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HandWiki. Sarah Teichmann. Encyclopedia. Available online: https://encyclopedia.pub/entry/36162 (accessed on 21 May 2024).
HandWiki. Sarah Teichmann. Encyclopedia. Available at: https://encyclopedia.pub/entry/36162. Accessed May 21, 2024.
HandWiki. "Sarah Teichmann" Encyclopedia, https://encyclopedia.pub/entry/36162 (accessed May 21, 2024).
HandWiki. (2022, November 24). Sarah Teichmann. In Encyclopedia. https://encyclopedia.pub/entry/36162
HandWiki. "Sarah Teichmann." Encyclopedia. Web. 24 November, 2022.
Sarah Teichmann
Edit
embl-ebi bioinformatics fmedsci

1. Introduction

Sarah Amalia Teichmann (born 1975)[1] FMedSci[2] is Head of Cellular Genetics at the Wellcome Sanger Institute[3] and a visiting research group leader at the European Bioinformatics Institute (EMBL-EBI).[4][5] She is also a Director of Research (equivalent to Professor)[6] in the Cavendish Laboratory,[7] at the University of Cambridge and a Senior Research Fellow at Churchill College, Cambridge.

2. Education

Teichmann was educated at the European School, Karlsruhe in Germany from 1981 to 1993 where she completed the European Baccalaureate in 1993.[8]

In 2013 Teichmann was appointed a joint position at the Wellcome Trust Sanger Institute and the European Bioinformatics Institute (EMBL-EBI). From 2005 to 2015 she was a teaching fellow and Director of Studies at Trinity College, Cambridge. Since 2016 Teichmann has served as the head of Cellular Genetics at the Wellcome Trust Sanger Institute[3] and a visiting research group leader at the EBI.[5]

Teichmann's research[9][10][11][12] investigates gene expression[13][14][15] and protein complex assembly[16] using both wet laboratory and computational biology techniques.[17] In particular her research group:

"...seeks to elucidate the principles of protein structure evolution, higher order protein structure and protein folding, and the principles underlying protein complex formation and organization. We have a longstanding interest in understanding gene expression regulation, and in our wetlab at the Sanger Institute use mouse T helper cells as a model of cell differentiation.[18] "

Teichmann's research has been funded by the European Research Council (ERC), the Medical Research Council (MRC), the Biotechnology and Biological Sciences Research Council (BBSRC),[19] the Wellcome Trust, the European Molecular Biology Organization (EMBO), the Framework Programmes for Research and Technological Development and the European Cooperation in Science and Technology (COST).[20]

(As of 2015) Teichmann has supervised several PhD students to completion[20][21][22][23][24][25][26][27][28][29] and several postdoctoral researchers who have gone on to become Principal investigators (PIs).[20][30][31][32]

Awards and honours

Teichmann has won a number of awards. In 2010, she was awarded Colworth Medal from the Biochemical Society.[33][34] In 2012, Teichman was awarded the Francis Crick Medal and Lecture, membership of the European Molecular Biology Organization (EMBO)[35] and the Lister Prize from the Lister Institute of Preventive Medicine.[36] In 2015 she was awarded the Michael and Kate Bárány Award for young investigators by the Biophysical Society[37] and the EMBO Gold Medal. Teichmann was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2015. Her citation on election reads:

" Sarah Teichmann is Research Group Leader at EMBL-European Bioinformatics Institute and has made major contributions to biology over the past 15 years. A fundamental discovery was her work to define key biophysical mechanisms in protein complex assembly, showing that protein complexes assemble via distinct, ordered pathways. She showed that these assembly pathways are conserved in evolution and how they may be predicted from 3D structure. Her databases and computational analysis methods have had a broad and deep impact on the community. She represents a new breed of scientists at the interface between computational and experimental molecular biology.[2] "

Teichmann has also been an activist for women's careers in science through enabling scientists in families to advance their careers while working part-time.[38] She chaired a Sex in Science debate at the Wellcome Trust on balancing family life with working in research. Teichmann was elected an ISCB Fellow in 2016 by the International Society for Computational Biology.[39]

3. Personal Life

Teichmann has two daughters.[40][41] Teichmann is the co-author of the children's language education novel Teenage Detectives,[42] which she wrote as a teenager together with her mother Dr. Virginia Teichmann, an English-language university lecturer in Karlsruhe.[43]

Further Reading
In this part, we encourage you to list the link of papers wrote by the character, or published reviews/articles about his/her academic contributions. Edit

References

  1. Teichmann, Sarah (2007). "Sarah Amalia Teichmann PhD MA BA (Hons cantab) CV". Laboratory of Molecular Biology. Archived from the original on 2013-02-26. https://web.archive.org/web/20130226050525/http://www.mrc-lmb.cam.ac.uk/genomes/Sarah/bio_teich07.pdf. 
  2. Anon (2015). "Dr Sarah Teichmann FMedSci". London: Academy of Medical Sciences. Archived from the original on 2015-07-06. https://web.archive.org/web/20150706123113/http://www.acmedsci.ac.uk/fellows/fellows-directory/ordinary-fellows/dr-sarah-teichmann/. 
  3. "Dr Sarah Teichmann, FMedSci, Head of Cellular Genetics". Cambridge: sanger.ac.uk. Archived from the original on 2016-04-15. https://web.archive.org/web/20160415075045/http://www.sanger.ac.uk/people/directory/teichmann-sarah. 
  4. Marx, Vivien (2016). "The Author File: Sarah Teichmann". Nature Methods 13 (4): 279. doi:10.1038/nmeth.3808. ISSN 1548-7091. PMID 27203785.  https://dx.doi.org/10.1038%2Fnmeth.3808
  5. "People & Groups: Sarah Teichmann, Group Leader - Teichmann research group". EMBL-EBI. 2013. Archived from the original on 2013-04-03. https://web.archive.org/web/20130403001859/http://www.ebi.ac.uk/about/people/sarah-teichmann. 
  6. Anon (2013). "Job titles and duties at the University of Cambridge". University of Cambridge. Archived from the original on 2013-07-03. https://web.archive.org/web/20130703200917/http://www.cam.ac.uk/research-staff/employment-and-career-management/employment-and-career-management-scheme/researchers-employment-policies-and-protocols/job-titles-and-duties. 
  7. Anon (2015). "Dr Sarah Teichmann FMedSci". Cambridge. Archived from the original on 2015-09-12. https://web.archive.org/web/20150912194932/http://www.tcm.phy.cam.ac.uk/profiles/sat1003/. 
  8. Luscombe, N. M.; Babu, M. M.; Yu, H; Snyder, M; Teichmann, S. A.; Gerstein, M (2004). "Genomic analysis of regulatory network dynamics reveals large topological changes". Nature 431 (7006): 308–12. doi:10.1038/nature02782. PMID 15372033.  https://dx.doi.org/10.1038%2Fnature02782
  9. {{ACM Portal}} template missing ID and not present in Wikidata.
  10. {{DBLP}} template missing ID and not present in Wikidata.
  11. Sarah Teichmann publications indexed by the Scopus bibliographic database. (Subscription content?) https://www.scopus.com/authid/detail.url?authorId=
  12. Sarah Teichmann publications from Europe PubMed Central https://europepmc.org/authors/
  13. Carninci, P; Kasukawa, T; Katayama, S; Gough, J; Frith, M. C.; Maeda, N; Oyama, R; Ravasi, T et al. (2005). "The transcriptional landscape of the mammalian genome". Science 309 (5740): 1559–63. doi:10.1126/science.1112014. PMID 16141072. https://semanticscholar.org/paper/2677c8aa5ebe0647f1fd7245878e83ca8dab52f5. 
  14. Drosophila 12 Genomes, Consortium; Clark, A. G.; Eisen, M. B.; Smith, D. R.; Bergman, C. M.; Oliver, B; Markow, T. A.; Kaufman, T. C. et al. (2007). "Evolution of genes and genomes on the Drosophila phylogeny". Nature 450 (7167): 203–18. doi:10.1038/nature06341. PMID 17994087.  https://dx.doi.org/10.1038%2Fnature06341
  15. Wilson, D; Charoensawan, V; Kummerfeld, S. K.; Teichmann, S. A. (2008). "DBD--taxonomically broad transcription factor predictions: New content and functionality". Nucleic Acids Research 36 (Database issue): D88–92. doi:10.1093/nar/gkm964. PMID 18073188.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2238844
  16. Levy, E. D.; Teichmann, S (2013). "Structural, Evolutionary, and Assembly Principles of Protein Oligomerization". Oligomerization in Health and Disease. Progress in Molecular Biology and Translational Science. 117. pp. 25–51. doi:10.1016/B978-0-12-386931-9.00002-7. ISBN 9780123869319.  https://dx.doi.org/10.1016%2FB978-0-12-386931-9.00002-7
  17. Perica, T; Kondo, Y; Tiwari, S. P.; McLaughlin, S. H.; Kemplen, K. R.; Zhang, X; Steward, A; Reuter, N et al. (2014). "Evolution of oligomeric state through allosteric pathways that mimic ligand binding". Science 346 (6216): 1254346. doi:10.1126/science.1254346. PMID 25525255.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=4337988
  18. "Teichmann group Research EMBL-EBI". European Bioinformatics Institute. 2013. Archived from the original on 2013-04-02. https://web.archive.org/web/20130402163004/http://www.ebi.ac.uk/research/teichmann. 
  19. Anon (2015). "UK Government research grants awarded to Sarah Teichmann". Research Councils UK. Archived from the original on 2015-03-03. https://web.archive.org/web/20150303105747/http://gtr.rcuk.ac.uk/person/E7D7D43E-7A50-4275-A7D7-CBCA7E9D5E16. 
  20. error
  21. Teichmann, Sarah (2015). "Alumni from Sarah Teichmann's Group". European Bioinformatics Institute. Archived from the original on 2015-02-20. https://www.webcitation.org/6WUCOq6D4?url=https://www.ebi.ac.uk/~saraht/people.html. 
  22. Mohan, Madan Babu (2004). Evolution of transcriptional regulatory networks. jisc.ac.uk (PhD thesis). University of Cambridge. OCLC 890159758. EThOS uk.bl.ethos.616113. https://copac.jisc.ac.uk/id/35564990?style=html
  23. Charoensawan, Varodom (2011). Evolution and dynamics of transcription factors and gene expression patterns. ethos.bl.uk (PhD thesis). University of Cambridge. OCLC 890150091. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609169
  24. De, Subhajyoti (2008). Human genome evolution : investigating protein divergence, polymorphisms and genomic neighbourhood. ethos.bl.uk (PhD thesis). University of Cambridge. OCLC 890154864. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612500
  25. Han, Jay (2007). Structure, function and evolution of protein-protein interactions (PhD thesis). University of Cambridge. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603640
  26. Kummerfeld, Sarah Kay (2006). Towards understanding the protein universe : genome-scale studies of evolution and gene regulation. ethos.bl.uk (PhD thesis). University of Cambridge. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.613658
  27. Levy, Emmanuel Doram (2008). Classification, evolution, and assembly of protein complexes. ethos.bl.uk (PhD thesis). University of Cambridge. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611940
  28. Perica, Tina (2013). Evolutionary and structural dynamics of protein complexes (PhD thesis). University of Cambridge. OCLC 890148231. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607933
  29. Su, Jing (2012). Computational prediction of regulatory elements (PhD thesis). University of Cambridge. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610362
  30. Adryan, B; Teichmann, S. A. (2010). "The developmental expression dynamics of Drosophila melanogaster transcription factors". Genome Biology 11 (4): R40. doi:10.1186/gb-2010-11-4-r40. PMID 20384991.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2884543
  31. Gsponer, J; Futschik, M. E.; Teichmann, S. A.; Babu, M. M. (2008). "Tight regulation of unstructured proteins: From transcript synthesis to protein degradation". Science 322 (5906): 1365–8. doi:10.1126/science.1163581. PMID 19039133.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2803065
  32. Hebenstreit, D; Gu, M; Haider, S; Turner, D. J.; Liò, P; Teichmann, S. A. (2011). "EpiChIP: Gene-by-gene quantification of epigenetic modification levels". Nucleic Acids Research 39 (5): e27. doi:10.1093/nar/gkq1226. PMID 21131282.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3061070
  33. error
  34. Anon (2015). "Women at Cambridge: Sarah Amalia Teichmann". University of Cambridge. Archived from the original on 2015-02-20. https://web.archive.org/web/20150220162433/http://www.cam.ac.uk/women-at-cambridge/profiles/sarah-a-teichmann. 
  35. error
  36. error
  37. "Biophysical Society Names 2015 Award Recipients". Biophysical Society. http://www.biophysics.org/Portals/1/PDFs/Press%20Room/2014/2015%20Award%20Recipients%20press%20release.pdf. 
  38. Gaskell & Kostic (2015). "The Unstoppable Sarah Teichmann on Programing, Motherhood, and Protein Complex Assembly:The Female Scientist". Archived from the original on 2016-04-15. https://www.webcitation.org/6gmZnotu3?url=http://crosstalk.cell.com/blog/sarah-teichmann-on-programming-motherhood-and-complex-assembly. Retrieved 2015-11-25. 
  39. Anon (2017). "ISCB Fellows". International Society for Computational Biology. Archived from the original on 2017-03-20. https://web.archive.org/web/20170320114530/https://www.iscb.org/iscb-fellows. 
  40. Greenstreet, Rosanna (2018). "Sarah Teichmann: 'I wake as early as 4am and think about work'". London: The Guardian. https://www.theguardian.com/money/2018/mar/03/sarah-teichmann-wake-4am-think-about-work. 
  41. Pain, Elisabeth (2015). "Harnessing computer power to understand biology". Science. doi:10.1126/science.caredit.a1500172.  https://dx.doi.org/10.1126%2Fscience.caredit.a1500172
  42. Teichmann, Sarah; Teichmann, Virginia (1991). Cornelsen English Library - Fiction: 8. Schuljahr, Stufe 1 - Teenage Detectives: Textheft. Mit Aufgaben und Activities. Germany: Cornelsen Verlag. ISBN 978-3464053362. 
  43. "The Honeycomb: Dr. Virginia Teichmann: Word Lover". http://www.expat-karlsruhe.com/uploads/media/Honeycomb-Issue1.pdf. Retrieved 2015-12-07. 
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Name: Sarah Teichmann
Born: Apr 1975
Birth
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Title: Research Fellow
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