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HandWiki. Β-lactam Antibiotic. Encyclopedia. Available online: https://encyclopedia.pub/entry/36195 (accessed on 05 November 2026).
HandWiki. Β-lactam Antibiotic. Encyclopedia. Available at: https://encyclopedia.pub/entry/36195. Accessed November 05, 2026.
HandWiki. "Β-lactam Antibiotic" Encyclopedia, https://encyclopedia.pub/entry/36195 (accessed November 05, 2026).
HandWiki. (2022, November 24). Β-lactam Antibiotic. In Encyclopedia. https://encyclopedia.pub/entry/36195
HandWiki. "Β-lactam Antibiotic." Encyclopedia. Web. 24 November, 2022.

Β-lactam Antibiotic

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The content is sourced from: https://handwiki.org/wiki/Chemistry:%CE%92-lactam_antibiotic

β-lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a beta-lactam ring in their molecular structure. This includes penicillin derivatives (penams), cephalosporins and cephamycins (cephems), monobactams, carbapenems and carbacephems. Most β-lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organism and are the most widely used group of antibiotics. Until 2003, when measured by sales, more than half of all commercially available antibiotics in use were β-lactam compounds. The first β-lactam antibiotic discovered, penicillin, was isolated from a rare variant of Penicillium notatum (since renamed Penicillium chrysogenum). Bacteria often develop resistance to β-lactam antibiotics by synthesizing a β-lactamase, an enzyme that attacks the β-lactam ring. To overcome this resistance, β-lactam antibiotics can be given with β-lactamase inhibitors such as clavulanic acid.

β-lactam antibiotics penicillium cephalosporins

References

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