  https://dx.doi.org/10.1080%2F02844310410027257
  5. Fulton, James E.; Gaminchi, F. (1999). "Sleep Lines". Dermatol Surg 25 (1): 59–62. doi:10.1046/j.1524-4725.1999.08073.x. PMID 9935097.  https://dx.doi.org/10.1046%2Fj.1524-4725.1999.08073.x
  6. Sarifakioglu, Nedim; Terzioglu, A.; Ates, L.; Aslan, G. (2004). "A New Phenomenon: 'Sleep Lines' on the Face". Scan J Plast Reconstr Surg Hand Surg 38 (4): 244–247 [246]. doi:10.1080/02844310410027257.  https://dx.doi.org/10.1080%2F02844310410027257
  7. Mark Changizi; Romann Weber; Ritesh Kotecha; Joseph Palazzo (2011). "Are Wet-Induced Wrinkled Fingers Primate Rain Treads?". Brain, Behavior and Evolution 77 (4): 286–90. doi:10.1159/000328223. PMID 21701145.  https://dx.doi.org/10.1159%2F000328223
  8. Kareklas, Kyriacos; Nettle, Daniel; Smulders, Tom V (January 9, 2013). "Water-induced finger wrinkles improve handling of wet objects". Biol. Lett. 9 (2): 20120999. doi:10.1098/rsbl.2012.0999. PMID 23302867. PMC 3639753. http://rsbl.royalsocietypublishing.org/content/9/2/20120999. Retrieved 28 January 2013. 
  9. Haseleu, Julia; Omerbašić, Damir; Frenzel, Henning; Gross, Manfred; Lewin, Gary R. (2014). Goldreich, Daniel. ed. "Water-Induced Finger Wrinkles Do Not Affect Touch Acuity or Dexterity in Handling Wet Objects". PLoS ONE 9: e84949. doi:10.1371/journal.pone.0084949. PMID 24416318. Bibcode: 2014PLoSO...984949H.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3885627
  10. Dr Karl's Homework - Skin Wrinkles in Water (26/1/2000) http://www.abc.net.au/science/k2/homework/s95618.htm
  11. Einar P.V. Wilder-Smith; Adeline Chow (2003). "Water-immersion wrinkeling is due to vasoconstriction". Muscle & Nerve 27 (3): 307–311. doi:10.1002/mus.10323. PMID 12635117.  https://dx.doi.org/10.1002%2Fmus.10323
  12. Einar P. V. Wilder-Smith (2004). "Water immersion wrinkling". Clinical Autonomic Research 14 (2): 125–131. doi:10.1007/s10286-004-0172-4. PMID 15095056.  https://dx.doi.org/10.1007%2Fs10286-004-0172-4
  13. H. Zhai, K.P. Whilem H. L. Maibach (2007). Dermatotoxicology. pp. 280–281. 
  14. G Alvarez, J Eurolo; P Canales; (1980). "Finger wrinkling after immersion in water". British Medical Journal 281 (6240): 586–587. doi:10.1136/bmj.281.6240.586-a. PMID 7427379.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1713922
  15. "Topical retinoids in the treatment of photoaging". J Cosmet Dermatol 4 (2): 130–4. June 2005. doi:10.1111/j.1473-2165.2005.40215.x. PMID 17166212.  https://dx.doi.org/10.1111%2Fj.1473-2165.2005.40215.x
  16. "Safety and efficacy of NeuroBloc (botulinum toxin type B) in type A-resistant cervical dystonia". Neurology 53 (7): 1431–8. 1999. doi:10.1212/WNL.53.7.1431. PMID 10534247.  https://dx.doi.org/10.1212%2FWNL.53.7.1431
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